Molecular criteria for defining the naive human pluripotent state TW Theunissen, M Friedli, Y He, E Planet, RC O’Neil, S Markoulaki, ... Cell stem cell 19 (4), 502-515, 2016 | 500 | 2016 |
A Systematic Approach to Identify Candidate Transcription Factors that Control Cell Identity AC D’Alessio, ZP Fan, KJ Wert, P Baranov, MA Cohen, JS Saini, E Cohick, ... Stem Cell Reports 5 (5), 763-775, 2015 | 172 | 2015 |
Transplantation of reprogrammed embryonic stem cells improves visual function in a mouse model for retinitis pigmentosa NK Wang, J Tosi, JM Kasanuki, CL Chou, J Kong, N Parmalee, KJ Wert, ... Transplantation 89 (8), 911-919, 2010 | 103 | 2010 |
General pathophysiology in retinal degeneration KJ Wert, JH Lin, SH Tsang Cell-Based Therapy for Retinal Degenerative Disease 53, 33-43, 2014 | 99 | 2014 |
Gene therapy provides long-term visual function in a pre-clinical model of retinitis pigmentosa KJ Wert, RJ Davis, J Sancho-Pelluz, PM Nishina, SH Tsang Human molecular genetics 22 (3), 558-567, 2013 | 80 | 2013 |
Human neural crest cells contribute to coat pigmentation in interspecies chimeras after in utero injection into mouse embryos MA Cohen, KJ Wert, J Goldmann, S Markoulaki, Y Buganim, D Fu, ... Proceedings of the National Academy of Sciences 113 (6), 1570-1575, 2016 | 59 | 2016 |
Extracellular superoxide dismutase (SOD3) regulates oxidative stress at the vitreoretinal interface KJ Wert, G Velez, MR Cross, BA Wagner, ML Teoh-Fitzgerald, ... Free Radical Biology and Medicine 124, 408-419, 2018 | 46 | 2018 |
CAPN5 mutation in hereditary uveitis: the R243L mutation increases calpain catalytic activity and triggers intraocular inflammation in a mouse model KJ Wert, AG Bassuk, WH Wu, L Gakhar, D Coglan, MA Mahajan, S Wu, ... Human molecular genetics 24 (16), 4584-4598, 2015 | 45 | 2015 |
CAPN5 mutation in hereditary uveitis: the R243L mutation increases calpain catalytic activity and triggers intraocular inflammation in a mouse model KJ Wert, AG Bassuk, WH Wu, L Gakhar, D Coglan, MA Mahajan, S Wu, ... Human molecular genetics 24 (16), 4584-4598, 2015 | 45 | 2015 |
Establishment of human pluripotent stem cell-derived pancreatic β-like cells in the mouse pancreas H Ma, KJ Wert, D Shvartsman, DA Melton, R Jaenisch Proceedings of the National Academy of Sciences 115 (15), 3924-3929, 2018 | 43 | 2018 |
Metabolite therapy guided by liquid biopsy proteomics delays retinal neurodegeneration KJ Wert, G Velez, VL Kanchustambham, V Shankar, LP Evans, ... EBioMedicine 52, 2020 | 42 | 2020 |
Functional validation of a human CAPN5 exome variant by lentiviral transduction into mouse retina KJ Wert, JM Skeie, AG Bassuk, AK Olivier, SH Tsang, VB Mahajan Human molecular genetics 23 (10), 2665-2677, 2014 | 41 | 2014 |
Therapeutic margins in a novel preclinical model of retinitis pigmentosa RJ Davis, CW Hsu, YT Tsai, KJ Wert, J Sancho-Pelluz, CS Lin, SH Tsang Journal of Neuroscience 33 (33), 13475-13483, 2013 | 38 | 2013 |
Mid-stage intervention achieves similar efficacy as conventional early-stage treatment using gene therapy in a pre-clinical model of retinitis pigmentosa KJ Wert, J Sancho-Pelluz, SH Tsang Human molecular genetics 23 (2), 514-523, 2014 | 37 | 2014 |
Subretinal injection of gene therapy vectors and stem cells in the perinatal mouse eye KJ Wert, JM Skeie, RJ Davis, SH Tsang, VB Mahajan JoVE (Journal of Visualized Experiments), e4286, 2012 | 37 | 2012 |
Deoxygenation of Aromatic Ketones Using Transfer Hydrogenolysis with Raney Nickel in 2-Propanol DR Zuidema, SL Williams, KJ Wert, KJ Bosma, AL Smith, RC Mebane Synthetic Communications 41 (19), 2927-2931, 2011 | 33 | 2011 |
Neuroretinal hypoxic signaling in a new preclinical murine model for proliferative diabetic retinopathy KJ Wert, VB Mahajan, L Zhang, Y Yan, Y Li, J Tosi, C Wei Hsu, ... Signal transduction and targeted therapy 1 (1), 1-10, 2016 | 27 | 2016 |
Replenishment of TCA cycle intermediates provides photoreceptor resilience against neurodegeneration during progression of retinitis pigmentosa AA Rowe, PD Patel, R Gordillo, KJ Wert JCI insight 6 (17), 2021 | 18 | 2021 |
SILENCING OF TUBERIN ENHANCES PHOTORECEPTOR SURVIVAL AND FUNCTION IN A PRECLINICAL MODEL OF RETINITIS PIGMENTOSA (AN AMERICAN OPHTHALMOLOGICAL SOCIETY THESIS) MVB Tsang SH, Chan L, Tsai Y, Wu W, Hsu C, Yang J, Tosi J, Wert KJ, Davis RJ Trans Am Ophthalmol Soc 112, 103-115, 2014 | 18 | 2014 |
Cytotoxic Escherichia coli strains encoding colibactin isolated from immunocompromised mice with urosepsis and meningitis V Bakthavatchalu, KJ Wert, Y Feng, A Mannion, Z Ge, A Garcia, KE Scott, ... PloS one 13 (3), e0194443, 2018 | 15 | 2018 |