| US FDA approved drugs from 2015–June 2020: a perspective P Bhutani, G Joshi, N Raja, N Bachhav, PK Rajanna, H Bhutani, AT Paul, ... Journal of Medicinal Chemistry 64 (5), 2339-2381, 2021 | 379 | 2021 |
| Design, synthesis, and pharmacokinetic evaluation of phosphate and amino acid ester prodrugs for improving the oral bioavailability of the HIV-1 protease inhibitor atazanavir M AM Subbaiah, S Mandlekar, S Desikan, T Ramar, L Subramani, ... Journal of Medicinal Chemistry 62 (7), 3553-3574, 2019 | 26 | 2019 |
| Absorption and cleavage of enalapril, a carboxyl ester prodrug, in the rat intestine: in vitro, in situ intestinal perfusion and portal vein cannulation models VK Holenarsipur, N Gaud, J Sinha, S Sivaprasad, P Bhutani, ... Biopharmaceutics & drug disposition 36 (6), 385-397, 2015 | 24 | 2015 |
| Coupling of an acyl migration prodrug strategy with bio-activation to improve oral delivery of the HIV-1 protease inhibitor atazanavir MAM Subbaiah, NA Meanwell, JF Kadow, L Subramani, M Annadurai, ... Journal of Medicinal Chemistry 61 (9), 4176-4188, 2018 | 12 | 2018 |
| Role of hepatic blood flow and metabolism in the pharmacokinetics of ten drugs in lean, aged and obese rats M Subramanian, V Kurawattimath, K Pocha, C Freeden, I Rao, ... Xenobiotica 44 (12), 1108-1116, 2014 | 12 | 2014 |
| Targeting the epidermal growth factor receptor with molecular degraders: State-of-the-art and future opportunities P Maity, J Chatterjee, KT Patil, S Arora, MK Katiyar, M Kumar, ... Journal of Medicinal Chemistry 66 (5), 3135-3172, 2023 | 9 | 2023 |
| (Carbonyl) oxyalkyl linker-based amino acid prodrugs of the HIV-1 protease inhibitor atazanavir that enhance oral bioavailability and plasma trough concentration MAM Subbaiah, T Ramar, L Subramani, SD Desai, S Sinha, S Mandlekar, ... European Journal of Medicinal Chemistry 207, 112749, 2020 | 6 | 2020 |
| Comprehensive evaluation of liver microsomal cytochrome P450 3A (CYP3A) inhibition: comparison of cynomolgus monkey and human ZE Haarhoff, MA Kramer, TA Zvyaga, J Zhang, P Bhutani, M Subramanian, ... Xenobiotica 47 (6), 470-478, 2017 | 6 | 2017 |
| Expression and Characterization of Cynomolgus Monkey Cytochrome CYP3A4 in a Novel Human Embryonic Kidney Cell–Based Mammalian System S Selvakumar, P Bhutani, K Ghosh, P Krishnamurthy, S Kallipatti, ... Drug Metabolism and Disposition 42 (3), 369-376, 2014 | 6 | 2014 |
| Rapid and cost‐effective LC–MS/MS method for determination of hydroxycitric acid in plasma: Application in the determination of pharmacokinetics in commercial Garcinia preparations P Bhutani, R U, S HN, PK Ranjanna, AT Paul Biomedical Chromatography 34 (10), e4902, 2020 | 5 | 2020 |
| Unanticipated Cleavage of 2-Nitrophenyl-Substituted N-Formyl Pyrazolines under Bechamp Conditions: Unveiling the Synthesis of 2-Aryl Quinolines and Their … G Joshi, AA Wani, S Sharma, P Bhutani, PV Bharatam, AT Paul, R Kumar ACS omega 3 (12), 18783-18790, 2018 | 5 | 2018 |
| Offline derivatization LC–MS/MS method for simultaneous estimation of vanillin and vanillic acid in guinea pig plasma P Bhutani, S Murugesan, A Kumar, M Subramanian, KR Prabhakar Bioanalysis 10 (3), 131-142, 2018 | 4 | 2018 |
| Inhibition of Toll-Like Receptor 7 (TLR7) with the Potent and Selective Inhibitor of Human TLR7 and TLR8 BMS-986256 Provides Robust Efficacy in Murine Lupus Models, Reversing … S Dudhgaonkar, A Rudra, S Ranade, S Subramani, J Nagar, ... ARTHRITIS & RHEUMATOLOGY 73, 973-974, 2021 | 2 | 2021 |
| Impact of quercetin on pharmacokinetics of quetiapine: insights from in-vivo studies in wistar rats P Bhutani, PK Rajanna, AT Paul Xenobiotica 50 (12), 1483-1489, 2020 | 2 | 2020 |
| Absolute quantification of imipramine and its metabolites in vivo utilizing calibrators from radiolabeled in vitro incubations P Bhutani, D Shah, N Varkhede, S Mandlekar, S Chacko, M Subramanian Bioanalysis 8 (4), 297-309, 2016 | 2 | 2016 |
| Improving Drug Delivery While Tailoring Prodrug Activation to Modulate Cmax and Cmin by Optimization of (Carbonyl)oxyalkyl Linker-Based Prodrugs of … M AM Subbaiah, L Subramani, T Ramar, S Desai, S Sinha, S Mandlekar, ... Journal of Medicinal Chemistry 65 (16), 11150-11176, 2022 | 1 | 2022 |
| Qualified method for the estimation of di-18: 1 bis (monoacylglycero) phosphate in urine, a noninvasive biomarker to monitor drug-induced phospholipidosis BV Murali, V Kurawattimath, P Bhutani, J Onorato, SB Naikodi, P Kole, ... Bioanalysis 12 (15), 1049-1059, 2020 | 1 | 2020 |
| Identification of novel glutathione conjugates of terbinafine in liver microsomes and hepatocytes across species A Patil, MK Ladumor, SH Kamble, BM Johnson, M Subramanian, MW Sinz, ... Xenobiotica, 2019 | 1 | 2019 |
| PO. 1.1 Afimetoran, a potent and selective inhibitor of human toll-like receptor 7 (TLR7) and tlr8, provides robust efficacy in a murine lupus model of advanced disease S Dudhgaonkar, A Rudra, S Ranade, S Subramani, J Nagar, ... Lupus Science & Medicine 9 (Suppl 2), 2022 | | 2022 |
| EXPRESSION AND CHARACTERIZATION OF CYNOMOLGUS CYTOCHROME P450 3A4 M Subramanian, P Bhutani, S Selvakumar, S Mandlekar, K Ghosh DRUG METABOLISM REVIEWS 45, 89-89, 2014 | | 2014 |
