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Artak Tovmasyan
Artak Tovmasyan
Senior Research Associate, Duke University
Verified email at duke.edu
Title
Cited by
Cited by
Year
Manganese superoxide dismutase, MnSOD and its mimics
S Miriyala, I Spasojevic, A Tovmasyan, D Salvemini, Z Vujaskovic, ...
Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1822 (5), 794-814, 2012
4322012
SOD therapeutics: latest insights into their structure-activity relationships and impact on the cellular redox-based signaling pathways
I Batinic-Haberle, A Tovmasyan, ERH Roberts, Z Vujaskovic, KW Leong, ...
Antioxidants & redox signaling 20 (15), 2372-2415, 2014
2392014
An educational overview of the chemistry, biochemistry and therapeutic aspects of Mn porphyrins–from superoxide dismutation to H2O2-driven pathways
I Batinic-Haberle, A Tovmasyan, I Spasojevic
Redox biology 5, 43-65, 2015
1592015
Diverse functions of cationic Mn(III) N-substituted pyridylporphyrins, recognized as SOD mimics
I Batinic-Haberle, Z Rajic, A Tovmasyan, JS Reboucas, X Ye, KW Leong, ...
Free Radical Biology and Medicine 51 (5), 1035-1053, 2011
1542011
Mn porphyrin-based redox-active drugs: differential effects as cancer therapeutics and protectors of normal tissue against oxidative injury
I Batinic-Haberle, A Tovmasyan, I Spasojevic
Antioxidants & redox signaling 29 (16), 1691-1724, 2018
1192018
Design of Mn porphyrins for treating oxidative stress injuries and their redox-based regulation of cellular transcriptional activities
I Batinic-Haberle, I Spasojevic, HM Tse, A Tovmasyan, Z Rajic, ...
Amino acids 42, 95-113, 2012
1192012
Effect of molecular characteristics on cellular uptake, subcellular localization, and phototoxicity of Zn (II) N-alkylpyridylporphyrins
R Ezzeddine, A Al-Banaw, A Tovmasyan, JD Craik, I Batinic-Haberle, ...
Journal of Biological Chemistry 288 (51), 36579-36588, 2013
992013
Design, mechanism of action, bioavailability and therapeutic effects of mn porphyrin-based redox modulators
A Tovmasyan, H Sheng, T Weitner, A Arulpragasam, M Lu, DS Warner, ...
Medical Principles and Practice 22 (2), 103-130, 2013
972013
A new SOD mimic, Mn (III) ortho N-butoxyethylpyridylporphyrin, combines superb potency and lipophilicity with low toxicity
Z Rajic, A Tovmasyan, I Spasojevic, H Sheng, M Lu, AM Li, EB Gralla, ...
Free Radical Biology and Medicine 52 (9), 1828-1834, 2012
912012
A comprehensive evaluation of catalase-like activity of different classes of redox-active therapeutics
A Tovmasyan, CGC Maia, T Weitner, S Carballal, RS Sampaio, D Lieb, ...
Free Radical Biology and Medicine 86, 308-321, 2015
882015
Mn porphyrin in combination with ascorbate acts as a pro-oxidant and mediates caspase-independent cancer cell death
MK Evans, A Tovmasyan, I Batinic-Haberle, GR Devi
Free Radical Biology and Medicine 68, 302-314, 2014
822014
Novel manganese-porphyrin superoxide dismutase-mimetic widens the therapeutic margin in a preclinical head and neck cancer model
KA Ashcraft, MK Boss, A Tovmasyan, KR Choudhury, AN Fontanella, ...
International Journal of Radiation Oncology* Biology* Physics 93 (4), 892-900, 2015
802015
Anticancer therapeutic potential of Mn porphyrin/ascorbate system
A Tovmasyan, RS Sampaio, MK Boss, JC Bueno-Janice, BH Bader, ...
Free Radical Biology and Medicine 89, 1231-1247, 2015
742015
Differential coordination demands in Fe versus Mn water-soluble cationic metalloporphyrins translate into remarkably different aqueous redox chemistry and biology
A Tovmasyan, T Weitner, H Sheng, MM Lu, Z Rajic, DS Warner, ...
Inorganic chemistry 52 (10), 5677-5691, 2013
742013
Radioprotection of the Brain White Matter by Mn(III) N-Butoxyethylpyridylporphyrin–Based Superoxide Dismutase Mimic MnTnBuOE-2-PyP5+
DH Weitzel, A Tovmasyan, KA Ashcraft, Z Rajic, T Weitner, C Liu, W Li, ...
Molecular cancer therapeutics 14 (1), 70-79, 2015
732015
Simple biological systems for assessing the activity of superoxide dismutase mimics
A Tovmasyan, JS Reboucas, L Benov
Antioxidants & Redox Signaling 20 (15), 2416-2436, 2014
672014
Important cellular targets for antimicrobial photodynamic therapy
MM Awad, A Tovmasyan, JD Craik, I Batinic-Haberle, LT Benov
Applied microbiology and biotechnology 100, 7679-7688, 2016
642016
Comprehensive pharmacokinetic studies and oral bioavailability of two Mn porphyrin-based SOD mimics, MnTE-2-PyP5+ and MnTnHex-2-PyP5+
T Weitner, I Kos, H Sheng, A Tovmasyan, JS Reboucas, P Fan, ...
Free Radical Biology and Medicine 58, 73-80, 2013
612013
Cytotoxic effects of Mn (III) N-alkylpyridylporphyrins in the presence of cellular reductant, ascorbate
X Ye, D Fels, A Tovmasyan, KM Aird, C Dedeugd, JL Allensworth, I Kos, ...
Free radical research 45 (11-12), 1289-1306, 2011
592011
Optimizing Zn porphyrin-based photosensitizers for efficient antibacterial photodynamic therapy
K Alenezi, A Tovmasyan, I Batinic-Haberle, LT Benov
Photodiagnosis and photodynamic therapy 17, 154-159, 2017
532017
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