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Dylan M Marchione
Dylan M Marchione
Senior Scientist, Servier Pharmaceuticals
Dirección de correo verificada de servier.com
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Human chimeric antigen receptor macrophages for cancer immunotherapy
M Klichinsky, M Ruella, O Shestova, XM Lu, A Best, M Zeeman, ...
Nature biotechnology 38 (8), 947-953, 2020
8622020
The histone mark H3K36me2 recruits DNMT3A and shapes the intergenic DNA methylation landscape
DN Weinberg, S Papillon-Cavanagh, H Chen, Y Yue, X Chen, ...
Nature 573 (7773), 281-286, 2019
3942019
H3K27M induces defective chromatin spread of PRC2-mediated repressive H3K27me2/me3 and is essential for glioma tumorigenesis
AS Harutyunyan, B Krug, H Chen, S Papillon-Cavanagh, M Zeinieh, ...
Nature communications 10 (1), 1262, 2019
2622019
Impaired H3K36 methylation defines a subset of head and neck squamous cell carcinomas
S Papillon-Cavanagh, C Lu, T Gayden, LG Mikael, D Bechet, ...
Nature genetics 49 (2), 180-185, 2017
2332017
Characterization of histone acylations links chromatin modifications with metabolism
J Simithy, S Sidoli, ZF Yuan, M Coradin, NV Bhanu, DM Marchione, ...
Nature communications 8 (1), 1141, 2017
1792017
Pervasive H3K27 acetylation leads to ERV expression and a therapeutic vulnerability in H3K27M gliomas
B Krug, N De Jay, AS Harutyunyan, S Deshmukh, DM Marchione, ...
Cancer cell 35 (5), 782-797. e8, 2019
1752019
EpiProfile 2.0: a computational platform for processing epi-proteomics mass spectrometry data
ZF Yuan, S Sidoli, DM Marchione, J Simithy, KA Janssen, MR Szurgot, ...
Journal of proteome research 17 (7), 2533-2541, 2018
1362018
Histone H3. 3G34-mutant interneuron progenitors co-opt PDGFRA for gliomagenesis
CCL Chen, S Deshmukh, S Jessa, D Hadjadj, V Lisi, AF Andrade, D Faury, ...
Cell 183 (6), 1617-1633. e22, 2020
1132020
Histone H3. 3 G34 mutations promote aberrant PRC2 activity and drive tumor progression
SU Jain, S Khazaei, DM Marchione, SM Lundgren, X Wang, DN Weinberg, ...
Proceedings of the National Academy of Sciences 117 (44), 27354-27364, 2020
652020
H3K27M in gliomas causes a one-step decrease in H3K27 methylation and reduced spreading within the constraints of H3K36 methylation
AS Harutyunyan, H Chen, T Lu, C Horth, H Nikbakht, B Krug, C Russo, ...
Cell reports 33 (7), 2020
572020
Glutathione antioxidant pathway activity and reserve determine toxicity and specificity of the biliary toxin biliatresone in zebrafish
X Zhao, K Lorent, BJ Wilkins, DM Marchione, K Gillespie, ...
Hepatology 64 (3), 894-907, 2016
562016
H3. 3 G34W promotes growth and impedes differentiation of osteoblast-like mesenchymal progenitors in giant cell tumor of bone
S Khazaei, N De Jay, S Deshmukh, LD Hendrikse, W Jawhar, CCL Chen, ...
Cancer discovery 10 (12), 1968-1987, 2020
532020
Histone H3.3 beyond cancer: Germline mutations in Histone 3 Family 3A and 3B cause a previously unidentified neurodegenerative disorder in 46 patients
L Bryant, D Li, SG Cox, D Marchione, EF Joiner, K Wilson, K Janssen, ...
Science advances 6 (49), eabc9207, 2020
522020
Chromatin-mediated alternative splicing regulates cocaine-reward behavior
SJ Xu, SI Lombroso, DK Fischer, MD Carpenter, DM Marchione, ...
Neuron 109 (18), 2943-2966. e8, 2021
452021
HYPERsol: High-quality data from archival FFPE tissue for clinical proteomics
DM Marchione, I Ilieva, K Devins, D Sharpe, DJ Pappin, BA Garcia, ...
Journal of proteome research 19 (2), 973-983, 2020
452020
Epigenomic reordering induced by polycomb loss drives oncogenesis but leads to therapeutic vulnerabilities in malignant peripheral nerve sheath tumors
JB Wojcik, DM Marchione, S Sidoli, A Djedid, A Lisby, J Majewski, ...
Cancer research 79 (13), 3205-3219, 2019
452019
Histone H3K27 dimethyl loss is highly specific for malignant peripheral nerve sheath tumor and distinguishes true PRC2 loss from isolated H3K27 trimethyl loss
DM Marchione, A Lisby, AN Viaene, M Santi, ML Nasrallah, LP Wang, ...
Modern Pathology 32 (10), 1434-1446, 2019
402019
Preferential phosphorylation on old histones during early mitosis in human cells
S Lin, ZF Yuan, Y Han, DM Marchione, BA Garcia
Journal of Biological Chemistry 291 (29), 15342-15357, 2016
332016
Multicenter Phase I Trial of Ivosidenib as Maintenance Treatment Following Allogeneic Hematopoietic Cell Transplantation for IDH1-Mutated Acute Myeloid Leukemia
AT Fathi, HT Kim, RJ Soiffer, MJ Levis, S Li, AS Kim, Z DeFilipp, ...
Clinical Cancer Research 29 (11), 2034-2042, 2023
112023
Proteomic approaches for cancer epigenetics research
DM Marchione, BA Garcia, J Wojcik
Expert review of proteomics 16 (1), 33-47, 2019
92019
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Artículos 1–20