| Systemic administration of a bispecific antibody targeting EGFRvIII successfully treats intracerebral glioma BD Choi, CT Kuan, M Cai, GE Archer, DA Mitchell, PC Gedeon, ... Proceedings of the National Academy of Sciences 110 (1), 270-275, 2013 | 169 | 2013 |
| Intracerebral delivery of a third generation EGFRvIII-specific chimeric antigen receptor is efficacious against human glioma BD Choi, CM Suryadevara, PC Gedeon, JE Herndon II, L Sanchez-Perez, ... Journal of Clinical Neuroscience 21 (1), 189-190, 2014 | 126* | 2014 |
| Dendritic Cells Enhance Polyfunctionality of Adoptively Transferred T Cells That Target Cytomegalovirus in Glioblastoma EA Reap, CM Suryadevara, KA Batich, L Sanchez-Perez, GE Archer, ... Cancer research 78 (1), 256-264, 2018 | 101 | 2018 |
| Temozolomide lymphodepletion enhances CAR abundance and correlates with antitumor efficacy against established glioblastoma CM Suryadevara, R Desai, ML Abel, KA Riccione, KA Batich, SH Shen, ... OncoImmunology 7 (6), e1434464, 2018 | 88 | 2018 |
| Are BiTEs the ‘missing link’ in cancer therapy? CM Suryadevara, PC Gedeon, L Sanchez-Perez, T Verla, ... OncoImmunology 4 (6), e1008339, 2015 | 82 | 2015 |
| Human regulatory T cells kill tumor cells through granzyme-dependent cytotoxicity upon retargeting with a bispecific antibody BD Choi, PC Gedeon, JE Herndon, GE Archer, EA Reap, ... Cancer Immunology Research 1 (3), 163-167, 2013 | 78* | 2013 |
| Preventing Lck Activation in CAR T Cells Confers Treg Resistance but Requires 4-1BB Signaling for Them to Persist and Treat Solid Tumors in Nonlymphodepleted Hosts CM Suryadevara, R Desai, SH Farber, BD Choi, AM Swartz, SH Shen, ... Clinical Cancer Research 25 (1), 358-368, 2019 | 59 | 2019 |
| Molecular dynamics of leucine and dopamine transporter proteins in a model cell membrane lipid bilayer PC Gedeon, M Indarte, CK Surratt, JD Madura Proteins: Structure, Function, and Bioinformatics 78 (4), 797-811, 2010 | 47 | 2010 |
| A rationally designed fully human EGFRvIII:CD3-targeted bispecific antibody redirects human T cells to treat patient-derived intracerebral malignant glioma PC Gedeon, TH Schaller, SK Chitneni, BD Choi, CT Kuan, ... Clinical Cancer Research 24 (15), 3611-3631, 2018 | 45 | 2018 |
| Regulatory T cells are redirected to kill glioblastoma by an EGFRvIII-targeted bispecific antibody BD Choi, PC Gedeon, L Sanchez-Perez, DD Bigner, JH Sampson OncoImmunology 2 (12), e26757, 2013 | 43 | 2013 |
| Epidermal growth factor receptor and variant III targeted immunotherapy KL Congdon, PC Gedeon, CM Suryadevara, HG Caruso, LJN Cooper, ... Neuro-oncology 16 (suppl_8), viii20-viii25, 2014 | 42 | 2014 |
| LeuT conformational sampling utilizing accelerated molecular dynamics and principal component analysis JR Thomas, PC Gedeon, BJ Grant, JD Madura Biophysical Journal 103 (1), L1-L3, 2012 | 33 | 2012 |
| An EGFRvIII-targeted bispecific T-cell engager overcomes limitations of the standard of care for glioblastoma PC Gedeon, BD Choi, TR Hodges, DA Mitchell, DD Bigner, JH Sampson Expert Review of Clinical Pharmacology 6 (4), 375-386, 2013 | 32 | 2013 |
| Accelerated molecular dynamics and protein conformational change: a theoretical and practical guide using a membrane embedded model neurotransmitter transporter PC Gedeon, JR Thomas, JD Madura Methods in Molecular Biology 1215, 253-287, 2015 | 31 | 2015 |
| Rindopepimut: anti-EGFRvIII peptide vaccine, oncolytic PC Gedeon, BD Choi, JH Sampson, DD Bigner Drugs of the Future 38 (3), 147-155, 2013 | 30 | 2013 |
| First in human dose calculation of a single-chain bispecific antibody targeting glioma using the MABEL approach TH Schaller, DJ Snyder, I Spasojevic, PC Gedeon, L Sanchez-Perez, ... Journal for Immunotherapy of Cancer 8 (1), e000213, 2020 | 23 | 2020 |
| Antibody-Based Immunotherapy for Malignant Glioma PC Gedeon, KA Riccione, PE Fecci, JH Sampson Seminars in Oncology 41 (4), 496-510, 2014 | 18 | 2014 |
| Checkpoint inhibitor immunotherapy for glioblastoma: current progress, challenges and future outlook PC Gedeon, CD Champion, KE Rhodin, K Woroniecka, HR Kemeny, ... Expert Review of Clinical Pharmacology 13 (10), 1147-1158, 2020 | 10 | 2020 |
| Certain Improved Human Bispecific EGFRvIII Antibody Engaging Molecules DD Bigner, J Sampson, CT Kuan, CAI Mingqing, PC Gedeon, IH Pastan US Patent 10,053,514, 2018 | 7* | 2018 |
| Rational design and generation of recombinant control reagents for bispecific antibodies through CDR mutagenesis BD Choi, PC Gedeon, CT Kuan, L Sanchez-Perez, GE Archer, DD Bigner, ... Journal of immunological methods 395 (1-2), 14-20, 2013 | 7 | 2013 |
John H. Sampson, M.D., Ph.D., M.H.Sc...Wilkins Distinguished Professor and Chief of NeurosurgeryVerified email at duke.edu
