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Bruce Sachais
Bruce Sachais
Chief Medical Officer, New York Blood Center
Verified email at nybc.org
Title
Cited by
Cited by
Year
Deployment of convalescent plasma for the prevention and treatment of COVID-19
EM Bloch, S Shoham, A Casadevall, BS Sachais, B Shaz, JL Winters, ...
The Journal of clinical investigation 130 (6), 2757-2765, 2020
9382020
Evidence‐based practice guidelines for plasma transfusion
JD Roback, S Caldwell, J Carson, R Davenport, MJ Drew, A Eder, M Fung, ...
Transfusion 50 (6), 1227-1239, 2010
3682010
Ultralarge complexes of PF4 and heparin are central to the pathogenesis of heparin-induced thrombocytopenia
L Rauova, M Poncz, SE McKenzie, MP Reilly, G Arepally, JW Weisel, ...
Blood 105 (1), 131-138, 2005
3202005
Heparin-induced thrombocytopenia/thrombosis in a transgenic mouse model requires human platelet factor 4 and platelet activation through FcγRIIA
MP Reilly, SM Taylor, NK Hartman, GM Arepally, BS Sachais, DB Cines, ...
Blood, The Journal of the American Society of Hematology 98 (8), 2442-2447, 2001
2812001
Convalescent plasma for hospitalized patients with COVID-19: an open-label, randomized controlled trial
P Bégin, J Callum, E Jamula, R Cook, NM Heddle, A Tinmouth, MP Zeller, ...
Nature medicine 27 (11), 2012-2024, 2021
2402021
Platelet factor 4 localization in carotid atherosclerotic plaques: correlation with clinical parameters
S Pitsilos, J Hunt, ER Mohler, AM Prabhakar, M Poncz, J Dawicki, ...
Thrombosis and haemostasis 90 (12), 1112-1120, 2003
2322003
Efficacy of transfusion with granulocytes from G-CSF/dexamethasone–treated donors in neutropenic patients with infection
TH Price, M Boeckh, RW Harrison, J McCullough, PM Ness, RG Strauss, ...
Blood, The Journal of the American Society of Hematology 126 (18), 2153-2161, 2015
2242015
Molecular cloning, structural characterization and functional expression of the human substance P receptor
Y Takeda, KB Chou, J Takeda, BS Sachais, JE Krause
Biochemical and biophysical research communications 179 (3), 1232-1240, 1991
2191991
Factor VIII ectopically expressed in platelets: efficacy in hemophilia A treatment
HV Yarovoi, D Kufrin, DE Eslin, MA Thornton, SL Haberichter, Q Shi, ...
Blood 102 (12), 4006-4013, 2003
2142003
Platelet factor 4 enhances the binding of oxidized low-density lipoprotein to vascular wall cells
T Nassar, BS Sachais, S Akkawi, MA Kowalska, K Bdeir, E Leitersdorf, ...
Journal of Biological Chemistry 278 (8), 6187-6193, 2003
1962003
Elimination of platelet factor 4 (PF4) from platelets reduces atherosclerosis in C57Bl/6 and apoE-/-mice
BS Sachais, T Turrentine, JMD McKenna, AH Rux, D Rader, ...
Thrombosis and haemostasis 98 (11), 1108-1113, 2007
1782007
A peptide derived from the nonreceptor binding region of urokinase plasminogen activator (uPA) inhibits tumor progression and angiogenesis and induces tumor cell death in vivo
Y Guo, AAR Higazi, A Arakelian, BS Sachais, D Cines, RH Goldfarb, ...
The FASEB Journal 14 (10), 1400-1410, 2000
1572000
Endothelial expression of E-selectin is induced by the platelet-specific chemokine platelet factor 4 through LRP in an NF-κB–dependent manner
G Yu, AH Rux, P Ma, K Bdeir, BS Sachais
Blood 105 (9), 3545-3551, 2005
1542005
Molecular basis for the species selectivity of the substance P antagonist CP-96,345.
BS Sachais, RM Snider, JA Lowe 3rd, JE Krause
Journal of Biological Chemistry 268 (4), 2319-2323, 1993
1521993
The cooperative activity between the carboxyl-terminal TSP1 repeats and the CUB domains of ADAMTS13 is crucial for recognition of von Willebrand factor under flow
P Zhang, W Pan, AH Rux, BS Sachais, XL Zheng
Blood, The Journal of the American Society of Hematology 110 (6), 1887-1894, 2007
1482007
Platelets regulate CD4+ T-cell differentiation via multiple chemokines in humans
N Gerdes, L Zhu, M Ersoy, A Hermansson, P Hjemdahl, H Hu, ...
Thrombosis and haemostasis 106 (08), 353-362, 2011
1422011
Platelet factor 4 binds to low-density lipoprotein receptors and disrupts the endocytic itinerary, resulting in retention of low-density lipoprotein on the cell surface
BS Sachais, A Kuo, T Nassar, J Morgan, K Kariko, KJ Williams, ...
Blood, The Journal of the American Society of Hematology 99 (10), 3613-3622, 2002
1272002
Ligand binding kinetics of substance P and neurokinin A receptors stably expressed in Chinese hamster ovary cells and evidence for differential stimulation of inositol 1, 4, 5 …
Y Takeda, P Blount, BS Sachais, AD Hershey, R Raddatz, JE Krause
Journal of neurochemistry 59 (2), 740-745, 1992
1181992
Heparin‐induced thrombocytopenia: an autoimmune disorder regulated through dynamic autoantigen assembly/disassembly
DB Cines, L Rauova, G Arepally, MP Reilly, SE McKenzie, BS Sachais, ...
Journal of Clinical Apheresis: The Official Journal of the American Society …, 2007
1012007
Defensin promotes the binding of lipoprotein (a) to vascular matrix
K Bdeir, W Cane, G Canziani, I Chaiken, J Weisel, ML Koschinsky, ...
Blood, The Journal of the American Society of Hematology 94 (6), 2007-2019, 1999
951999
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