Alfonso Mora (orcid: 0000-0002-6397-4836)
Alfonso Mora (orcid: 0000-0002-6397-4836)
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PDK1, the master regulator of AGC kinase signal transduction
A Mora, D Komander, DMF van Aalten, DR Alessi
Seminars in cell & developmental biology 15 (2), 161-170, 2004
A stress signaling pathway in adipose tissue regulates hepatic insulin resistance
G Sabio, M Das, A Mora, Z Zhang, JY Jun, HJ Ko, T Barrett, JK Kim, ...
Science 322 (5907), 1539-1543, 2008
Essential role of PDK1 in regulating cell size and development in mice
MA Lawlor, A Mora, PR Ashby, MR Williams, V Murray‐Tait, L Malone, ...
The EMBO journal 21 (14), 3728-3738, 2002
Deficiency of PDK1 in cardiac muscle results in heart failure and increased sensitivity to hypoxia
A Mora, AM Davies, L Bertrand, I Sharif, GR Budas, S Jovanović, ...
The EMBO journal 22 (18), 4666-4676, 2003
Crystal structure of human arginase I at 1.29-Å resolution and exploration of inhibition in the immune response
L Di Costanzo, G Sabio, A Mora, PC Rodriguez, AC Ochoa, F Centeno, ...
Proceedings of the National Academy of Sciences 102 (37), 13058-13063, 2005
Prevention of steatosis by hepatic JNK1
G Sabio, J Cavanagh-Kyros, HJ Ko, DY Jung, S Gray, JY Jun, T Barrett, ...
Cell Metabolism 10 (6), 491-498, 2009
Different mechanisms of protection against apoptosis by valproate and Li+
A Mora, RA González‐Polo, JM Fuentes, G Soler, F Centeno
European Journal of Biochemistry 266 (3), 886-891, 1999
Lithium inhibits caspase 3 activation and dephosphorylation of PKB and GSK3 induced by K+ deprivation in cerebellar granule cells
A Mora, G Sabio, RA González‐Polo, A Cuenda, DR Alessi, JC Alonso, ...
Journal of neurochemistry 78 (1), 199-206, 2001
Lithium blocks the PKB and GSK3 dephosphorylation induced by ceramide through protein phosphatase-2A
A Mora, G Sabio, AM Risco, A Cuenda, JC Alonso, G Soler, F Centeno
Cellular signalling 14 (6), 557-562, 2002
Role of the hypothalamic–pituitary–thyroid axis in metabolic regulation by JNK1
G Sabio, J Cavanagh-Kyros, T Barrett, DY Jung, HJ Ko, H Ong, C Morel, ...
Genes & development 24 (3), 256-264, 2010
Deficiency of PDK1 in liver results in glucose intolerance, impairment of insulin-regulated gene expression and liver failure
A Mora, C Lipina, F Tronche, C Sutherland, DR Alessi
Biochemical Journal 385 (3), 639-648, 2005
Role of the PDK1–PKB–GSK3 pathway in regulating glycogen synthase and glucose uptake in the heart
A Mora, K Sakamoto, EJ McManus, DR Alessi
FEBS letters 579 (17), 3632-3638, 2005
Partial lithium-associated protection against apoptosis induced by C2-ceramide in cerebellar granule neurons
F Centeno, A Mora, JM Fuentes, G Soler, E Claro
Neuroreport 9 (18), 4199-4203, 1998
Identification of filamin C as a new physiological substrate of PKBα using KESTREL
JT Murray, DG Campbell, M Peggie, M Alfonso, P Cohen
Biochemical Journal 384 (3), 489-494, 2004
Different dependence of lithium and valproate on PI3K/PKB pathway
A Mora, G Sabio, JC Alonso, G Soler, F Centeno
Bipolar disorders 4 (3), 195-200, 2002
Mechanisms of MPP+ incorporation into cerebellar granule cells
RA González-Polo, A Mora, N Clemente, G Sabio, F Centeno, G Soler, ...
Brain research bulletin 56 (2), 119-123, 2001
p38γ and p38δ reprogram liver metabolism by modulating neutrophil infiltration
B González‐Terán, N Matesanz, I Nikolic, MA Verdugo, V Sreeramkumar, ...
The EMBO journal 35 (5), 536-552, 2016
p38γ is essential for cell cycle progression and liver tumorigenesis
A Tomás-Loba, E Manieri, B González-Terán, A Mora, L Leiva-Vega, ...
Nature 568 (7753), 557-560, 2019
Implications of the S-shaped domain in the quaternary structure of human arginase
A Mora, M del Ara Rangel, JM Fuentes, G Soler, F Centeno
Biochimica et Biophysica Acta (BBA)-Protein Structure and Molecular …, 2000
Glu-256 is a main structural determinant for oligomerisation of human arginase I
G Sabio, A Mora, MA Rangel, A Quesada, CF Marcos, JC Alonso, G Soler, ...
FEBS letters 501 (2-3), 161-165, 2001
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