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Michael Carty
Michael Carty
Verified email at tcd.ie
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Year
The human adaptor SARM negatively regulates adaptor protein TRIF–dependent Toll-like receptor signaling
M Carty, R Goodbody, M Schröder, J Stack, PN Moynagh, AG Bowie
Nature immunology 7 (10), 1074-1081, 2006
6972006
BRCA1 functions as a differential modulator of chemotherapy-induced apoptosis
JE Quinn, RD Kennedy, PB Mullan, PM Gilmore, M Carty, PG Johnston, ...
Cancer research 63 (19), 6221-6228, 2003
5892003
Detection of viral infections by innate immunity
M Carty, C Guy, AG Bowie
Biochemical pharmacology 183, 114316, 2021
2942021
Evaluating the role of Toll-like receptors in diseases of the central nervous system
M Carty, AG Bowie
Biochemical pharmacology 81 (7), 825-837, 2011
1962011
Recent insights into the role of Toll-like receptors in viral infection
M Carty, AG Bowie
Clinical & Experimental Immunology 161 (3), 397-406, 2010
1522010
Cell survival and cytokine release after inflammasome activation is regulated by the Toll-IL-1R protein SARM
M Carty, J Kearney, KA Shanahan, E Hams, R Sugisawa, D Connolly, ...
Immunity 50 (6), 1412-1424. e6, 2019
1212019
Phosphorylation of caldesmon by ERK MAP kinases in smooth muscle
JC Hedges, BC Oxhorn, M Carty, LP Adam, IA Yamboliev, WT Gerthoffer
American Journal of Physiology-Cell Physiology 278 (4), C718-C726, 2000
1212000
Innate antiviral signalling in the central nervous system
M Carty, L Reinert, SR Paludan, AG Bowie
Trends in immunology 35 (2), 79-87, 2014
752014
BRCA1 interacts with and is required for paclitaxel-induced activation of mitogen-activated protein kinase kinase kinase 3
PM Gilmore, N McCabe, JE Quinn, RD Kennedy, JJ Gorski, HN Andrews, ...
Cancer research 64 (12), 4148-4154, 2004
632004
Coupling of M2 muscarinic receptors to ERK MAP kinases and caldesmon phosphorylation in colonic smooth muscle
AK Cook, M Carty, CA Singer, IA Yamboliev, WT Gerthoffer
American Journal of Physiology-Gastrointestinal and Liver Physiology 278 (3 …, 2000
502000
SARM: From immune regulator to cell executioner
M Carty, AG Bowie
Biochemical pharmacology 161, 52-62, 2019
472019
SARM1 deficiency promotes rod and cone photoreceptor cell survival in a model of retinal degeneration
E Ozaki, L Gibbons, NGB Neto, P Kenna, M Carty, M Humphries, ...
Life science alliance 3 (5), 2020
462020
Dual NADPH oxidases DUOX1 and DUOX2 synthesize NAADP and are necessary for Ca2+ signaling during T cell activation
F Gu, A Krüger, HG Roggenkamp, R Alpers, D Lodygin, V Jaquet, F Möckl, ...
Science signaling 14 (709), eabe3800, 2021
332021
SARM regulates CCL5 production in macrophages by promoting the recruitment of transcription factors and RNA polymerase II to the Ccl5 promoter
C Gürtler, M Carty, J Kearney, SA Schattgen, A Ding, KA Fitzgerald, ...
The Journal of Immunology 192 (10), 4821-4832, 2014
322014
Poxviral protein E3–altered cytokine production reveals that DExD/H-box helicase 9 controls Toll-like receptor–stimulated immune responses
A Dempsey, SE Keating, M Carty, AG Bowie
Journal of Biological Chemistry 293 (39), 14989-15001, 2018
222018
Role played by BRCA1 in regulating the cellular response to stress
PM Gilmore, JE Quinn, PB Mullan, HN Andrews, N McCabe, M Carty, ...
Biochemical Society Transactions 31 (1), 257-262, 2003
222003
Alum activates the bovine NLRP3 inflammasome
C Harte, AL Gorman, S McCluskey, M Carty, AG Bowie, CJ Scott, ...
Frontiers in Immunology 8, 1494, 2017
212017
SARM1 ablation is protective and preserves spatial vision in an in vivo mouse model of retinal ganglion cell degeneration
LK Finnegan, N Chadderton, PF Kenna, A Palfi, M Carty, AG Bowie, ...
International Journal of Molecular Sciences 23 (3), 1606, 2022
152022
Dimethyl fumarate and 4-octyl itaconate are anticoagulants that suppress Tissue Factor in macrophages via inhibition of Type I Interferon
TAJ Ryan, A Hooftman, AM Rehill, MD Johansen, ECO Brien, ...
Nature Communications 14 (1), 3513, 2023
142023
CRISPR/Cas9-mediated SARM1 knockout and epitope-tagged mice reveal that SARM1 does not regulate nuclear transcription, but is expressed in macrophages
CG Doran, R Sugisawa, M Carty, F Roche, C Fergus, K Hokamp, VP Kelly, ...
Journal of Biological Chemistry 297 (6), 2021
132021
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