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Haoyun Lei
Haoyun Lei
Bioinformatics Scientist at GRAIL, LLC.
Dirección de correo verificada de andrew.cmu.edu - Página principal
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Functional aging in the nervous system contributes to age-dependent motor activity decline in C. elegans
J Liu, B Zhang, H Lei, Z Feng, J Liu, AL Hsu, XZS Xu
Cell metabolism 18 (3), 392-402, 2013
1382013
The neuronal kinesin UNC-104/KIF1A is a key regulator of synaptic aging and insulin signaling-regulated memory
LB Li, H Lei, RN Arey, P Li, J Liu, CT Murphy, XZS Xu, K Shen
Current Biology 26 (5), 605-615, 2016
612016
Promotion of behavior and neuronal function by reactive oxygen species in C. elegans
G Li, J Gong, H Lei, J Liu, XZS Xu
Nature communications 7 (1), 13234, 2016
532016
Tumor copy number deconvolution integrating bulk and single-cell sequencing data
H Lei, B Lyu, EM Gertz, AA Schäffer, X Shi, K Wu, G Li, L Xu, Y Hou, ...
Journal of Computational Biology 27 (4), 565-598, 2020
182020
Tumor heterogeneity assessed by sequencing and fluorescence in situ hybridization (FISH) data
H Lei, EM Gertz, AA Schäffer, X Fu, Y Tao, K Heselmeyer-Haddad, ...
Bioinformatics 37 (24), 4704-4711, 2021
102021
Robust and accurate deconvolution of tumor populations uncovers evolutionary mechanisms of breast cancer metastasis
Y Tao, H Lei, X Fu, AV Lee, J Ma, R Schwartz
Bioinformatics 36 (Supplement_1), i407-i416, 2020
72020
Reconstructing tumor clonal lineage trees incorporating single-nucleotide variants, copy number alterations and structural variations
X Fu, H Lei, Y Tao, R Schwartz
Bioinformatics 38 (Supplement_1), i125-i133, 2022
62022
Phylogenies derived from matched transcriptome reveal the evolution of cell populations and temporal order of perturbed pathways in breast cancer brain metastases
Y Tao, H Lei, AV Lee, J Ma, R Schwartz
Mathematical and Computational Oncology: First International Symposium …, 2019
52019
Neural network deconvolution method for resolving pathway-level progression of tumor clonal expression programs with application to breast cancer brain metastases
Y Tao, H Lei, AV Lee, J Ma, R Schwartz
Frontiers in physiology 11, 531613, 2020
42020
A clonal evolution simulator for planning somatic evolution studies
A Srivatsa, H Lei, R Schwartz
Journal of Computational Biology 30 (8), 831-847, 2023
32023
Joint clustering of single-cell sequencing and fluorescence in situ hybridization data for reconstructing clonal heterogeneity in cancers
X Fu, H Lei, Y Tao, K Heselmeyer-Haddad, I Torres, M Dean, T Ried, ...
Journal of Computational Biology 28 (11), 1035-1051, 2021
32021
Semi-deconvolution of bulk and single-cell RNA-seq data with application to metastatic progression in breast cancer
H Lei, XA Guo, Y Tao, K Ding, X Fu, S Oesterreich, AV Lee, R Schwartz
Bioinformatics 38 (Supplement_1), i386-i394, 2022
12022
A simulator for somatic evolution study design
A Srivatsa, H Lei, R Schwartz
bioRxiv, 2022.05. 01.487551, 2022
12022
Improved deconvolution of combined bulk and single-cell RNA-sequencing data
H Lei, XA Guo, Y Tao, K Ding, X Fu, S Oesterreich, AV Lee, R Schwartz
Cancer Research 82 (12_Supplement), 5031-5031, 2022
2022
Deconvolution of copy number alterations combining bulk and single-cell genomic data
H Lei, B Lyu, EM Gertz, AA Schaeffer, X Shi, K Wu, G Li, L Xu, Y Hou, ...
Cancer Research 79 (13_Supplement), 1650-1650, 2019
2019
Tumor Copy Number Data Deconvolution Integrating Bulk and Single-cell Sequencing Data
H Lei, B Lyu, EM Gertz, AA Schaffer, R Schwartz
2018 IEEE 8th International Conference on Computational Advances in Bio and …, 2018
2018
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