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Javier Robles Valero ORCID 0000-0001-5218-0187
Javier Robles Valero ORCID 0000-0001-5218-0187
Investigador Postdoctoral, Centro de Investigación del Cáncer; Profesor Asociado USAL
Verified email at usal.es
Title
Cited by
Cited by
Year
MTOC translocation modulates IS formation and controls sustained T cell signaling
NB Martin-Cofreces, J Robles-Valero, JR Cabrero, M Mittelbrunn, ...
The Journal of cell biology 182 (5), 951-962, 2008
2082008
Miro-1 links mitochondria and microtubule Dynein motors to control lymphocyte migration and polarity
G Morlino, O Barreiro, F Baixauli, J Robles-Valero, JM González-Granado, ...
Molecular and cellular biology 34 (8), 1412-1426, 2014
1352014
Activating mutations and translocations in the guanine exchange factor VAV1 in peripheral T-cell lymphomas
F Abate, AC da Silva-Almeida, S Zairis, J Robles-Valero, L Couronne, ...
Proceedings of the National Academy of Sciences 114 (4), 764-769, 2017
1192017
Endosomal clathrin drives actin accumulation at the immunological synapse
C Calabia-Linares, J Robles-Valero, H de la Fuente, M Perez-Martinez, ...
Journal of cell science 124 (5), 820-830, 2011
982011
A paradoxical tumor-suppressor role for the Rac1 exchange factor Vav1 in T cell acute lymphoblastic leukemia
J Robles-Valero, LF Lorenzo-Martín, M Menacho-Marquez, ...
Cancer Cell 32 (5), 608-623. e9, 2017
422017
Integrin and CD3/TCR activation are regulated by the scaffold protein AKAP450
J Robles-Valero, NB Martín-Cófreces, A Lamana, S Macdonald, Y Volkov, ...
Blood, The Journal of the American Society of Hematology 115 (21), 4174-4184, 2010
352010
VAV2 signaling promotes regenerative proliferation in both cutaneous and head and neck squamous cell carcinoma
LF Lorenzo-Martín, N Fernández-Parejo, M Menacho-Márquez, ...
Nature Communications 11 (1), 4788, 2020
342020
Immunosuppression-independent role of regulatory T cells against hypertension-driven renal dysfunctions
S Fabbiano, M Menacho-Márquez, J Robles-Valero, M Pericacho, ...
Molecular and Cellular Biology 35 (20), 3528-3546, 2015
332015
Vav proteins maintain epithelial traits in breast cancer cells using miR-200c-dependent and independent mechanisms
LF Lorenzo-Martín, C Citterio, M Menacho-Márquez, J Conde, RM Larive, ...
Oncogene 38 (2), 209-227, 2019
182019
Cancer‐associated mutations in VAV1 trigger variegated signaling outputs and T‐cell lymphomagenesis
J Robles‐Valero, L Fernández‐Nevado, LF Lorenzo‐Martín, M Cuadrado, ...
The EMBO journal 40 (22), e108125, 2021
132021
Rho guanosine nucleotide exchange factors are not such bad guys after all in cancera
J Robles-Valero, LF Lorenzo-Martín, I Fernández-Pisonero, XR Bustelo
Small GTPases 11 (4), 233-239, 2020
112020
A hotspot mutation targeting the R-RAS2 GTPase acts as a potent oncogenic driver in a wide spectrum of tumors
I Fernandez-Pisonero, L Clavaín, J Robles-Valero, LF Lorenzo-Martín, ...
Cell Reports 38 (11), 2022
102022
Vav2 pharmaco-mimetic mice reveal the therapeutic value and caveats of the catalytic inactivation of a Rho exchange factor
LF Lorenzo-Martín, S Rodriguez-Fdez, S Fabbiano, A Abad, ...
Oncogene 39 (28), 5098-5111, 2020
102020
Computational and in vitro Pharmacodynamics Characterization of 1A-116 Rac1 Inhibitor: Relevance of Trp56 in Its Biological Activity
N González, GA Cardama, P Chinestrad, J Robles-Valero, ...
Frontiers in Cell and Developmental Biology 8, 240, 2020
102020
Clathrin regulates lymphocyte migration by driving actin accumulation at the cellular leading edge
G Ramírez‐Santiago, J Robles‐Valero, G Morlino, A Cruz‐Adalia, ...
European journal of immunology 46 (10), 2376-2387, 2016
92016
VAV proteins as double agents in cancer: oncogenes with tumor suppressor roles
M Cuadrado, J Robles-Valero
Biology 10 (9), 888, 2021
72021
The disease-linked Glu-26-Lys mutant version of Coronin 1A exhibits pleiotropic and pathway-specific signaling defects
V Ojeda, J Robles-Valero, M Barreira, XR Bustelo
Molecular biology of the cell 26 (16), 2895-2912, 2015
72015
Characterization of the spectrum of trivalent VAV1‐mutation‐driven tumours using a gene‐edited mouse model
J Robles‐Valero, L Fernández‐Nevado, M Cuadrado, LF Lorenzo‐Martín, ...
Molecular Oncology 16 (19), 3533-3553, 2022
32022
An unexpected tumor suppressor role for VAV1a
XR Bustelo, LF Lorenzo-Martín, M Cuadrado, I Fernández-Pisonero, ...
Molecular & Cellular Oncology 5 (3), e1432257, 2018
22018
Distinct roles of vav family members in adaptive and innate immune models of arthritis
J Conde, I Fernández-Pisonero, M Cuadrado, A Abad, J Robles-Valero, ...
Biomedicines 9 (6), 695, 2021
12021
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