A Norrin/Wnt surrogate antibody stimulates endothelial cell barrier function and rescues retinopathy R Chidiac, M Abedin, G Macleod, A Yang, PE Thibeault, LL Blazer, ... EMBO Molecular Medicine 13 (7), e13977, 2021 | 34 | 2021 |
Targeting a proteinase-activated receptor 4 (PAR4) carboxyl terminal motif to regulate platelet function R Ramachandran, K Mihara, P Thibeault, CM Vanderboor, B Petri, ... Molecular pharmacology 91 (4), 287-295, 2017 | 27 | 2017 |
Molecular basis for activation and biased signaling at the thrombin-activated GPCR proteinase activated receptor-4 (PAR4) PE Thibeault, JC LeSarge, M Fernandes, P Chidiac, PB Stathopulos, ... Journal of Biological Chemistry 295 (8), 2520-2540, 2020 | 25 | 2020 |
Role of the helix-8 and C-terminal tail in regulating proteinase activated receptor 2 signaling PE Thibeault, R Ramachandran ACS Pharmacology & Translational Science 3 (5), 868-882, 2020 | 14 | 2020 |
Proteinase-activated receptor 4 activation triggers cell membrane blebbing through RhoA and β-arrestin CMG Vanderboor, PE Thibeault, KCJ Nixon, R Gros, J Kramer, ... Molecular Pharmacology 97 (6), 365-376, 2020 | 10 | 2020 |
Biased signaling in platelet G-protein coupled receptors PE Thibeault, R Ramachandran Canadian Journal of Physiology and Pharmacology 99 (3), 255-269, 2021 | 9 | 2021 |
High affinity fluorescent probe for proteinase-activated receptor 2 (PAR2) JC LeSarge, P Thibeault, M Milne, R Ramachandran, LG Luyt ACS Medicinal Chemistry Letters 10 (7), 1045-1050, 2019 | 7 | 2019 |
Staphylococcus aureus-serine protease-like protein B (SplB) activates PAR2 and induces endothelial barrier dysfunction A Chandrabalan, PE Thibeault, B Smiljanov, LA Mittmann, ... BioRxiv, 2020.12. 30.424670, 2021 | 3 | 2021 |
Single Amino Acid Replacement in G‐7039 Leads to a 70‐fold Increase in Binding toward GHS‐R1a T Lalonde, MM Fowkes, J Hou, PE Thibeault, M Milne, S Dhanvantari, ... ChemMedChem 14 (20), 1762-1766, 2019 | 3 | 2019 |
Protease-activated receptor 2 (PAR2)-targeting peptide derivatives for positron emission tomography (PET) imaging JC LeSarge, P Thibeault, L Yu, MD Childs, VM Mirka, Q Qi, MS Fox, ... European Journal of Medicinal Chemistry 246, 114989, 2023 | 1 | 2023 |
Regulatory and signalling roles for helix-8 and C-terminal tail residues in the thrombin-activated GPCR, proteinase activated receptor 4 PE Thibeault, V Mirka, R Ramachandran CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY 99 (11), S12-S12, 2021 | | 2021 |
Receptors| Proteinase-Activated Receptors PE Thibeault, MD Hollenberg, R Ramachandran Elsevier, 2021 | | 2021 |
Front Cover: Single Amino Acid Replacement in G‐7039 Leads to a 70‐fold Increase in Binding toward GHS‐R1a (ChemMedChem 20/2019) T Lalonde, MM Fowkes, J Hou, PE Thibeault, M Milne, S Dhanvantari, ... ChemMedChem 14 (20), 1743-1743, 2019 | | 2019 |
Promoting Active Learning in Physiology Lectures Through Student Response Systems: To Click or Not to Click P Thibeault Teaching Innovation Projects 8 (1), 2018 | | 2018 |