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Mirit Aladjem
Mirit Aladjem
NCI
Dirección de correo verificada de mail.nih.gov
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The systems biology graphical notation
NL Novère, M Hucka, H Mi, S Moodie, F Schreiber, A Sorokin, E Demir, ...
Nature biotechnology 27 (8), 735-741, 2009
10482009
The BioPAX community standard for pathway data sharing
E Demir, MP Cary, S Paley, K Fukuda, C Lemer, I Vastrik, G Wu, ...
Nature biotechnology 28 (9), 935-942, 2010
7822010
The BioPAX community standard for pathway data sharing
E Demir, MP Cary, S Paley, K Fukuda, C Lemer, I Vastrik, G Wu, ...
Nature biotechnology 28 (9), 935-942, 2010
7732010
Phosphorylation of histone H2AX and activation of Mre11, Rad50, and Nbs1 in response to replication-dependent DNA double-strand breaks induced by mammalian DNA topoisomerase I …
T Furuta, H Takemura, ZY Liao, GJ Aune, C Redon, OA Sedelnikova, ...
Journal of Biological Chemistry 278 (22), 20303-20312, 2003
5692003
ES cells do not activate p53-dependent stress responses and undergo p53-independent apoptosis in response to DNA damage
MI Aladjem, BT Spike, LW Rodewald, TJ Hope, M Klemm, R Jaenisch, ...
Current Biology 8 (3), 145-155, 1998
5421998
Participation of the human β-globin locus control region in initiation of DNA replication
MI Aladjem, M Groudine, LL Brody, ES Dieken, REK Fournier, GM Wahl, ...
Science 270 (5237), 815-819, 1995
2901995
Genetic dissection of a mammalian replicator in the human β-globin locus
MI Aladjem, LW Rodewald, JL Kolman, GM Wahl
Science 281 (5379), 1005-1009, 1998
2651998
The intra-S-phase checkpoint affects both DNA replication initiation and elongation: single-cell and-DNA fiber analyses
JA Seiler, C Conti, A Syed, MI Aladjem, Y Pommier
Molecular and cellular biology 27 (16), 5806-5818, 2007
2442007
Replication in context: dynamic regulation of DNA replication patterns in metazoans
MI Aladjem
Nature Reviews Genetics 8 (8), 588-600, 2007
2432007
SLFN11 blocks stressed replication forks independently of ATR
J Murai, SW Tang, E Leo, SA Baechler, CE Redon, H Zhang, M Al Abo, ...
Molecular cell 69 (3), 371-384. e6, 2018
2042018
Dual roles of poly (dA: dT) tracts in replication initiation and fork collapse
A Tubbs, S Sridharan, N van Wietmarschen, Y Maman, E Callen, ...
Cell 174 (5), 1127-1142. e19, 2018
1822018
Mus81-mediated DNA cleavage resolves replication forks stalled by topoisomerase I–DNA complexes
M Regairaz, YW Zhang, H Fu, KK Agama, N Tata, S Agrawal, MI Aladjem, ...
Journal of Cell Biology 195 (5), 739-749, 2011
1742011
Molecular interaction maps of bioregulatory networks: a general rubric for systems biology
KW Kohn, MI Aladjem, JN Weinstein, Y Pommier
Molecular biology of the cell 17 (1), 1-13, 2006
1672006
Inhibition of histone deacetylase in cancer cells slows down replication forks, activates dormant origins, and induces DNA damage
C Conti, E Leo, GS Eichler, O Sordet, MM Martin, A Fan, MI Aladjem, ...
Cancer research 70 (11), 4470-4480, 2010
1592010
Phase I study of ATR inhibitor M6620 in combination with topotecan in patients with advanced solid tumors
A Thomas, CE Redon, L Sciuto, E Padiernos, J Ji, MJ Lee, A Yuno, S Lee, ...
Journal of Clinical Oncology 36 (16), 1594, 2018
1472018
Genome-wide depletion of replication initiation events in highly transcribed regions
MM Martin, M Ryan, RG Kim, AL Zakas, H Fu, CM Lin, WC Reinhold, ...
Genome research 21 (11), 1822-1832, 2011
1422011
ATAD5 regulates the lifespan of DNA replication factories by modulating PCNA level on the chromatin
K Lee, H Fu, MI Aladjem, K Myung
Journal of Cell Biology 200 (1), 31-44, 2013
1252013
Therapeutic targeting of ATR yields durable regressions in small cell lung cancers with high replication stress
A Thomas, N Takahashi, VN Rajapakse, X Zhang, Y Sun, M Ceribelli, ...
Cancer Cell 39 (4), 566-579. e7, 2021
1222021
Methylation of histone H3 on lysine 79 associates with a group of replication origins and helps limit DNA replication once per cell cycle
H Fu, AK Maunakea, MM Martin, L Huang, Y Zhang, M Ryan, RG Kim, ...
PLoS genetics 9 (6), e1003542, 2013
1192013
CellMiner Cross-Database (CellMinerCDB) version 1.2: Exploration of patient-derived cancer cell line pharmacogenomics
A Luna, F Elloumi, S Varma, Y Wang, VN Rajapakse, MI Aladjem, ...
Nucleic acids research 49 (D1), D1083-D1093, 2021
1162021
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Artículos 1–20