Mitochondrial and cytoplasmic ROS have opposing effects on lifespan CE Schaar, DJ Dues, KK Spielbauer, E Machiela, JF Cooper, M Senchuk, ... PLOS Genetics 11 (2), e1004972, 2015 | 207 | 2015 |
Activation of DAF-16/FOXO by reactive oxygen species contributes to longevity in long-lived mitochondrial mutants in Caenorhabditis elegans MM Senchuk, DJ Dues, CE Schaar, BK Johnson, ZB Madaj, MJ Bowman, ... PLOS Genetics 14 (3), e1007268, 2018 | 129 | 2018 |
Aging causes decreased resistance to multiple stresses and a failure to activate specific stress response pathways DJ Dues, EK Andrews, CE Schaar, AL Bergsma, MM Senchuk, ... Aging 8 (4), 777-795, 2016 | 109 | 2016 |
Activation of the mitochondrial unfolded protein response promotes longevity and dopamine neuron survival in Parkinson's disease models JF Cooper, E Machiela, DJ Dues, KK Spielbauer, MM Senchuk, ... Scientific Reports 7 (1), 16441, 2017 | 91 | 2017 |
Mitochondrial unfolded protein response transcription factor ATFS-1 promotes longevity in a long-lived mitochondrial mutant through activation of stress response pathways Z Wu, MM Senchuk, DJ Dues, BK Johnson, JF Cooper, L Lew, E Machiela, ... BMC biology 16, 1-19, 2018 | 89 | 2018 |
Delaying aging is neuroprotective in Parkinson’s disease: a genetic analysis in C. elegans models JF Cooper, DJ Dues, KK Spielbauer, E Machiela, MM Senchuk, ... Nature Partner Journal Parkinson's Disease 1, 15022, 2015 | 83 | 2015 |
Uncoupling of oxidative stress resistance and lifespan in long-lived isp-1 mitochondrial mutants in Caenorhabditis elegans DJ Dues, CE Schaar, BK Johnson, MJ Bowman, ME Winn, MM Senchuk, ... Free Radical Biology and Medicine 108, 362-373, 2017 | 78 | 2017 |
Measuring oxidative stress in Caenorhabditis elegans: paraquat and juglone sensitivity assays MM Senchuk, DJ Dues, JM Van Raamsdonk Bio-Protocol 7 (1), e2086, 2017 | 74* | 2017 |
Resistance to stress can be experimentally dissociated from longevity DJ Dues, EK Andrews, MM Senchuk, JM Van Raamsdonk The Journals of Gerontology: Series A 74 (8), 1206-1214, 2019 | 46 | 2019 |
Oxidative stress is increased in C. elegans models of Huntington’s disease but does not contribute to polyglutamine toxicity phenotypes E Machiela, DJ Dues, MM Senchuk, JM Van Raamsdonk Neurobiology of Disease 96, 1-11, 2016 | 43 | 2016 |
Intrastriatal transplantation of adenovirus-generated induced pluripotent stem cells for treating neuropathological and functional deficits in a rodent model of Huntington’s … KD Fink, AT Crane, X Lévêque, DJ Dues, LD Huffman, AC Moore, ... Stem Cells Translational Medicine 3 (5), 620-631, 2014 | 41 | 2014 |
Survival and differentiation of adenovirus-generated induced pluripotent stem cells transplanted into the rat striatum KD Fink, J Rossignol, M Lu, X Lévêque, TD Hulse, AT Crane, ... Cell Transplantation 23 (11), 1407-1423, 2014 | 32 | 2014 |
Disruption of mitochondrial dynamics increases stress resistance through activation of multiple stress response pathways E Machiela, T Liontis, DJ Dues, PD Rudich, A Traa, L Wyman, C Kaufman, ... The FASEB Journal, 2020 | 27 | 2020 |
Neuronal VPS35 deletion induces spinal cord motor neuron degeneration and early post-natal lethality D Sargent, LA Cunningham, DJ Dues, Y Ma, JJ Kordich, G Mercado, ... Brain Communications 3 (3), fcab208, 2021 | 14 | 2021 |
LRRK2 and protein aggregation in Parkinson’s disease: insights from animal models DJ Dues, DJ Moore Frontiers in Neuroscience 14, 558161, 2020 | 13 | 2020 |
Formation of templated inclusions in a forebrain α-synuclein mouse model is independent of LRRK2 DJ Dues, Y Ma, APT Nguyen, AV Offerman, I Beddows, DJ Moore Neurobiology of disease 188, 106338, 2023 | 2 | 2023 |
Hippocampal subfield vulnerability to α-synuclein pathology precedes neurodegeneration and cognitive dysfunction DJ Dues, APT Nguyen, K Becker, J Ma, DJ Moore npj Parkinson's Disease 9 (1), 125, 2023 | 2 | 2023 |
Measuring sensitivity to oxidative stress: the superoxide-generator juglone rapidly loses potency with time JF Cooper, DJ Dues, JM Van Raamsdonk Worm Breeder's Gazette, 2016 | 2 | 2016 |
Investigating mouse models of Lewy-related pathology and cognitive dysfunction DJ Dues Dissertation, Van Andel Institute, 2023 | | 2023 |