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Pankaj K Singh
Pankaj K Singh
Professor and Chair, Department of Oncology Science, OUHSC
Dirección de correo verificada de ouhsc.edu
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Sonic hedgehog promotes desmoplasia in pancreatic cancer
JM Bailey, BJ Swanson, T Hamada, JP Eggers, PK Singh, T Caffery, ...
Clinical cancer research 14 (19), 5995-6004, 2008
6262008
Combination of ERK and autophagy inhibition as a treatment approach for pancreatic cancer
KL Bryant, CA Stalnecker, D Zeitouni, JE Klomp, S Peng, AP Tikunov, ...
Nature medicine 25 (4), 628-640, 2019
5652019
Cell surface-associated mucins in signal transduction
PK Singh, MA Hollingsworth
Trends in cell biology 16 (9), 467-476, 2006
5022006
MUC1 and HIF-1alpha Signaling Crosstalk Induces Anabolic Glucose Metabolism to Impart Gemcitabine Resistance to Pancreatic Cancer
SK Shukla, V Purohit, K Mehla, V Gunda, NV Chaika, E Vernucci, RJ King, ...
Cancer Cell 32 (1), 71-87. e7, 2017
4602017
Metabolic regulation of macrophage polarization in cancer
K Mehla, PK Singh
Trends in cancer 5 (12), 822-834, 2019
3202019
Cancer metastasis facilitated by developmental pathways: Sonic hedgehog, Notch, and bone morphogenic proteins
JM Bailey, PK Singh, MA Hollingsworth
Journal of cellular biochemistry 102 (4), 829-839, 2007
2952007
Metabolic reprogramming induced by ketone bodies diminishes pancreatic cancer cachexia
SK Shukla, T Gebregiworgis, V Purohit, NV Chaika, V Gunda, ...
Cancer & metabolism 2 (1), 18, 2014
2462014
Graviola: a novel promising natural-derived drug that inhibits tumorigenicity and metastasis of pancreatic cancer cells in vitro and in vivo through altering cell metabolism
MP Torres, S Rachagani, V Purohit, P Pandey, S Joshi, ED Moore, ...
Cancer letters 323 (1), 29-40, 2012
2432012
MUC1 mucin stabilizes and activates hypoxia-inducible factor 1 alpha to regulate metabolism in pancreatic cancer
NV Chaika, T Gebregiworgis, ME Lewallen, V Purohit, P Radhakrishnan, ...
Proceedings of the National Academy of Sciences 109 (34), 13787-13792, 2012
2292012
MUC4 mucin interacts with and stabilizes the HER2 oncoprotein in human pancreatic cancer cells
P Chaturvedi, AP Singh, S Chakraborty, SC Chauhan, S Bafna, JL Meza, ...
Cancer research 68 (7), 2065-2070, 2008
1902008
De Novo Lipid Synthesis Facilitates Gemcitabine Resistance through Endoplasmic Reticulum Stress in Pancreatic Cancer
S Tadros, SK Shukla, RJ King, V Gunda, E Vernucci, J Abrego, NV Chaika, ...
Cancer Research 77 (20), 5503-5517, 2017
1772017
CRTC3 links catecholamine signalling to energy balance
Y Song, J Altarejos, MO Goodarzi, H Inoue, X Guo, R Berdeaux, JH Kim, ...
Nature 468 (7326), 933-939, 2010
1742010
The distinct metabolic phenotype of lung squamous cell carcinoma defines selective vulnerability to glycolytic inhibition
J Goodwin, ML Neugent, SY Lee, JH Choe, H Choi, DMR Jenkins, ...
Nature communications 8 (1), 15503, 2017
1502017
O-GlcNAc transferase suppresses inflammation and necroptosis by targeting receptor-interacting serine/threonine-protein kinase 3
X Li, W Gong, H Wang, T Li, KS Attri, RE Lewis, AC Kalil, F Bhinderwala, ...
Immunity 50 (3), 576-590. e6, 2019
1432019
Platelet-Derived Growth Factor Receptor β–Mediated Phosphorylation of MUC1 Enhances Invasiveness in Pancreatic Adenocarcinoma Cells
PK Singh, Y Wen, BJ Swanson, K Shanmugam, A Kazlauskas, RL Cerny, ...
Cancer research 67 (11), 5201-5210, 2007
1382007
RNA interference suppression of MUC1 reduces the growth rate and metastatic phenotype of human pancreatic cancer cells
H Tsutsumida, BJ Swanson, PK Singh, TC Caffrey, S Kitajima, M Goto, ...
Clinical cancer research 12 (10), 2976-2987, 2006
1362006
Amino acid transporter SLC6A14 is a novel and effective drug target for pancreatic cancer
V Coothankandaswamy, S Cao, Y Xu, PD Prasad, PK Singh, ...
British Journal of Pharmacology 173 (23), 3292-3306, 2016
1282016
Cyclin-Dependent Kinase 5 Is Amplified and Overexpressed in Pancreatic Cancer and Activated by Mutant K-Ras
JP Eggers, PM Grandgenett, EC Collisson, ME Lewallen, J Tremayne, ...
Clinical Cancer Research 17 (19), 6140-6150, 2011
1212011
Targeting Hypoxia-Inducible Factor-1α/Pyruvate Dehydrogenase Kinase 1 Axis by Dichloroacetate Suppresses Bleomycin-induced Pulmonary Fibrosis
J Goodwin, H Choi, M Hsieh, ML Neugent, JM Ahn, HN Hayenga, ...
American journal of respiratory cell and molecular biology 58 (2), 216-231, 2018
1182018
MUC1 is a counter-receptor for myelin-associated glycoprotein (Siglec-4a) and their interaction contributes to adhesion in pancreatic cancer perineural invasion
BJ Swanson, KM McDermott, PK Singh, JP Eggers, PR Crocker, ...
Cancer research 67 (21), 10222-10229, 2007
1172007
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