Brian Kuhlman
Brian Kuhlman
Dirección de correo verificada de email.unc.edu
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Design of a novel globular protein fold with atomic-level accuracy
B Kuhlman, G Dantas, GC Ireton, G Varani, BL Stoddard, D Baker
science 302 (5649), 1364-1368, 2003
16342003
ROSETTA3: an object-oriented software suite for the simulation and design of macromolecules
A Leaver-Fay, M Tyka, SM Lewis, OF Lange, J Thompson, R Jacak, ...
Methods in enzymology 487, 545-574, 2011
11812011
Protein–protein docking with simultaneous optimization of rigid-body displacement and side-chain conformations
JJ Gray, S Moughon, C Wang, O Schueler-Furman, B Kuhlman, CA Rohl, ...
Journal of molecular biology 331 (1), 281-299, 2003
10392003
A genetically encoded photoactivatable Rac controls the motility of living cells
YI Wu, D Frey, OI Lungu, A Jaehrig, I Schlichting, B Kuhlman, KM Hahn
Nature 461 (7260), 104-108, 2009
9042009
Native protein sequences are close to optimal for their structures
B Kuhlman, D Baker
Proceedings of the National Academy of Sciences 97 (19), 10383-10388, 2000
8342000
A large scale test of computational protein design: folding and stability of nine completely redesigned globular proteins
G Dantas, B Kuhlman, D Callender, M Wong, D Baker
Journal of molecular biology 332 (2), 449-460, 2003
3452003
Labelling and optical erasure of synaptic memory traces in the motor cortex
A Hayashi-Takagi, S Yagishita, M Nakamura, F Shirai, YI Wu, ...
Nature 525 (7569), 333-338, 2015
3372015
The Rosetta all-atom energy function for macromolecular modeling and design
RF Alford, A Leaver-Fay, JR Jeliazkov, MJ O’Meara, FP DiMaio, H Park, ...
Journal of chemical theory and computation 13 (6), 3031-3048, 2017
2592017
Computer-based redesign of a protein folding pathway
S Nauli, B Kuhlman, D Baker
Nature structural biology 8 (7), 602-605, 2001
2472001
Engineering an improved light-induced dimer (iLID) for controlling the localization and activity of signaling proteins
G Guntas, RA Hallett, SP Zimmerman, T Williams, H Yumerefendi, ...
Proceedings of the National Academy of Sciences 112 (1), 112-117, 2015
2412015
Mice fed a lipogenic methionine-choline-deficient diet develop hypermetabolism coincident with hepatic suppression of SCD-1
G Rizki, L Arnaboldi, B Gabrielli, J Yan, GS Lee, RK Ng, SM Turner, ...
Journal of lipid research 47 (10), 2280-2290, 2006
2112006
Serverification of molecular modeling applications: the Rosetta Online Server that Includes Everyone (ROSIE)
S Lyskov, FC Chou, SÓ Conchúir, BS Der, K Drew, D Kuroda, J Xu, ...
PloS one 8 (5), 2013
2062013
An improved protein decoy set for testing energy functions for protein structure prediction
J Tsai, R Bonneau, AV Morozov, B Kuhlman, CA Rohl, D Baker
Proteins: Structure, Function, and Bioinformatics: Structure, Function, and …, 2003
1932003
RosettaDesign server for protein design
Y Liu, B Kuhlman
Nucleic acids research 34 (suppl_2), W235-W238, 2006
1832006
E2 conjugating enzymes must disengage from their E1 enzymes before E3-dependent ubiquitin and ubiquitin-like transfer
ZM Eletr, DT Huang, DM Duda, BA Schulman, B Kuhlman
Nature structural & molecular biology 12 (10), 933-934, 2005
1822005
Computational design of a single amino acid sequence that can switch between two distinct protein folds
XI Ambroggio, B Kuhlman
Journal of the American Chemical Society 128 (4), 1154-1161, 2006
1712006
Generation of bispecific IgG antibodies by structure-based design of an orthogonal Fab interface
SM Lewis, X Wu, A Pustilnik, A Sereno, F Huang, HL Rick, G Guntas, ...
Nature biotechnology 32 (2), 191, 2014
1662014
Scientific benchmarks for guiding macromolecular energy function improvement
A Leaver-Fay, MJ O'Meara, M Tyka, R Jacak, Y Song, EH Kellogg, ...
Methods in enzymology 523, 109-143, 2013
1662013
Rapid E2-E3 assembly and disassembly enable processive ubiquitylation of cullin-RING ubiquitin ligase substrates
G Kleiger, A Saha, S Lewis, B Kuhlman, RJ Deshaies
Cell 139 (5), 957-968, 2009
1572009
Combined covalent-electrostatic model of hydrogen bonding improves structure prediction with Rosetta
MJ O’Meara, A Leaver-Fay, MD Tyka, A Stein, K Houlihan, F DiMaio, ...
Journal of chemical theory and computation 11 (2), 609-622, 2015
1512015
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