| Protein aggregation: pathways, induction factors and analysis HC Mahler, W Friess, U Grauschopf, S Kiese Journal of pharmaceutical sciences 98 (9), 2909-2934, 2009 | 992 | 2009 |
| Shaken, not stirred: mechanical stress testing of an IgG1 antibody S Kiese, A Papppenberger, W Friess, HC Mahler Journal of pharmaceutical sciences 97 (10), 4347-4366, 2008 | 452 | 2008 |
| An industry perspective on the monitoring of subvisible particles as a quality attribute for protein therapeutics SK Singh, N Afonina, M Awwad, K Bechtold-Peters, JT Blue, D Chou, ... Journal of pharmaceutical sciences 99 (8), 3302-3321, 2010 | 347 | 2010 |
| Induction and analysis of aggregates in a liquid IgG1-antibody formulation HC Mahler, R Müller, W Frieβ, A Delille, S Matheus European journal of pharmaceutics and biopharmaceutics 59 (3), 407-417, 2005 | 342 | 2005 |
| Degradation of polysorbates 20 and 80: studies on thermal autoxidation and hydrolysis RSK Kishore, A Pappenberger, IB Dauphin, A Ross, B Buergi, A Staempfli, ... Journal of pharmaceutical sciences 100 (2), 721-731, 2011 | 289 | 2011 |
| The degradation of polysorbates 20 and 80 and its potential impact on the stability of biotherapeutics RSK Kishore, S Kiese, S Fischer, A Pappenberger, U Grauschopf, ... Pharmaceutical research 28, 1194-1210, 2011 | 277 | 2011 |
| Forced degradation of therapeutic proteins A Hawe, M Wiggenhorn, M van de Weert, JHO Garbe, H Mahler, ... Journal of pharmaceutical sciences 101 (3), 895-913, 2012 | 269 | 2012 |
| Key interactions of surfactants in therapeutic protein formulations: a review TA Khan, HC Mahler, RSK Kishore European journal of pharmaceutics and biopharmaceutics 97, 60-67, 2015 | 238 | 2015 |
| Assessment of net charge and protein–protein interactions of different monoclonal antibodies C Lehermayr, HC Mahler, K Mäder, S Fischer Journal of pharmaceutical sciences 100 (7), 2551-2562, 2011 | 213 | 2011 |
| FTIR and nDSC as analytical tools for high-concentration protein formulations S Matheus, W Friess, HC Mahler Pharmaceutical research 23, 1350-1363, 2006 | 148 | 2006 |
| Freeze drying of human serum albumin (HSA) nanoparticles with different excipients MG Anhorn, HC Mahler, K Langer International journal of pharmaceutics 363 (1-2), 162-169, 2008 | 143 | 2008 |
| Subcutaneous injection volume of biopharmaceuticals—pushing the boundaries R Mathaes, A Koulov, S Joerg, HC Mahler Journal of pharmaceutical sciences 105 (8), 2255-2259, 2016 | 130 | 2016 |
| Glycation during storage and administration of monoclonal antibody formulations S Fischer, J Hoernschemeyer, HC Mahler European Journal of Pharmaceutics and Biopharmaceutics 70 (1), 42-50, 2008 | 130 | 2008 |
| Oxidative DNA damage and mutations induced by a polar photosensitizer, Ro19-8022 O Will, E Gocke, I Eckert, I Schulz, M Pflaum, HC Mahler, B Epe Mutation Research/DNA Repair 435 (1), 89-101, 1999 | 109 | 1999 |
| Rheological characterization and injection forces of concentrated protein formulations: an alternative predictive model for non-Newtonian solutions A Allmendinger, S Fischer, J Huwyler, HC Mahler, E Schwarb, IE Zarraga, ... European journal of pharmaceutics and biopharmaceutics 87 (2), 318-328, 2014 | 108 | 2014 |
| Surface activity of a monoclonal antibody HC Mahler, F Senner, K Maeder, R Mueller Journal of pharmaceutical sciences 98 (12), 4525-4533, 2009 | 108 | 2009 |
| Selective Oxidation of Methionine and Tryptophan Residues in a Therapeutic I g G 1 Molecule E Folzer, K Diepold, K Bomans, C Finkler, R Schmidt, P Bulau, ... Journal of pharmaceutical sciences 104 (9), 2824-2831, 2015 | 106 | 2015 |
| Highly Concentrated Pharmaceutical Formulations M Adler, HC Mahler, OB Stauch US Patent App. 12/879,486, 2011 | 106 | 2011 |
| Mouse models for assessing protein immunogenicity: lessons and challenges W Jiskoot, G Kijanka, TW Randolph, JF Carpenter, AV Koulov, HC Mahler, ... Journal of pharmaceutical sciences 105 (5), 1567-1575, 2016 | 104 | 2016 |
| Adsorption behavior of a surfactant and a monoclonal antibody to sterilizing-grade filters HC Mahler, F Huber, RSK Kishore, J Reindl, P Rückert, R Müller Journal of pharmaceutical sciences 99 (6), 2620-2627, 2010 | 96 | 2010 |
