FRET biosensor uncovers cAMP nano-domains at β-adrenergic targets that dictate precise tuning of cardiac contractility NC Surdo, M Berrera, A Koschinski, M Brescia, MR Machado, C Carr, ... Nature communications 8 (1), 15031, 2017 | 191 | 2017 |
An essential cell-autonomous role for hepcidin in cardiac iron homeostasis S Lakhal-Littleton, M Wolna, YJ Chung, HC Christian, LC Heather, ... Elife 5, e19804, 2016 | 179 | 2016 |
Modulation of compartmentalised cyclic nucleotide signalling via local inhibition of phosphodiesterase activity M Brescia, M Zaccolo International journal of molecular sciences 17 (10), 1672, 2016 | 59 | 2016 |
Expanding the editable genome and CRISPR–Cas9 versatility using DNA cutting-free gene targeting based on in trans paired nicking X Chen, F Tasca, Q Wang, J Liu, JM Janssen, MD Brescia, M Bellin, ... Nucleic Acids Research 48 (2), 974-995, 2020 | 30 | 2020 |
High-Capacity Adenoviral Vectors Permit Robust and Versatile Testing of DMD Gene Repair Tools and Strategies in Human Cells M Brescia, JM Janssen, J Liu, MAFV Gonçalves Cells 9 (4), 869, 2020 | 23 | 2020 |
Phosphodiesterase 2A as a therapeutic target to restore cardiac neurotransmission during sympathetic hyperactivity K Liu, D Li, G Hao, D McCaffary, O Neely, L Woodward, D Ioannides, ... JCI insight 3 (9), 2018 | 23 | 2018 |
Adenoviral transduction of FRET-based biosensors for cAMP in primary adult mouse cardiomyocytes O Lomas, M Brescia, R Carnicer, S Monterisi, NC Surdo, M Zaccolo cAMP Signaling: Methods and Protocols, 103-115, 2015 | 14 | 2015 |
FRET biosensor uncovers cAMP nano-domains at β-adrenergic targets that dictate precise tuning of cardiac contractility. Nat Commun 8: 15031 NC Surdo, M Berrera, A Koschinski, M Brescia, MR Machado, C Carr, ... | 13 | 2017 |
Vascularized hiPSC-derived 3D cardiac microtissue on chip U Arslan, M Brescia, V Meraviglia, DM Nahon, RWJ van Helden, JM Stein, ... Stem cell reports 18 (7), 1394-1404, 2023 | 12 | 2023 |
Large-scale genome editing based on high-capacity adenovectors and CRISPR-Cas9 nucleases rescues full-length dystrophin synthesis in DMD muscle cells F Tasca, M Brescia, Q Wang, J Liu, JM Janssen, K Szuhai, ... Nucleic Acids Research 50 (13), 7761-7782, 2022 | 11 | 2022 |
Multi-Compartment, Early Disruption of cGMP and cAMP Signalling in Cardiac Myocytes from the mdx Model of Duchenne Muscular Dystrophy M Brescia, YC Chao, A Koschinski, J Tomek, M Zaccolo International Journal of Molecular Sciences 21 (19), 7056, 2020 | 9 | 2020 |
Increase in Ca2+ current by sustained cAMP levels enhances proliferation rate in GH3 cells AL Rodrigues, M Brescia, A Koschinski, TH Moreira, RT Cameron, ... Life sciences 192, 144-150, 2018 | 9 | 2018 |
An essential cell-autonomous role for hepcidin in cardiac iron homeostasis. Elife 5 S Lakhal-Littleton, M Wolna, YJ Chung, HC Christian, LC Heather, ... | 9 | 2016 |
High-capacity adenovector delivery of forced CRISPR-Cas9 heterodimers fosters precise chromosomal deletions in human cells F Tasca, M Brescia, J Liu, JM Janssen, K Mamchaoui, MAFV Gonçalves Molecular Therapy-Nucleic Acids 31, 746-762, 2023 | 3 | 2023 |
ETV2 upregulation marks the specification of early cardiomyocytes and endothelial cells during co-differentiation X Cao, M Mircea, GK Yakala, FE van den Hil, M Brescia, H Mei, ... Stem Cells 41 (2), 140-152, 2023 | 2 | 2023 |
Increasing efficiency of alveolar type II cells generation from human induced pluripotent stem cells AR Ruiz, A Ravi, S Khoenkhoen, MD Brescia, B Van Meer, R Olmer, ... European Respiratory Journal 60 (suppl 66), 2022 | | 2022 |
Multi-compartment, early disruption of cGMP and cAMP signalling in cardiac myocytes from the mdx model of Duchenne Muscular Dystrophy M Brescia, YC Chao, A Koschinski, J Tomek, M Zaccolo International Journal of Molecular Sciences 21 (19), 2020 | | 2020 |
Increase in Ca2+ current by sustained cAMP levels enhances proliferation rate in GH3 cells M Brescia, A Koschinski, RT Cameron, G Baillie, M Zaccolo, JS Cruz Life sciences 192 (2), 2018 | | 2018 |
204 The cardiac hepcidin/ferroportin axis is essntial for cardiac iron homeostasis and function S Lakhal-Littleton, M Wolna, YJ Chung, H Christian, L Heather, M Brescia, ... Heart 103 (Suppl 5), A137-A137, 2017 | | 2017 |
Cyclic nucleotide signalling in cardiac myocytes from the mdx model of Duchenne muscular dystrophy M Brescia University of Oxford, 2017 | | 2017 |