| Nodal/Activin signaling drives self-renewal and tumorigenicity of pancreatic cancer stem cells and provides a target for combined drug therapy E Lonardo, PC Hermann, MT Mueller, S Huber, A Balic, ... Cell stem cell 9 (5), 433-446, 2011 | 448 | 2011 |
| Intracellular autofluorescence: a biomarker for epithelial cancer stem cells I Miranda-Lorenzo, J Dorado, E Lonardo, S Alcala, AG Serrano, ... Nature methods 11 (11), 1161-1169, 2014 | 220 | 2014 |
| Microenvironmental hCAP-18/LL-37 promotes pancreatic ductal adenocarcinoma by activating its cancer stem cell compartment B Sainz, S Alcala, E Garcia, Y Sanchez-Ripoll, MM Azevedo, M Cioffi, ... Gut 64 (12), 1921-1935, 2015 | 141 | 2015 |
| The Ever-Evolving Concept of the Cancer Stem Cell in Pancreatic Cancer S Valle, L Martin-Hijano, S Alcalá, M Alonso-Nocelo, B Sainz Jr Cancers 10 (2), 33, 2018 | 132 | 2018 |
| Combination of injectable multiple growth factor–releasing scaffolds and cell therapy as an advanced modality to enhance tissue neovascularization J Saif, TM Schwarz, DYS Chau, J Henstock, P Sami, SF Leicht, ... Arteriosclerosis, thrombosis, and vascular biology 30 (10), 1897-1904, 2010 | 116 | 2010 |
| Mitochondrial apoptosis induced by BH3‐only molecules in the exclusive presence of endoplasmic reticular Bak M Klee, K Pallauf, S Alcala, A Fleischer, FX Pimentel‐Muiños The EMBO journal 28 (12), 1757-1768, 2009 | 110 | 2009 |
| A high-throughput screening for mammalian cell death effectors identifies the mitochondrial phosphate carrier as a regulator of cytochrome c release S Alcalá, M Klee, J Fernández, A Fleischer, FX Pimentel-Muiños Oncogene 27 (1), 44-54, 2008 | 110 | 2008 |
| DNMT1 inhibition reprograms pancreatic cancer stem cells via upregulation of the miR-17-92 cluster S Zagorac, S Alcala, G Fernandez Bayon, T Bou Kheir, M Schoenhals, ... Cancer research 76 (15), 4546-4558, 2016 | 109 | 2016 |
| Exploiting oxidative phosphorylation to promote the stem and immunoevasive properties of pancreatic cancer stem cells S Valle, S Alcalá, L Martin-Hijano, P Cabezas-Sáinz, D Navarro, ... Nature Communications 11 (1), 5265, 2020 | 89 | 2020 |
| ISG15 and ISGylation is required for pancreatic cancer stem cell mitophagy and metabolic plasticity S Alcalá, P Sancho, P Martinelli, D Navarro, C Pedrero, L Martín-Hijano, ... Nature Communications 11 (1), 2682, 2020 | 77 | 2020 |
| Tumor-associated macrophage-secreted 14-3-3ζ signals via AXL to promote pancreatic cancer chemoresistance G D’Errico, M Alonso-Nocelo, M Vallespinos, PC Hermann, S Alcalá, ... Oncogene 38 (27), 5469-5485, 2019 | 66 | 2019 |
| Glutathione metabolism is essential for self-renewal and chemoresistance of pancreatic cancer stem cells P Jagust, S Alcalá, B Sainz Jr, C Heeschen, P Sancho World Journal of Stem Cells 12 (11), 1410-1428, 2020 | 49 | 2020 |
| The ever-changing landscape of pancreatic cancer stem cells P Sancho, S Alcala, V Usachov, PC Hermann, B Sainz Jr Pancreatology 16 (4), 489-496, 2016 | 39 | 2016 |
| Inhibition of mitochondrial dynamics preferentially targets pancreatic cancer cells with enhanced tumorigenic and invasive potential S Courtois, B de Luxán-Delgado, L Penin-Peyta, A Royo-García, ... Cancers 13 (4), 698, 2021 | 34 | 2021 |
| Targeting MAD2 modulates stemness and tumorigenesis in human Gastric Cancer cell lines N Pajuelo-Lozano, S Alcalá, B Sainz Jr, R Perona, I Sanchez-Perez Theranostics 10 (21), 9601, 2020 | 34 | 2020 |
| Dysregulated splicing factor SF3B1 unveils a dual therapeutic vulnerability to target pancreatic cancer cells and cancer stem cells with an anti-splicing drug E Alors-Perez, R Blázquez-Encinas, S Alcalá, C Viyuela-García, ... Journal of Experimental & Clinical Cancer Research 40 (1), 1-21, 2021 | 27 | 2021 |
| Macrophages direct cancer cells through a LOXL2-mediated metastatic cascade in pancreatic ductal adenocarcinoma M Alonso-Nocelo, L Ruiz-Cañas, P Sancho, K Görgülü, S Alcalá, ... Gut 72 (2), 345-359, 2023 | 25 | 2023 |
| Targeting SRC Kinase Signaling in Pancreatic Cancer Stem Cells S Alcalá, V Mayoral-Varo, L Ruiz-Cañas, JC López-Gil, C Heeschen, ... International journal of molecular sciences 21 (20), 7437, 2020 | 23 | 2020 |
| A label free disposable device for rapid isolation of rare tumor cells from blood by ultrasounds I González, J Earl, LJ Fernández, B Sainz, A Pinto, R Monge, S Alcalá, ... Micromachines 9 (3), 129, 2018 | 18 | 2018 |
| The Anthrax Toxin Receptor 1 (ANTXR1) Is Enriched in Pancreatic Cancer Stem Cells Derived from Primary Tumor Cultures S Alcalá, P Martinelli, PC Hermann, C Heeschen, B Sainz Stem cells international 2019, 2019 | 17 | 2019 |
Bruno Sainz, Jr.Instituto de Investigaciones Biomédicas "Alberto Sols" CSIC-UAMVerified email at iib.uam.es
