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Katherine J. Wert
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Molecular criteria for defining the naive human pluripotent state
TW Theunissen, M Friedli, Y He, E Planet, RC O’Neil, S Markoulaki, ...
Cell stem cell 19 (4), 502-515, 2016
5002016
A Systematic Approach to Identify Candidate Transcription Factors that Control Cell Identity
AC D’Alessio, ZP Fan, KJ Wert, P Baranov, MA Cohen, JS Saini, E Cohick, ...
Stem Cell Reports 5 (5), 763-775, 2015
1722015
Transplantation of reprogrammed embryonic stem cells improves visual function in a mouse model for retinitis pigmentosa
NK Wang, J Tosi, JM Kasanuki, CL Chou, J Kong, N Parmalee, KJ Wert, ...
Transplantation 89 (8), 911-919, 2010
1032010
General pathophysiology in retinal degeneration
KJ Wert, JH Lin, SH Tsang
Cell-Based Therapy for Retinal Degenerative Disease 53, 33-43, 2014
992014
Gene therapy provides long-term visual function in a pre-clinical model of retinitis pigmentosa
KJ Wert, RJ Davis, J Sancho-Pelluz, PM Nishina, SH Tsang
Human molecular genetics 22 (3), 558-567, 2013
802013
Human neural crest cells contribute to coat pigmentation in interspecies chimeras after in utero injection into mouse embryos
MA Cohen, KJ Wert, J Goldmann, S Markoulaki, Y Buganim, D Fu, ...
Proceedings of the National Academy of Sciences 113 (6), 1570-1575, 2016
592016
Extracellular superoxide dismutase (SOD3) regulates oxidative stress at the vitreoretinal interface
KJ Wert, G Velez, MR Cross, BA Wagner, ML Teoh-Fitzgerald, ...
Free Radical Biology and Medicine 124, 408-419, 2018
462018
CAPN5 mutation in hereditary uveitis: the R243L mutation increases calpain catalytic activity and triggers intraocular inflammation in a mouse model
KJ Wert, AG Bassuk, WH Wu, L Gakhar, D Coglan, MA Mahajan, S Wu, ...
Human molecular genetics 24 (16), 4584-4598, 2015
452015
CAPN5 mutation in hereditary uveitis: the R243L mutation increases calpain catalytic activity and triggers intraocular inflammation in a mouse model
KJ Wert, AG Bassuk, WH Wu, L Gakhar, D Coglan, MA Mahajan, S Wu, ...
Human molecular genetics 24 (16), 4584-4598, 2015
452015
Establishment of human pluripotent stem cell-derived pancreatic β-like cells in the mouse pancreas
H Ma, KJ Wert, D Shvartsman, DA Melton, R Jaenisch
Proceedings of the National Academy of Sciences 115 (15), 3924-3929, 2018
432018
Metabolite therapy guided by liquid biopsy proteomics delays retinal neurodegeneration
KJ Wert, G Velez, VL Kanchustambham, V Shankar, LP Evans, ...
EBioMedicine 52, 2020
422020
Functional validation of a human CAPN5 exome variant by lentiviral transduction into mouse retina
KJ Wert, JM Skeie, AG Bassuk, AK Olivier, SH Tsang, VB Mahajan
Human molecular genetics 23 (10), 2665-2677, 2014
412014
Therapeutic margins in a novel preclinical model of retinitis pigmentosa
RJ Davis, CW Hsu, YT Tsai, KJ Wert, J Sancho-Pelluz, CS Lin, SH Tsang
Journal of Neuroscience 33 (33), 13475-13483, 2013
382013
Mid-stage intervention achieves similar efficacy as conventional early-stage treatment using gene therapy in a pre-clinical model of retinitis pigmentosa
KJ Wert, J Sancho-Pelluz, SH Tsang
Human molecular genetics 23 (2), 514-523, 2014
372014
Subretinal injection of gene therapy vectors and stem cells in the perinatal mouse eye
KJ Wert, JM Skeie, RJ Davis, SH Tsang, VB Mahajan
JoVE (Journal of Visualized Experiments), e4286, 2012
372012
Deoxygenation of Aromatic Ketones Using Transfer Hydrogenolysis with Raney Nickel in 2-Propanol
DR Zuidema, SL Williams, KJ Wert, KJ Bosma, AL Smith, RC Mebane
Synthetic Communications 41 (19), 2927-2931, 2011
332011
Neuroretinal hypoxic signaling in a new preclinical murine model for proliferative diabetic retinopathy
KJ Wert, VB Mahajan, L Zhang, Y Yan, Y Li, J Tosi, C Wei Hsu, ...
Signal transduction and targeted therapy 1 (1), 1-10, 2016
272016
Replenishment of TCA cycle intermediates provides photoreceptor resilience against neurodegeneration during progression of retinitis pigmentosa
AA Rowe, PD Patel, R Gordillo, KJ Wert
JCI insight 6 (17), 2021
182021
SILENCING OF TUBERIN ENHANCES PHOTORECEPTOR SURVIVAL AND FUNCTION IN A PRECLINICAL MODEL OF RETINITIS PIGMENTOSA (AN AMERICAN OPHTHALMOLOGICAL SOCIETY THESIS)
MVB Tsang SH, Chan L, Tsai Y, Wu W, Hsu C, Yang J, Tosi J, Wert KJ, Davis RJ
Trans Am Ophthalmol Soc 112, 103-115, 2014
182014
Cytotoxic Escherichia coli strains encoding colibactin isolated from immunocompromised mice with urosepsis and meningitis
V Bakthavatchalu, KJ Wert, Y Feng, A Mannion, Z Ge, A Garcia, KE Scott, ...
PloS one 13 (3), e0194443, 2018
152018
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