| Alzheimer mechanisms and therapeutic strategies Y Huang, L Mucke Cell 148 (6), 1204-1222, 2012 | 2141 | 2012 |
| Apolipoprotein E4: a causative factor and therapeutic target in neuropathology, including Alzheimer’s disease RW Mahley, KH Weisgraber, Y Huang Proceedings of the National Academy of Sciences 103 (15), 5644-5651, 2006 | 1220 | 2006 |
| High-density lipoprotein cholesterol as a predictor of coronary heart disease risk. The PROCAM experience and pathophysiological implications for reverse cholesterol transport G Assmann, H Schulte, A von Eckardstein, Y Huang Atherosclerosis 124, S11-S20, 1996 | 976 | 1996 |
| ApoE genotype accounts for the vast majority of AD risk and AD pathology J Raber, Y Huang, JW Ashford Neurobiology of aging 25 (5), 641-650, 2004 | 773 | 2004 |
| Apolipoprotein E: structure and function in lipid metabolism, neurobiology, and Alzheimer's diseases Y Huang, RW Mahley Neurobiology of disease 72, 3-12, 2014 | 715 | 2014 |
| Direct reprogramming of mouse and human fibroblasts into multipotent neural stem cells with a single factor KL Ring, LM Tong, ME Balestra, R Javier, Y Andrews-Zwilling, G Li, ... Cell stem cell 11 (1), 100-109, 2012 | 644 | 2012 |
| Apolipoprotein E: structure determines function, from atherosclerosis to Alzheimer's disease to AIDS RW Mahley, KH Weisgraber, Y Huang Journal of lipid research 50, S183-S188, 2009 | 639 | 2009 |
| Pathogenesis of type III hyperlipoproteinemia (dysbetalipoproteinemia): questions, quandaries, and paradoxes RW Mahley, Y Huang, SC Rall Journal of lipid research 40 (11), 1933-1949, 1999 | 565 | 1999 |
| Profile and regulation of apolipoprotein E (ApoE) expression in the CNS in mice with targeting of green fluorescent protein gene to the ApoE locus Q Xu, A Bernardo, D Walker, T Kanegawa, RW Mahley, Y Huang Journal of Neuroscience 26 (19), 4985-4994, 2006 | 539 | 2006 |
| Kynurenine 3-monooxygenase inhibition in blood ameliorates neurodegeneration D Zwilling, SY Huang, KV Sathyasaikumar, FM Notarangelo, P Guidetti, ... Cell 145 (6), 863-874, 2011 | 520 | 2011 |
| Neuron-specific apolipoprotein e4 proteolysis is associated with increased tau phosphorylation in brains of transgenic mice WJ Brecht, FM Harris, S Chang, I Tesseur, GQ Yu, Q Xu, JD Fish, ... Journal of Neuroscience 24 (10), 2527-2534, 2004 | 502 | 2004 |
| Apolipoprotein E: from atherosclerosis to Alzheimer's disease and beyond RW Mahley, Y Huang Current opinion in lipidology 10 (3), 207-218, 1999 | 499 | 1999 |
| Apolipoprotein E fragments present in Alzheimer's disease brains induce neurofibrillary tangle-like intracellular inclusions in neurons Y Huang, XQ Liu, T Wyss-Coray, WJ Brecht, DA Sanan, RW Mahley Proceedings of the National Academy of Sciences 98 (15), 8838-8843, 2001 | 472 | 2001 |
| Carboxyl-terminal-truncated apolipoprotein E4 causes Alzheimer's disease-like neurodegeneration and behavioral deficits in transgenic mice FM Harris, WJ Brecht, Q Xu, I Tesseur, L Kekonius, T Wyss-Coray, JD Fish, ... Proceedings of the National Academy of Sciences 100 (19), 10966-10971, 2003 | 433 | 2003 |
| Apolipoprotein e sets the stage: response to injury triggers neuropathology RW Mahley, Y Huang Neuron 76 (5), 871-885, 2012 | 411 | 2012 |
| Apolipoprotein E4 causes age-and Tau-dependent impairment of GABAergic interneurons, leading to learning and memory deficits in mice Y Andrews-Zwilling, N Bien-Ly, Q Xu, G Li, A Bernardo, SY Yoon, ... Journal of Neuroscience 30 (41), 13707-13717, 2010 | 356 | 2010 |
| Apolipoprotein (apo) E4 enhances amyloid β peptide production in cultured neuronal cells: ApoE structure as a potential therapeutic target S Ye, Y Huang, K Müllendorff, L Dong, G Giedt, EC Meng, FE Cohen, ... Proceedings of the National Academy of Sciences 102 (51), 18700-18705, 2005 | 355 | 2005 |
| Gain of toxic apolipoprotein E4 effects in human iPSC-derived neurons is ameliorated by a small-molecule structure corrector C Wang, R Najm, Q Xu, D Jeong, D Walker, ME Balestra, SY Yoon, ... Nature medicine 24 (5), 647-657, 2018 | 326 | 2018 |
| GABAergic interneuron dysfunction impairs hippocampal neurogenesis in adult apolipoprotein E4 knockin mice G Li, N Bien-Ly, Y Andrews-Zwilling, Q Xu, A Bernardo, K Ring, ... Cell stem cell 5 (6), 634-645, 2009 | 287 | 2009 |
| Lipid-and receptor-binding regions of apolipoprotein E4 fragments act in concert to cause mitochondrial dysfunction and neurotoxicity S Chang, T Ma, RD Miranda, ME Balestra, RW Mahley, Y Huang Proceedings of the National Academy of Sciences 102 (51), 18694-18699, 2005 | 285 | 2005 |
