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Hans Lennernäs
Hans Lennernäs
Department of Pharmaceutical Bioscience, Uppsala University
Verified email at farmbio.uu.se
Title
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Cited by
Year
A theoretical basis for a biopharmaceutic drug classification: the correlation of in vitro drug product dissolution and in vivo bioavailability
GL Amidon, H Lennernäs, VP Shah, JR Crison
Pharmaceutical research 12 (3), 413-420, 1995
73091995
Molecular properties of WHO essential drugs and provisional biopharmaceutical classification
NA Kasim, M Whitehouse, C Ramachandran, M Bermejo, H Lennernäs, ...
Molecular pharmaceutics 1 (1), 85-96, 2004
10592004
Pharmacodynamics and pharmacokinetics of the HMG-CoA reductase inhibitors
H Lennernäs, G Fager
Clinical pharmacokinetics 32 (5), 403-425, 1997
7531997
Clinical pharmacokinetics of atorvastatin
H Lennernäs
Clinical pharmacokinetics 42 (13), 1141-1160, 2003
7242003
Coexistence of passive and carrier-mediated processes in drug transport
K Sugano, M Kansy, P Artursson, A Avdeef, S Bendels, L Di, GF Ecker, ...
Nature reviews Drug discovery 9 (8), 597-614, 2010
7002010
Comparison between permeability coefficients in rat and human jejunum
U Fagerholm, M Johansson, H Lennernäs
Pharmaceutical research 13 (9), 1336-1342, 1996
6191996
Correlation of human jejunal permeability (in vivo) of drugs with experimentally and theoretically derived parameters. A multivariate data analysis approach
S Winiwarter, NM Bonham, F Ax, A Hallberg, H Lennernäs, A Karlén
Journal of medicinal chemistry 41 (25), 4939-4949, 1998
5511998
Characterization of fluids from the stomach and proximal jejunum in men and women
A Lindahl, AL Ungell, L Knutson, H Lennernäs
Pharmaceutical research 14 (4), 497-502, 1997
4791997
Improved cortisol exposure-time profile and outcome in patients with adrenal insufficiency: a prospective randomized trial of a novel hydrocortisone dual-release formulation
G Johannsson, AG Nilsson, R Bergthorsdottir, P Burman, P Dahlqvist, ...
The Journal of Clinical Endocrinology & Metabolism 97 (2), 473-481, 2012
3512012
Comparison between active and passive drug transport in human intestinal epithelial (Caco-2) cells in vitro and human jejunum in vivo
H Lennernäs, K Palm, U Fagerholm, P Artursson
International journal of pharmaceutics 127 (1), 103-107, 1996
3371996
Membrane transport of drugs in different regions of the intestinal tract of the rat
AL Ungell, S Nylander, S Bergstrand, Å Sjöberg, H Lennernäs
Journal of pharmaceutical sciences 87 (3), 360-366, 1998
3301998
The effects of food on the dissolution of poorly soluble drugs in human and in model small intestinal fluids
EM Persson, AS Gustafsson, AS Carlsson, RG Nilsson, L Knutson, ...
Pharmaceutical research 22 (12), 2141-2151, 2005
3132005
Intestinal permeability and its relevance for absorption and elimination
H Lennernäs
Xenobiotica 37 (10-11), 1015-1051, 2007
3052007
In vivo methods for drug absorption–comparative physiologies, model selection, correlations with in vitro methods (IVIVC), and applications for formulation/API/excipient …
E Sjögren, B Abrahamsson, P Augustijns, D Becker, MB Bolger, ...
European Journal of Pharmaceutical Sciences 57, 99-151, 2014
2982014
Optimizing levodopa pharmacokinetics: intestinal infusion versus oral sustained-release tablets
D Nyholm, H Askmark, C Gomes–Trolin, T Knutson, H Lennernäs, ...
Clinical neuropharmacology 26 (3), 156-163, 2003
2982003
Chitosans as absorption enhancers of poorly absorbable drugs: 3: Influence of mucus on absorption enhancement
NGM Schipper, KM Vårum, P Stenberg, G Ocklind, H Lennernäs, ...
European journal of pharmaceutical sciences 8 (4), 335-343, 1999
2911999
Regional jejunal perfusion, a new in vivo approach to study oral drug absorption in man
H Lennernäs, Ö Ahrenstedt, R Hällgren, L Knutson, M Ryde, LK Paalzow
Pharmaceutical research 9 (10), 1243-1251, 1992
2911992
The use of biopharmaceutic classification of drugs in drug discovery and development: current status and future extension
H Lennernäs, B Abrahamsson
Journal of pharmacy and pharmacology 57 (3), 273-285, 2005
2892005
Human jejunal effective permeability and its correlation with preclinical drug absorption models
H LennernÄs
Journal of Pharmacy and Pharmacology 49 (7), 627-638, 1997
2801997
Gene and protein expression of P-glycoprotein, MRP1, MRP2, and CYP3A4 in the small and large human intestine
S Berggren, C Gall, N Wollnitz, M Ekelund, U Karlbom, J Hoogstraate, ...
Molecular pharmaceutics 4 (2), 252-257, 2007
2432007
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