| The BET bromodomain inhibitor CPI203 overcomes resistance to ABT-199 (venetoclax) by downregulation of BFL-1/A1 in in vitro and in vivo models of MYC+/BCL2+ double hit lymphoma A Esteve-Arenys, JG Valero, A Chamorro-Jorganes, D Gonzalez, ... Oncogene 37 (14), 1830-1844, 2018 | 87 | 2018 |
| Bax-derived membrane-active peptides act as potent and direct inducers of apoptosis in cancer cells JG Valero, L Sancey, J Kucharczak, Y Guillemin, D Gimenez, J Prudent, ... Journal of cell science 124 (4), 556-564, 2011 | 67 | 2011 |
| Mutations in the RAS-BRAF-MAPK-ERK pathway define a specific subgroup of patients with adverse clinical features and provide new therapeutic options in chronic lymphocytic leukemia N Giménez, A Martínez-Trillos, A Montraveta, M Lopez-Guerra, L Rosich, ... Haematologica 104 (3), 576, 2019 | 53 | 2019 |
| Daratumumab displays in vitro and in vivo anti-tumor activity in models of B cell non-Hodgkin lymphoma and improves responses to standard chemo-immunotherapy regimens. A Vidal-Crespo, A Matas-Céspedes, V Rodriguez, C Rossi, JG Valero, ... Haematologica 104 (7), 2019 | 41 | 2019 |
| The receptor of the colony-stimulating factor-1 (CSF-1R) is a novel prognostic factor and therapeutic target in follicular lymphoma JG Valero, A Matas-Céspedes, F Arenas, V Rodriguez, J Carreras, ... Leukemia, 2021 | 40 | 2021 |
| Active fragments from pro-and antiapoptotic BCL-2 proteins have distinct membrane behavior reflecting their functional divergence Y Guillemin, J Lopez, D Gimenez, G Fuertes, JG Valero, L Blum, ... PloS one 5 (2), e9066, 2010 | 31 | 2010 |
| µ-Calpain conversion of antiapoptotic Bfl-1 (BCL2A1) into a prodeath factor reveals two distinct alpha-helices inducing mitochondria-mediated apoptosis JG Valero, A Cornut-Thibaut, R Juge, AL Debaud, D Gimenez, G Gillet, ... PloS one 7 (6), e38620, 2012 | 28 | 2012 |
| PI3Kδ inhibition reshapes follicular lymphoma–immune microenvironment cross talk and unleashes the activity of venetoclax N Serrat, M Guerrero-Hernández, A Matas-Céspedes, A Yahiaoui, ... Blood advances 4 (17), 4217-4231, 2020 | 27 | 2020 |
| Apaf-1 Inhibitors Protect from Unwanted Cell Death in In Vivo Models of Kidney Ischemia and Chemotherapy Induced Ototoxicity M Orzaez, M Sancho, S Marchan, L Mondragon, R Montava, JG Valero, ... PloS one 9 (10), e110979, 2014 | 27 | 2014 |
| Activity of the novel BCR kinase inhibitor IQS019 in preclinical models of B-cell non-Hodgkin lymphoma P Balsas, A Esteve-Arenys, J Roldán, L Jiménez, V Rodríguez, JG Valero, ... Journal of Hematology & Oncology 10, 1-14, 2017 | 17 | 2017 |
| 3D Model Characterization by 2D and 3D Imaging in t (14; 18)-Positive B-NHL: Perspectives for In Vitro Drug Screens in Follicular Lymphoma F Gava, C Faria, P Gravelle, JG Valero, C Dobaño-López, R Morin, ... Cancers 13 (7), 1490, 2021 | 13 | 2021 |
| Lipid-dependent bimodal MCL1 membrane activity O Landeta, JG Valero, H Flores-Romero, I Bustillo-Zabalbeitia, ... ACS chemical biology 9 (12), 2852-2863, 2014 | 13 | 2014 |
| Follicular Lymphoma Microenvironment: An Intricate Network Ready for Therapeutic Intervention C Dobaño-López, F Araujo-Ayala, N Serrat, JG Valero, P Pérez-Galán Cancers 13 (4), 641, 2021 | 11 | 2021 |
| Lipidomic profile of GM95 cell death induced by Clostridium perfringens alpha-toxin MM Manni, JG Valero, M Pérez-Cormenzana, A Cano, C Alonso, FM Goñi Chemistry and physics of lipids 203, 54-70, 2017 | 11 | 2017 |
| A novel patient-derived 3D model recapitulates mantle cell lymphoma lymph node signaling, immune profile and in vivo ibrutinib responses F Araujo-Ayala, C Dobaño-López, JG Valero, F Nadeu, F Gava, C Faria, ... Leukemia 37 (6), 1311-1323, 2023 | 7 | 2023 |
| Revised International Prognostic Index and genetic alterations are associated with early failure to R‐CHOP in patients with diffuse large B‐cell lymphoma I Dlouhy, K Karube, A Enjuanes, I Salaverria, F Nadeu, JE Ramis‐Zaldivar, ... British Journal of Haematology 196 (3), 589-598, 2022 | 4 | 2022 |
| Cardiac fibroblasts display endurance to ischemia, high ROS control and elevated respiration regulated by the JAK2/STAT pathway A Beà, J García Valero, A Irazoki, C Lana, G López‐Lluch, M Portero‐Otín, ... The FEBS Journal, 2021 | 3 | 2021 |
| DECIPHERING THE CONTRIBUTION OF MACROPHAGES TO FOLLICULAR LYMPHOMA PATHOGENESIS: NEW INSIGHTS INTO THERAPY P Perez Galan, JG Valero, A Matas‐Cespedes, V Rodriguez, F Arenas, ... Hematological Oncology 37, 151-152, 2019 | 2 | 2019 |
| Idelalisib interferes with the crosstalk of follicular lymphoma and its immune microenvironment and potentiates the activity of ABT-199 M Guerrero-Hernandez, A Matas-Cespedes, N Serrat, A Yahiaoui, ... Blood 130, 2813, 2017 | 2 | 2017 |
| Pharmacological downregulation of BFL-1 by the BET bromodomain inhibitor CPI203 overcomes ABT-199 resistance in MYC+/BCL2+ double hit lymphoma A Esteve-Arenys, J Garcia-Valero, D Gonzalez, A Chamorro-Jorganes, ... Cancer Research 77 (13_Supplement), 2161-2161, 2017 | 2 | 2017 |
Gaël RouéGroup leader, Josep Carreras Leukaemia Research InsituteVerified email at carrerasresearch.org
