| Coexistence of multivalent and monovalent TCRs explains high sensitivity and wide range of response WWA Schamel, I Arechaga, RM Risueño, HM van Santen, P Cabezas, ... The Journal of experimental medicine 202 (4), 493-503, 2005 | 371 | 2005 |
| Antigen persistence is required throughout the expansion phase of a CD4+ T cell response R Obst, HM van Santen, D Mathis, C Benoist The Journal of experimental medicine 201 (10), 1555-1565, 2005 | 371 | 2005 |
| Number of T reg cells that differentiate does not increase upon encounter of agonist ligand on thymic epithelial cells HM van Santen, C Benoist, D Mathis The Journal of experimental medicine 200 (10), 1221-1230, 2004 | 323 | 2004 |
| Major histocompatibility class I presentation of soluble antigen facilitated by Mycobacterium tuberculosis infection RJ Mazzaccaro, M Gedde, ER Jensen, HM Van Santen, HL Ploegh, ... Proceedings of the National Academy of Sciences 93 (21), 11786-11791, 1996 | 234 | 1996 |
| Increased sensitivity of antigen-experienced T cells through the enrichment of oligomeric T cell receptor complexes R Kumar, M Ferez, M Swamy, I Arechaga, MT Rejas, JM Valpuesta, ... Immunity 35 (3), 375-387, 2011 | 202 | 2011 |
| Misfolded major histocompatibility complex class I molecules accumulate in an expanded ER-Golgi intermediate compartment. G Raposo, HM van Santen, R Leijendekker, HJ Geuze, HL Ploegh The Journal of cell biology 131 (6), 1403-1419, 1995 | 146 | 1995 |
| Peptide-induced stabilization and intracellular localization of empty HLA class I complexes. EJ Baas, HM van Santen, MJ Kleijmeer, HJ Geuze, PJ Peters, HL Ploegh The Journal of experimental medicine 176 (1), 147-156, 1992 | 126 | 1992 |
| T‐cell antigen‐receptor stoichiometry: pre‐clustering for sensitivity B Alarcón, M Swamy, HM van Santen, WWA Schamel EMBO reports 7 (5), 490-495, 2006 | 103 | 2006 |
| Sustained antigen presentation can promote an immunogenic T cell response, like dendritic cell activation R Obst, HM van Santen, R Melamed, AO Kamphorst, C Benoist, D Mathis Proceedings of the National Academy of Sciences 104 (39), 15460-15465, 2007 | 100 | 2007 |
| A conformational change senses the strength of T cell receptor–ligand interaction during thymic selection RM Risueño, HM Van Santen, B Alarcón Proceedings of the National Academy of Sciences 103 (25), 9625-9630, 2006 | 48 | 2006 |
| Flow cytometry multiplexed method for the detection of neutralizing human antibodies to the native SARS‐CoV‐2 spike protein L Horndler, P Delgado, D Abia, I Balabanov, P Martínez‐Fleta, G Cornish, ... EMBO molecular medicine 13 (3), e13549, 2021 | 36 | 2021 |
| Increase in positive selection of CD8+ T cells in TAP1-mutant mice by human beta 2-microglobulin transgene. H Martien van Santen, A Woolsey, PG Rickardt, L Van Kaer, EJ Baas, ... The Journal of experimental medicine 181 (2), 787-792, 1995 | 33 | 1995 |
| Receptor pre-clustering and T cell responses: insights into molecular mechanisms M Castro, HM van Santen, M Férez, B Alarcón, G Lythe, C Molina-París Frontiers in immunology 5, 132, 2014 | 32 | 2014 |
| Two receptors, two kinases, and T cell lineage determination B Alarcón, HM Van Santen Science signaling 3 (114), pe11-pe11, 2010 | 30 | 2010 |
| Alterations in dendritic cell phenotype and function associated with immunoenhancing effects of a subcutaneously administered cyclophosphamide derivative KG Limpens J, Van Meijer M, Van Santen HM, Germeraad WT, Hoeben-Schornagel K ... Immunology 73 (3), 255-263, 1991 | 30 | 1991 |
| Cognate peptide–MHC complexes are expressed as tightly apposed nanoclusters in virus-infected cells to allow TCR crosslinking M Ferez, M Castro, B Alarcon, HM van Santen The Journal of Immunology 192 (1), 52-58, 2014 | 28 | 2014 |
| Models of self-peptide sampling by developing T cells identify candidate mechanisms of thymic selection I Bains, HM van Santen, B Seddon, AJ Yates PLoS computational biology 9 (7), e1003102, 2013 | 28 | 2013 |
| A cassette vector for high-level reporter expression driven by a hybrid invariant chain promoter in transgenic mice HM van Santen, C Benoist, D Mathis Journal of immunological methods 245 (1), 133-137, 2000 | 27 | 2000 |
| Biosynthesis of major histocompatibility complex molecules and generation of T cells in Ii TAP1 double-mutant mice S Tourne, HM Van Santen, M Van Roon, A Berns, C Benoist, D Mathis, ... Proceedings of the National Academy of Sciences 93 (4), 1464-1469, 1996 | 26 | 1996 |
| CCR5 deficiency impairs CD4+ T‐cell memory responses and antigenic sensitivity through increased ceramide synthesis A Martín‐Leal, R Blanco, J Casas, ME Sáez, E Rodríguez‐Bovolenta, ... The EMBO journal 39 (15), e104749, 2020 | 19 | 2020 |
