Short-range exosomal transfer of viral RNA from infected cells to plasmacytoid dendritic cells triggers innate immunity M Dreux, U Garaigorta, B Boyd, E Décembre, J Chung, C Whitten-Bauer, ... Cell host & microbe 12 (4), 558-570, 2012 | 530 | 2012 |
Plasmacytoid dendritic cells sense hepatitis C virus–infected cells, produce interferon, and inhibit infection K Takahashi, S Asabe, S Wieland, U Garaigorta, P Gastaminza, ... Proceedings of the National Academy of Sciences 107 (16), 7431-7436, 2010 | 325 | 2010 |
Hepatitis C virus blocks interferon effector function by inducing protein kinase R phosphorylation U Garaigorta, FV Chisari Cell host & microbe 6 (6), 513-522, 2009 | 278 | 2009 |
Hepatitis C virus (HCV) induces formation of stress granules whose proteins regulate HCV RNA replication and virus assembly and egress U Garaigorta, MH Heim, B Boyd, S Wieland, FV Chisari Journal of virology 86 (20), 11043-11056, 2012 | 125 | 2012 |
COVID-19 vaccine candidates based on modified vaccinia virus Ankara expressing the SARS-CoV-2 spike protein induce robust T-and B-cell immune responses and full efficacy in mice J García-Arriaza, U Garaigorta, P Pérez, A Lázaro-Frías, C Zamora, ... Journal of virology 95 (7), 10.1128/jvi. 02260-20, 2021 | 93 | 2021 |
Mutation analysis of a recombinant NS replicon shows that influenza virus NS1 protein blocks the splicing and nucleo-cytoplasmic transport of its own viral mRNA U Garaigorta, J Ortín Nucleic acids research 35 (14), 4573-4582, 2007 | 83 | 2007 |
HBsAg-redirected T cells exhibit antiviral activity in HBV-infected human liver chimeric mice RL Kruse, T Shum, H Tashiro, M Barzi, Z Yi, C Whitten-Bauer, X Legras, ... Cytotherapy 20 (5), 697-705, 2018 | 80 | 2018 |
Genetic analysis of influenza virus NS1 gene: a temperature-sensitive mutant shows defective formation of virus particles U Garaigorta, AM Falcón, J Ortín Journal of virology 79 (24), 15246-15257, 2005 | 61 | 2005 |
In vivo reduction of hepatitis B virus antigenemia and viremia by antisense oligonucleotides G Billioud, RL Kruse, M Carrillo, C Whitten-Bauer, D Gao, A Kim, L Chen, ... Journal of Hepatology 64 (4), 781-789, 2016 | 60 | 2016 |
Emergent properties of the interferon-signalling network may underlie the success of hepatitis C treatment P Padmanabhan, U Garaigorta, NM Dixit Nature Communications 5 (1), 3872, 2014 | 40 | 2014 |
Hepatitis B virus and DNA damage response: Interactions and consequences for the infection A Gómez-Moreno, U Garaigorta Viruses 9 (10), 304, 2017 | 37 | 2017 |
Aberrant integration of Hepatitis B virus DNA promotes major restructuring of human hepatocellular carcinoma genome architecture EG Álvarez, J Demeulemeester, P Otero, C Jolly, D García-Souto, ... Nature communications 12 (1), 6910, 2021 | 28 | 2021 |
Antiviral drugs targeting endosomal membrane proteins inhibit distant animal and human pathogenic viruses I Galindo, U Garaigorta, F Lasala, MA Cuesta-Geijo, P Bueno, C Gil, ... Antiviral research 186, 104990, 2021 | 27 | 2021 |
The bacterial mucosal immunotherapy MV130 protects against SARS-CoV-2 infection and improves COVID-19 vaccines immunogenicity C Del Fresno, J García-Arriaza, S Martínez-Cano, I Heras-Murillo, ... Frontiers in Immunology 12, 748103, 2021 | 26 | 2021 |
Host-directed FDA-approved drugs with antiviral activity against SARS-CoV-2 identified by hierarchical in silico/in vitro screening methods T Ginex, U Garaigorta, D Ramírez, V Castro, V Nozal, I Maestro, ... Pharmaceuticals 14 (4), 332, 2021 | 26 | 2021 |
Identification of Niemann-Pick C1 protein as a potential novel SARS-CoV-2 intracellular target I García-Dorival, MÁ Cuesta-Geijo, L Barrado-Gil, I Galindo, U Garaigorta, ... Antiviral Research 194, 105167, 2021 | 20 | 2021 |
Nanobodies protecting from lethal SARS-CoV-2 infection target receptor binding epitopes preserved in virus variants other than omicron JM Casasnovas, Y Margolles, MA Noriega, M Guzmán, R Arranz, ... Frontiers in Immunology 13, 863831, 2022 | 12 | 2022 |
SARS-CoV-2 fears green: the chlorophyll catabolite Pheophorbide a is a potent antiviral GH Jimenez-Aleman, V Castro, A Londaitsbehere, M Gutierrez-Rodríguez, ... Pharmaceuticals 14 (10), 1048, 2021 | 11 | 2021 |
The host factor erlin-1 is required for efficient hepatitis C virus infection C Whitten-Bauer, J Chung, A Gómez-Moreno, P Gomollón-Zueco, ... Cells 8 (12), 1555, 2019 | 9 | 2019 |
Structure and inhibition of SARS-CoV-1 and SARS-CoV-2 main proteases by oral antiviral compound AG7404 M Fàbrega-Ferrer, A Herrera-Morandé, S Muriel-Goñi, J Pérez-Saavedra, ... Antiviral Research 208, 105458, 2022 | 8 | 2022 |