| A novel myosin-like protein (myocilin) expressed in the connecting cilium of the photoreceptor: molecular cloning, tissue expression, and chromosomal mapping R Kubota, S Noda, Y Wang, S Minoshima, S Asakawa, J Kudoh, ... Genomics 41 (3), 360-369, 1997 | 381 | 1997 |
| Human BAC library: construction and rapid screening S Asakawa, I Abe, Y Kudoh, N Kishi, Y Wang, R Kubota, J Kudoh, ... Gene 191 (1), 69-79, 1997 | 230 | 1997 |
| A comparative study of neurogenesis in the retinal ciliary marginal zone of homeothermic vertebrates R Kubota, JN Hokoc, A Moshiri, C McGuire, TA Reh Developmental brain research 134 (1-2), 31-41, 2002 | 174 | 2002 |
| Emixustat hydrochloride for geographic atrophy secondary to age-related macular degeneration: a randomized clinical trial PJ Rosenfeld, PU Dugel, FG Holz, JS Heier, JA Pearlman, RL Novack, ... Ophthalmology 125 (10), 1556-1567, 2018 | 122 | 2018 |
| Safety and effect on rod function of ACU-4429, a novel small-molecule visual cycle modulator R Kubota, NL Boman, R David, S Mallikaarjun, S Patil, D Birch Retina 32 (1), 183-188, 2012 | 116 | 2012 |
| Effects of potent inhibitors of the retinoid cycle on visual function and photoreceptor protection from light damage in mice A Maeda, T Maeda, M Golczak, Y Imanishi, P Leahy, R Kubota, ... Molecular pharmacology 70 (4), 1220-1229, 2006 | 106 | 2006 |
| Extracellular myocilin affects activity of human trabecular meshwork cells K Wentz‐Hunter, R Kubota, X Shen, BYJT Yue Journal of cellular physiology 200 (1), 45-52, 2004 | 85 | 2004 |
| Genomic organization of the human myocilin gene (MYOC) responsible for primary open angle glaucoma (GLC1A) R Kubota, J Kudoh, Y Mashima, S Asakawa, S Minoshima, JF Hejtmancik, ... Biochemical and biophysical research communications 242 (2), 396-400, 1998 | 84 | 1998 |
| Visual cycle modulation as an approach toward preservation of retinal integrity C Bavik, SH Henry, Y Zhang, K Mitts, T McGinn, E Budzynski, A Pashko, ... PLoS One 10 (5), e0124940, 2015 | 83 | 2015 |
| Phase 1, dose-ranging study of emixustat hydrochloride (ACU-4429), a novel visual cycle modulator, in healthy volunteers RYO Kubota, S Al-Fayoumi, S Mallikaarjun, S Patil, C Bavik, JW Chandler Retina 34 (3), 603-609, 2014 | 82 | 2014 |
| Human retina-specific amine oxidase (RAO): cDNA cloning, tissue expression, and chromosomal mapping Y Imamura, R Kubota, Y Wang, S Asakawa, J Kudoh, Y Mashima, ... Genomics 40 (2), 277-283, 1997 | 82 | 1997 |
| Protective effect of crocin against blue light–and white light–mediated photoreceptor cell death in bovine and primate retinal primary cell culture A Laabich, GP Vissvesvaran, KL Lieu, K Murata, TE McGinn, ... Investigative ophthalmology & visual science 47 (7), 3156-3163, 2006 | 76 | 2006 |
| Phase ii, randomized, placebo-controlled, 90-day study of emixustat hydrochloride in geographic atrophy associated with dry age-related macular degeneration PU Dugel, RL Novack, KG Csaky, PP Richmond, DG Birch, R Kubota Retina 35 (6), 1173-1183, 2015 | 71 | 2015 |
| Lecithin: retinol acyltransferase is responsible for amidation of retinylamine, a potent inhibitor of the retinoid cycle M Golczak, Y Imanishi, V Kuksa, T Maeda, R Kubota, K Palczewski Journal of Biological Chemistry 280 (51), 42263-42273, 2005 | 68 | 2005 |
| Compositions and methods for diagnosing and treating retinal diseases R Kubota, K Palczewski, A Gall US Patent App. 11/361,027, 2006 | 62 | 2006 |
| Mouse Myocilin (Myoc) Gene Expression in Ocular Tissues1 H Takahashi, S Noda, Y Imamura, A Nagasawa, R Kubota, Y Mashima, ... Biochemical and biophysical research communications 248 (1), 104-109, 1998 | 58 | 1998 |
| Chromosomal mapping of a family of human glutamine synthetase genes: functional gene (GLUL) on 1q25, pseudogene (GLULP) on 9p13, and three related genes (GLULL1, GLULL2, GLULL3 … Y Wang, J Kudoh, R Kubota, S Asakawa, S Minoshima, N Shimizu Genomics 37 (2), 195-199, 1996 | 49 | 1996 |
| Image converting apparatus, image reproducing apparatus, and image converting method K Kobayashi, M Wakamori, H Uwabo, R Kubota, T Suzuki US Patent App. 13/296,614, 2012 | 48 | 2012 |
| Novel mutations in the myocilin gene in Japanese glaucoma patients R Kubota, Y Mashima, Y Ohtake, T Tanino, T Kimura, Y Hotta, A Kanai, ... Human mutation 16 (3), 270-270, 2000 | 48 | 2000 |
| Amine derivative compounds for treating ophthalmic diseases and disorders IL Scott, VA Kuksa, MW Orme, F Hong, TL Little Jr, R Kubota US Patent 8,076,516, 2011 | 45 | 2011 |
