Ubl4A is required for insulin-induced Akt plasma membrane translocation through promotion of Arp2/3-dependent actin branching Y Zhao, Y Lin, H Zhang, A Mañas, W Tang, Y Zhang, D Wu, A Lin, J Xiang Proceedings of the National Academy of Sciences 112 (31), 9644-9649, 2015 | 45 | 2015 |
Baxδ2 promotes apoptosis through caspase-8 activation in microsatellite-unstable colon cancer H Zhang, Y Lin, A Manas, Y Zhao, MF Denning, L Ma, J Xiang Molecular Cancer Research 12 (9), 1225-1232, 2014 | 25 | 2014 |
Therapeutic targeting of KSP in preclinical models of high-risk neuroblastoma K Hansson, K Radke, K Aaltonen, J Saarela, A Mañas, J Sjölund, E Smith, ... Science Translational Medicine 12 (562), 2020 | 24 | 2020 |
The functional domains for Bax∆2 aggregate-mediated caspase 8-dependent cell death A Mañas, S Wang, A Nelson, J Li, Y Zhao, H Zhang, A Davis, B Xie, ... Experimental cell research 359 (2), 342-355, 2017 | 16 | 2017 |
Clinically relevant treatment of PDX models reveals patterns of neuroblastoma chemoresistance A Mañas, K Aaltonen, N Andersson, K Hansson, A Adamska, A Seger, ... Science Advances 8 (43), eabq4617, 2022 | 15 | 2022 |
Engineering human mini-bones for the standardized modeling of healthy hematopoiesis, leukemia, and solid tumor metastasis A Grigoryan, D Zacharaki, A Balhuizen, CRM Côme, AG Garcia, ... Science translational medicine 14 (666), eabm6391, 2022 | 12 | 2022 |
BaxΔ2 sensitizes colorectal cancer cells to proteasome inhibitor-induced cell death A Mañas, W Chen, A Nelson, Q Yao, J Xiang Biochemical and biophysical research communications 496 (1), 18-24, 2018 | 10 | 2018 |
Deficiency in ubiquitin-like protein Ubl4A impairs migration of fibroblasts and macrophages Y Zhao, H Zhang, C Affonso, R Bonomo, A Mañas, J Xiang Biochemical and biophysical research communications 483 (1), 617-623, 2017 | 10 | 2017 |
Patient-derived models: Advanced tools for precision medicine in neuroblastoma K Aaltonen, K Radke, A Adamska, A Seger, A Mañas, D Bexell Frontiers in Oncology 12, 1085270, 2023 | 8 | 2023 |
Immunohistochemical detection of the pro-apoptotic Bax∆2 protein in human tissues A Mañas, Q Yao, A Davis, S Basheer, E Beatty, H Zhang, J Li, A Nelson, ... Histochemistry and Cell Biology, 1-13, 2020 | 7 | 2020 |
Detection of pro-apoptotic Bax∆ 2 proteins in the human cerebellum A Mañas, A Davis, S Lamerand, J Xiang Histochemistry and cell biology 150 (1), 77-82, 2018 | 7 | 2018 |
Detection of Bax microsatellite mutations and BaxΔ2 isoform in human buccal cells H Zhang, C Tassone, N Lin, A Mañas, Y Zhao, J Xiang Journal of cell science & therapy 6 (Suppl 8), 2015 | 7 | 2015 |
Macrophage infiltration promotes regrowth in MYCN-amplified neuroblastoma after chemotherapy A Valind, BM Verhoeven, J Enoksson, J Karlsson, G Christensson, ... Oncoimmunology 12 (1), 2184130, 2023 | 5 | 2023 |
Ubl4A is critical for mitochondrial fusion process under nutrient deprivation stress H Zhang, Y Zhao, Q Yao, Z Ye, A Mañas, J Xiang Plos one 15 (11), e0242700, 2020 | 4 | 2020 |
Expression profile of the proapoptotic protein Bax in the human brain Q Yao, H Zhang, C Standish, J Grube, A Mañas, J Xiang Histochemistry and Cell Biology 159 (2), 209-220, 2023 | 2 | 2023 |
Inherent evolutionary unpredictability in cancer model system S Chattopadhyay, J Karlsson, A Mañas, R Kanzaki, E Fredlund, ... bioRxiv, 2022.06. 01.494285, 2022 | 1 | 2022 |
BaxΔ2: From Functional Domains to Cancer Correlation A Manas Nunez Illinois Institute of Technology, 2018 | 1 | 2018 |
Unconventional Source of Neurotoxic Protein Aggregation from Organelle Off-Target Bax∆ 2 in Alzheimer’s Disease Q Yao, AC Mascarenhas dos Santos, H Zhang, A Mañas, A Hussaini, ... Biomolecules 13 (6), 970, 2023 | | 2023 |
Early evolutionary branching across spatial domains predisposes to clonal replacement under chemotherapy in neuroblastoma D Gisselsson, J Karlsson, H Yasui, A Manas, N Andersson, K Hansson, ... | | 2022 |
Modeling and deciphering COJEC resistance in high risk neuroblastoma A Manas, K Aaltonen, N Andersson, K Hansson, A Seger, H Yasui, ... Cancer Research 82 (12_Supplement), 3901-3901, 2022 | | 2022 |