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George Dakwar, PhD
George Dakwar, PhD
Director, Formulation Platform at CureVac
Dirección de correo verificada de curevac.com
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Nanomedicine-based intraperitoneal therapy for the treatment of peritoneal carcinomatosis—Mission possible?
GR Dakwar, M Shariati, W Willaert, W Ceelen, SC De Smedt, K Remaut
Advanced drug delivery reviews 108, 13-24, 2017
1092017
Colloidal stability of nano-sized particles in the peritoneal fluid: towards optimizing drug delivery systems for intraperitoneal therapy
GR Dakwar, E Zagato, J Delanghe, S Hobel, A Aigner, H Denys, ...
Acta Biomaterialia 10 (7), 2965-2975, 2014
772014
Delivery of proteins to the brain by bolaamphiphilic nano-sized vesicles
GR Dakwar, IA Hammad, M Popov, C Linder, S Grinberg, E Heldman, ...
Journal of controlled release 160 (2), 315-321, 2012
672012
Decationized polyplexes as stable and safe carrier systems for improved biodistribution in systemic gene therapy
L Novo, LY Rizzo, SK Golombek, GR Dakwar, B Lou, K Remaut, ...
Journal of controlled release 195, 162-175, 2014
452014
Design of smart GE11-PLGA/PEG-PLGA blend nanoparticulate platforms for parenteral administration of hydrophilic macromolecular drugs: synthesis, preparation and in vitro/ex …
B Colzani, G Speranza, R Dorati, B Conti, T Modena, G Bruni, E Zagato, ...
International journal of pharmaceutics 511 (2), 1112-1123, 2016
432016
Freeze-dried mucoadhesive polymeric system containing pegylated lipoplexes: Towards a vaginal sustained released system for siRNA
T Furst, GR Dakwar, E Zagato, A Lechanteur, K Remaut, B Evrard, ...
Journal of controlled release 236, 68-78, 2016
372016
High‐pressure nebulization as application route for the peritoneal administration of siRNA complexes
AK Minnaert, GR Dakwar, JM Benito, JM García Fernández, W Ceelen, ...
Macromolecular bioscience 17 (10), 1700024, 2017
352017
Disregarded effect of biological fluids in siRNA delivery: human ascites fluid severely restricts cellular uptake of nanoparticles
GR. Dakwar, K. Braeckmans, J. Demeester, W. Ceelen, S.C. De Smedt
ACS APPLIED MATERIALS & INTERFACES 7 (43), 24322-24329, 2015
352015
Bolaamphiphilic vesicles encapsulating iron oxide nanoparticles: New vehicles for magnetically targeted drug delivery
L Philosof-Mazor, GR Dakwar, M Popov, S Kolusheva, A Shames, ...
International journal of pharmaceutics 450 (1-2), 241-249, 2013
342013
Intracellular delivery of oligonucleotides in Helicobacter pylori by fusogenic liposomes in the presence of gastric mucus
RS Santos, GR Dakwar, E Zagato, T Brans, C Figueiredo, K Raemdonck, ...
Biomaterials 138, 1-12, 2017
292017
Targeted decationized polyplexes for siRNA delivery
L Novo, KM Takeda, T Petteta, GR Dakwar, JB Van Den Dikkenberg, ...
Molecular pharmaceutics 12 (1), 150-161, 2015
272015
Mapping of the binding landscape for a picomolar protein-protein complex through computation and experiment
JS Yonatan Aizner, Oz Sharabi, Jason Shirian, George R. Dakwar, Marina ...
Structure 22 (4), 636-645, 2014
222014
PEGylated and functionalized aliphatic polycarbonate polyplex nanoparticles for intravenous administration of HDAC5 siRNA in cancer therapy
A Frère, A Baroni, E Hendrick, AS Delvigne, F Orange, O Peulen, ...
ACS Applied Materials & Interfaces 9 (3), 2181-2195, 2017
202017
Post-PEGylated and crosslinked polymeric ssRNA nanocomplexes as adjuvants targeting lymph nodes with increased cytolytic T cell inducing properties
B Lou, A De Beuckelaer, GR Dakwar, K Remaut, J Grooten, ...
Journal of controlled release 284, 73-83, 2018
172018
Effect of native gastric mucus on in vivo hybridization therapies directed at Helicobacter pylori
RS Santos, GR Dakwar, R Xiong, K Forier, K Remaut, S Stremersch, ...
Molecular Therapy-Nucleic Acids 4, 2015
152015
Exploring the HYDRAtion method for loading siRNA on liposomes: The interplay between stability and biological activity in human undiluted ascites fluid
GR Dakwar, K Braeckmans, W Ceelen, SC De Smedt, K Remaut
Drug delivery and translational research 7, 241-251, 2017
112017
Toxicity assessment of extracts from infusion sets in cEND brain endothelial cells
GR Dakwar, V Kaplun, L Kojukarov, P Gorenbein, I Schumacher, ...
International journal of pharmaceutics 434 (1-2), 20-27, 2012
72012
In Vitro Evaluation of Anti‐Aggregation and Degradation Behavior of PEGylated Polymeric Nanogels under In Vivo Like Conditions
Y Chen, GR Dakwar, K Braeckmans, T Lammers, WE Hennink, ...
Macromolecular bioscience 18 (1), 1700127, 2018
42018
Intraperitoneal nonviral nucleic acid delivery in the treatment of peritoneal cancer
G Dakwar, S De Smedt, K Remaut
Intraperitoneal Cancer Therapy: Principles and Practice, 359–371, 2015
42015
NANOPARTCLES’INCUBATION IN FETAL BOVINE SERUM IS NOT REPRESENTATIVE FOR PROTEIN CORONA FORMATION IN UNDILUTED BIOLOGICAL FLUIDS
GR Dakwar, A Ghazaryan, K Braeckmans, W Ceelen, V Mailänder
Exploring the intraperitoneal route of administration for siRNA delivery in …, 2016
2016
El sistema no puede realizar la operación en estos momentos. Inténtalo de nuevo más tarde.
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