Hepatocyte nuclear factor 1 inactivation results in hepatic dysfunction, phenylketonuria, and renal Fanconi syndrome M Pontoglio, J Barra, M Hadchouel, A Doyen, C Kress, JP Bach, ... Cell 84 (4), 575-585, 1996 | 680 | 1996 |
Defective planar cell polarity in polycystic kidney disease E Fischer, E Legue, A Doyen, F Nato, JF Nicolas, V Torres, M Yaniv, ... Nature genetics 38 (1), 21-23, 2006 | 583 | 2006 |
Loss of Fat4 disrupts PCP signaling and oriented cell division and leads to cystic kidney disease S Saburi, I Hester, E Fischer, M Pontoglio, V Eremina, M Gessler, ... Nature genetics 40 (8), 1010-1015, 2008 | 543 | 2008 |
Hepatic stem-like phenotype and interplay of Wnt/β-catenin and Myc signaling in aggressive childhood liver cancer S Cairo, C Armengol, A De Reyniès, Y Wei, E Thomas, CA Renard, ... Cancer cell 14 (6), 471-484, 2008 | 463 | 2008 |
Defective insulin secretion in hepatocyte nuclear factor 1alpha-deficient mice. M Pontoglio, S Sreenan, M Roe, W Pugh, D Ostrega, A Doyen, AJ Pick, ... The Journal of clinical investigation 101 (10), 2215-2222, 1998 | 398 | 1998 |
Bile system morphogenesis defects and liver dysfunction upon targeted deletion of HNF1β C Coffinier, L Gresh, L Fiette, F Tronche, G Schütz, C Babinet, ... Oxford University Press for The Company of Biologists Limited 129 (8), 1829-1838, 2002 | 367 | 2002 |
A transcriptional network in polycystic kidney disease L Gresh, E Fischer, A Reimann, M Tanguy, S Garbay, X Shao, ... The EMBO journal 23 (7), 1657-1668, 2004 | 356 | 2004 |
Loss of HNF-1α function in mice leads to abnormal expression of genes involved in pancreatic islet development and metabolism DQ Shih, S Screenan, KN Munoz, L Philipson, M Pontoglio, M Yaniv, ... Diabetes 50 (11), 2472-2480, 2001 | 278 | 2001 |
HNF1α controls renal glucose reabsorption in mouse and man M Pontoglio, D Prié, C Cheret, A Doyen, C Leroy, P Froguel, G Velho, ... EMBO reports 1 (4), 359-365, 2000 | 266 | 2000 |
Analysis of the distribution of binding sites for a tissue-specific transcription factor in the vertebrate genome F Tronche, F Ringeisen, M Blumenfeld, M Yaniv, M Pontoglio Journal of molecular biology 266 (2), 231-245, 1997 | 224 | 1997 |
AKT2 is essential to maintain podocyte viability and function during chronic kidney disease G Canaud, F Bienaimé, A Viau, C Treins, W Baron, C Nguyen, M Burtin, ... Nature medicine 19 (10), 1288-1296, 2013 | 220 | 2013 |
Defective pancreatic β-cell glycolytic signaling in hepatocyte nuclear factor-1α-deficient mice ID Dukes, S Sreenan, MW Roe, M Levisetti, YP Zhou, D Ostrega, GI Bell, ... Journal of Biological Chemistry 273 (38), 24457-24464, 1998 | 212 | 1998 |
Characterization of the human OATP-C (SLC21A6) gene promoter and regulation of liver-specific OATP genes by hepatocyte nuclear factor 1α D Jung, B Hagenbuch, L Gresh, M Pontoglio, PJ Meier, GA Kullak-Ublick Journal of biological chemistry 276 (40), 37206-37214, 2001 | 184 | 2001 |
miR-17∼ 92 miRNA cluster promotes kidney cyst growth in polycystic kidney disease V Patel, D Williams, S Hajarnis, R Hunter, M Pontoglio, S Somlo, ... Proceedings of the National Academy of Sciences 110 (26), 10765-10770, 2013 | 166 | 2013 |
A mitotic transcriptional switch in polycystic kidney disease F Verdeguer, S Le Corre, E Fischer, C Callens, S Garbay, A Doyen, ... Nature medicine 16 (1), 106-110, 2010 | 153 | 2010 |
Transcription factor-dependent regulation of CBP and P/CAF histone acetyltransferase activity E Soutoglou, B Viollet, M Vaxillaire, M Yaniv, M Pontoglio, I Talianidis The EMBO journal 20 (8), 1984-1992, 2001 | 153 | 2001 |
PPARγ contributes to PKM2 and HK2 expression in fatty liver G Panasyuk, C Espeillac, C Chauvin, LA Pradelli, Y Horie, A Suzuki, ... Nature communications 3 (1), 672, 2012 | 147 | 2012 |
Hepatocyte nuclear factor 1, a transcription factor at the crossroads of glucose homeostasis M PONTOGLIO Journal of the American Society of Nephrology 11 (suppl 2), S140-S143, 2000 | 143 | 2000 |
Polycystin-2 and phosphodiesterase 4C are components of a ciliary A-kinase anchoring protein complex that is disrupted in cystic kidney diseases YH Choi, A Suzuki, S Hajarnis, Z Ma, HC Chapin, MJ Caplan, M Pontoglio, ... Proceedings of the National Academy of Sciences 108 (26), 10679-10684, 2011 | 137 | 2011 |
A genomic map of p53 binding sites identifies novel p53 targets involved in an apoptotic network C Miled, M Pontoglio, S Garbay, M Yaniv, JB Weitzman Cancer research 65 (12), 5096-5104, 2005 | 129 | 2005 |