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Paul-Alain Jaffrès
Paul-Alain Jaffrès
Professor of Chemistry
Verified email at univ-brest.fr - Homepage
Title
Cited by
Cited by
Year
Chemical vectors for gene delivery: a current review on polymers, peptides and lipids containing histidine or imidazole as nucleic acids carriers
P Midoux, C Pichon, JJ Yaouanc, PA Jaffrès
British journal of pharmacology 157 (2), 166-178, 2009
6612009
Enhancement of dendritic cells transfection in vivo and of vaccination against B16F10 melanoma with mannosylated histidylated lipopolyplexes loaded with tumor antigen messenger RNA
F Perche, T Benvegnu, M Berchel, L Lebegue, C Pichon, PA Jaffrès, ...
Nanomedicine: Nanotechnology, Biology and Medicine 7 (4), 445-453, 2011
2912011
Progress in cationic lipid-mediated gene transfection: a series of bio-inspired lipids as an example
T Montier, T Benvegnu, PA Jaffrès, JJ Yaouanc, P Lehn
Current gene therapy 8 (5), 296-312, 2008
1922008
Pivotal role of the lipid Raft SK3–Orai1 complex in human cancer cell migration and bone metastases
A Chantôme, M Potier-Cartereau, L Clarysse, G Fromont, ...
Cancer research 73 (15), 4852-4861, 2013
1912013
Atherton–Todd reaction: mechanism, scope and applications
SS Le Corre, M Berchel, H Couthon-Gourvès, JP Haelters, PA Jaffrès
Beilstein journal of organic chemistry 10 (1), 1166-1196, 2014
1902014
A silver-based metal–organic framework material as a ‘reservoir’of bactericidal metal ions
M Berchel, T Le Gall, C Denis, S Le Hir, F Quentel, C Elléouet, T Montier, ...
New Journal of Chemistry 35 (5), 1000-1003, 2011
1762011
Phosphonic acid: preparation and applications
CM Sevrain, M Berchel, H Couthon, PA Jaffrès
Beilstein journal of organic chemistry 13 (1), 2186-2213, 2017
1632017
SK3/TRPC1/Orai1 complex regulates SOCE-dependent colon cancer cell migration: a novel opportunity to modulate anti-EGFR mAb action by the alkyl-lipid Ohmline
M Guéguinou, T Harnois, D Crottes, A Uguen, N Deliot, A Gambade, ...
Oncotarget 7 (24), 36168, 2016
1192016
DODAG; a versatile new cationic lipid that mediates efficient delivery of pDNA and siRNA
M Mével, N Kamaly, S Carmona, MH Oliver, MR Jorgensen, C Crowther, ...
Journal of Controlled Release 143 (2), 222-232, 2010
1132010
Dendritic Cell Targeting mRNA Lipopolyplexes Combine Strong Antitumor T-Cell Immunity with Improved Inflammatory Safety
K Van der Jeught, S De Koker, L Bialkowski, C Heirman, P Tjok Joe, ...
ACS nano 12 (10), 9815-9829, 2018
1122018
Gene transfer by chemical vectors, and endocytosis routes of polyplexes, lipoplexes and lipopolyplexes in a myoblast cell line
L Billiet, JP Gomez, M Berchel, PA Jaffrès, T Le Gall, T Montier, E Bertrand, ...
Biomaterials 33 (10), 2980-2990, 2012
1102012
Preclinical evaluation of mRNA trimannosylated lipopolyplexes as therapeutic cancer vaccines targeting dendritic cells
A Le Moignic, V Malard, T Benvegnu, L Lemiègre, M Berchel, PA Jaffrès, ...
Journal of Controlled Release 278, 110-121, 2018
1002018
Synthesis of highly functionalised dendrimers based on polyhedral silsesquioxane cores
PA Jaffres, RE Morris
Journal of the Chemical Society, Dalton Transactions, 2767-2770, 1998
981998
Synthesis and transfection activity of new cationic phosphoramidate lipids: high efficiency of an imidazolium derivative
M Mével, G Breuzard, JJ Yaouanc, JC Clément, P Lehn, C Pichon, ...
ChemBioChem 9 (9), 1462-1471, 2008
962008
A novel cationic lipophosphoramide with diunsaturated lipid chains: synthesis, physicochemical properties, and transfection activities
T Le Gall, D Loizeau, E Picquet, N Carmoy, JJ Yaouanc, ...
Journal of medicinal chemistry 53 (4), 1496-1508, 2010
952010
Design of sulfides with a locked conformation as promoters of catalytic and asymmetric sulfonium ylide epoxidation
M Davoust, JF Brière, PA Jaffrès, P Metzner
The Journal of organic chemistry 70 (10), 4166-4169, 2005
882005
Targeting SKCa channels in cancer: potential new therapeutic approaches
A Girault, JP Haelters, M Potier-Cartereau, A Chantôme, PA Jaffres, ...
Current medicinal chemistry 19 (5), 697-713, 2012
802012
Selective gene delivery in dendritic cells with mannosylated and histidylated lipopolyplexes
F Perche, D Gosset, M Mével, ML Miramon, JJ Yaouanc, C Pichon, ...
Journal of drug targeting 19 (5), 315-325, 2011
772011
Alkyl ether lipids, ion channels and lipid raft reorganization in cancer therapy
PA Jaffres, C Gajate, AM Bouchet, H Couthon-Gourves, A Chantôme, ...
Pharmacology & therapeutics 165, 114-131, 2016
712016
New alkyl-lipid blockers of SK3 channels reduce cancer cell migration and occurrence of metastasis
A Girault, JP Haelters, M Potier-Cartereau, A Chantôme, M Pinault, ...
Current cancer drug targets 11 (9), 1111-1125, 2011
702011
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