| Network medicine framework for identifying drug-repurposing opportunities for COVID-19 DM Gysi, Í Do Valle, M Zitnik, A Ameli, X Gan, O Varol, SD Ghiassian, ... Proceedings of the National Academy of Sciences 118 (19), 2021 | 420 | 2021 |
| Optimized pipeline of MuTect and GATK tools to improve the detection of somatic single nucleotide polymorphisms in whole-exome sequencing data ÍF do Valle, E Giampieri, G Simonetti, A Padella, M Manfrini, A Ferrari, ... BMC bioinformatics 17 (12), 341, 2016 | 125 | 2016 |
| Acceleration of leukocytes’ epigenetic age as an early tumor and sex-specific marker of breast and colorectal cancer DF Durso, MG Bacalini, C Sala, C Pirazzini, E Marasco, M Bonafé, ... Oncotarget 8 (14), 23237, 2017 | 87 | 2017 |
| RUNX2 expression in thyroid and breast cancer requires the cooperation of three non-redundant enhancers under the control of BRD4 and c-JUN V Sancisi, G Manzotti, M Gugnoni, T Rossi, G Gandolfi, G Gobbi, ... Nucleic acids research 45 (19), 11249-11267, 2017 | 68 | 2017 |
| Network medicine framework shows that proximity of polyphenol targets and disease proteins predicts therapeutic effects of polyphenols IF do Valle, HG Roweth, MW Malloy, S Moco, D Barron, E Battinelli, ... Nature Food 2 (3), 143-155, 2021 | 65 | 2021 |
| The Hippo pathway modulates resistance to BET proteins inhibitors in lung cancer cells G Gobbi, B Donati, IF Do Valle, F Reggiani, F Torricelli, D Remondini, ... Oncogene 38 (42), 6801-6817, 2019 | 64 | 2019 |
| Aneuploid acute myeloid leukemia exhibits a signature of genomic alterations in the cell cycle and protein degradation machinery G Simonetti, A Padella, IF do Valle, MC Fontana, E Fonzi, S Bruno, ... Cancer 125 (5), 712-725, 2019 | 56 | 2019 |
| Systems medicine of inflammaging GC Castellani, G Menichetti, P Garagnani, M Giulia Bacalini, C Pirazzini, ... Briefings in bioinformatics 17 (3), 527-540, 2015 | 45 | 2015 |
| Effect of a low protein diet on chicken ceca microbiome and productive performances A De Cesare, Ì Faria do Valle, C Sala, F Sirri, A Astolfi, G Castellani, ... Poultry Science, 2019 | 44 | 2019 |
| Integrated Molecular Characterization of Gastrointestinal Stromal Tumors (GIST) Harboring the Rare D842V Mutation in PDGFRA Gene V Indio, A Astolfi, G Tarantino, M Urbini, J Patterson, M Nannini, ... International journal of molecular sciences 19 (3), 732, 2018 | 41 | 2018 |
| Clinical validation of a blood-based predictive test for stratification of response to tumor necrosis factor inhibitor therapies in rheumatoid arthritis patients T Mellors, JB Withers, A Ameli, A Jones, M Wang, L Zhang, HN Sanchez, ... Network and Systems Medicine 3 (1), 91-104, 2020 | 35 | 2020 |
| Network integration of multi-tumour omics data suggests novel targeting strategies ÍF do Valle, G Menichetti, G Simonetti, S Bruno, I Zironi, DF Durso, ... Nature communications 9 (1), 4514, 2018 | 34 | 2018 |
| Genomics and phenomics of body mass index reveals a complex disease network J Huang, JE Huffman, Y Huang, Í Do Valle, TL Assimes, S Raghavan, ... Nature Communications, 2022 | 31 | 2022 |
| Comparative modeling of proteins: A method for engaging students' interest in bioinformatics tools F Badotti, AS Barbosa, ALM Reis, ÍF do Valle, L Ambrósio, M Bitar Biochemistry and Molecular Biology Education 42 (1), 68-78, 2014 | 22 | 2014 |
| Stochastic neutral modelling of the Gut Microbiota’s relative species abundance from next generation sequencing data C Sala, S Vitali, E Giampieri, ÌF do Valle, D Remondini, P Garagnani, ... BMC bioinformatics 17 (2), S16, 2016 | 21 | 2016 |
| Aberrant methylation patterns in colorectal cancer: a meta-analysis DF Durso, MG Bacalini, ÍF do Valle, C Pirazzini, M Bonafé, G Castellani, ... Oncotarget 8 (8), 12820, 2017 | 18 | 2017 |
| Application of different DNA extraction procedures, library preparation protocols and sequencing platforms: impact on sequencing results F Pasquali, I Do Valle, F Palma, D Remondini, G Manfreda, G Castellani, ... Heliyon 5 (10), e02745, 2019 | 14 | 2019 |
| Evidence of substantial recombination among Trypanosoma cruzi II strains from Minas Gerais R de Paula Baptista, DA D’Ávila, M Segatto, ÍF do Valle, GR Franco, ... Infection, Genetics and Evolution 22, 183-191, 2014 | 9 | 2014 |
| Recent advances in network medicine: From disease mechanisms to new treatment strategies Í Faria do Valle Multiple Sclerosis Journal, 1352458519877002, 2020 | 8 | 2020 |
| Network-medicine framework for studying disease trajectories in US veterans IF do Valle, B Ferolito, H Gerlovin, L Costa, S Demissie, F Linares, ... Scientific Reports 12 (1), 1-10, 2022 | 7 | 2022 |
