Selective activity of polyene macrolides produced by genetically modified Streptomyces on Trypanosoma cruzi M Rolón, EM Seco, C Vega, JJ Nogal, JA Escario, A Gómez-Barrio, ... International Journal of Antimicrobial Agents 28 (2), 104-109, 2006 | 87 | 2006 |
Starter unit choice determines the production of two tetraene macrolides, rimocidin and CE-108, in Streptomyces diastaticus var. 108 EM Seco, FJ Pérez-Zúñiga, MS Rolón, F Malpartida Chemistry & biology 11 (3), 357-366, 2004 | 75 | 2004 |
Two polyene amides produced by genetically modified Streptomyces diastaticus var. 108 EM Seco, T Cuesta, S Fotso, H Laatsch, F Malpartida Chemistry & biology 12 (5), 535-543, 2005 | 47 | 2005 |
CE-108, a new macrolide tetraene antibiotic FJ Perez-Zuniga, EM Seco, T Cuesta, F Degenhardt, J Rohr, C Vallin, ... The Journal of antibiotics 57 (3), 197-204, 2004 | 35 | 2004 |
Bacillus subtilis RecA and its accessory factors, RecF, RecO, RecR and RecX, are required for spore resistance to DNA double-strand break I Vlašić, R Mertens, EM Seco, B Carrasco, S Ayora, G Reitz, ... Nucleic acids research 42 (4), 2295-2307, 2014 | 31 | 2014 |
Bacillus subtilis DisA helps to circumvent replicative stress during spore revival M Raguse, R Torres, EM Seco, C Gándara, S Ayora, R Moeller, JC Alonso DNA repair 59, 57-68, 2017 | 27 | 2017 |
Bacillus subtilis DNA polymerases, PolC and DnaE, are required for both leading and lagging strand synthesis in SPP1 origin-dependent DNA replication EM Seco, S Ayora Nucleic acids research 45 (14), 8302-8313, 2017 | 26 | 2017 |
Bacteriophage SPP1 DNA replication strategies promote viral and disable host replication in vitro EM Seco, JC Zinder, CM Manhart, A Lo Piano, CS McHenry, S Ayora Nucleic acids research 41 (3), 1711-1721, 2013 | 26* | 2013 |
A tailoring activity is responsible for generating polyene amide derivatives in Streptomyces diastaticus var. 108 EM Seco, S Fotso, H Laatsch, F Malpartida Chemistry & biology 12 (10), 1093-1101, 2005 | 24 | 2005 |
New Rimocidin/CE-108 Derivatives Obtained by a Crotonyl-CoA Carboxylase/Reductase Gene Disruption in Streptomyces diastaticus var. 108: Substrates for the … L Escudero, M Al-Refai, C Nieto, H Laatsch, F Malpartida, EM Seco PLoS One 10 (8), e0135891, 2015 | 17 | 2015 |
Initiation of polyene macrolide biosynthesis: interplay between polyketide synthase domains and modules as revealed via domain swapping, mutagenesis, and heterologous … S Heia, SEF Borgos, H Sletta, L Escudero, EM Seco, F Malpartida, ... Applied and environmental microbiology 77 (19), 6982-6990, 2011 | 15 | 2011 |
Bacillus subtilis RarA modulates replication restart B Carrasco, EM Seco, M López-Sanz, JC Alonso, S Ayora Nucleic Acids Research 46 (14), 7206-7220, 2018 | 13 | 2018 |
The pcsA gene from Streptomyces diastaticus var. 108 encodes a polyene carboxamide synthase with broad substrate specificity for polyene amides biosynthesis EM Seco, D Miranzo, C Nieto, F Malpartida Applied microbiology and biotechnology 85, 1797-1807, 2010 | 13 | 2010 |
Differential trypanocidal activity of novel macrolide antibiotics; correlation to genetic lineage C Aquilino, ML Gonzalez Rubio, EM Seco, L Escudero, L Corvo, M Soto, ... Public Library of Science 7 (7), e40901, 2012 | 11 | 2012 |
Efficient markerless integration of genes in the chromosome of probiotic E. coli Nissle 1917 by bacterial conjugation EM Seco, LÁ Fernández Microbial Biotechnology 15 (5), 1374-1391, 2022 | 9 | 2022 |
Isolation and characterization of pcsB, the gene for a polyene carboxamide synthase that tailors pimaricin into AB-400 D Miranzo, EM Seco, T Cuesta, F Malpartida Applied microbiology and biotechnology 85, 1809-1819, 2010 | 8 | 2010 |
Synthetic bacteria with programmed cell targeting and protein injection suppress tumor growth in vivo A Asensio-Calavia, C Manas, A Cabrera-Fisac, E Pico-Sanchez, EM Seco, ... bioRxiv, 2024.04. 22.590337, 2024 | | 2024 |
Dynamics of DNA double-strand break repair in Bacillus subtilis B Carrasco, PP Cárdenas, E Serrano, R Torres, EM Seco, S Ayora, ... Caister Academic Press, 2017 | | 2017 |
DNA Replication Initiation Studied at the Single Molecule Level HM Cheng, P Gröger, A Hartmann, EM Seco, S Ayora, M Schlierf Biophysical Journal 104 (2), 74a, 2013 | | 2013 |
Contenido-Contents JM Abelairas, A Perera, JM Guardiola, C Morales Romo, PH Villarejo, ... Archivos de la Sociedad Española de Oftalmología 59 (4), 385-392, 1990 | | 1990 |