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Guillermo Guenechea
Guillermo Guenechea
CIEMAT/CIBERER/IIS-FJD
Dirección de correo verificada de ciemat.es
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Disease-corrected haematopoietic progenitors from Fanconi anaemia induced pluripotent stem cells
Á Raya, I Rodríguez-Pizà, G Guenechea, R Vassena, S Navarro, ...
Nature 460 (7251), 53-59, 2009
9542009
Distinct classes of human stem cells that differ in proliferative and self-renewal potential
G Guenechea, OI Gan, C Dorrell, JE Dick
Nature immunology 2 (1), 75-82, 2001
3932001
CD34+AC133+ Cells Isolated from Cord Blood are Highly Enriched in Long-Term Culture-Initiating Cells, NOD/SCID-Repopulating Cells and Dendritic Cell …
EA De Wynter, D Buck, C Hart, R Heywood, LH Coutinho, A Clayton, ...
Stem Cells 16 (6), 387-396, 1998
3261998
Transduction of human CD34+ CD38-bone marrow and cord blood-derived SCID-repopulating cells with third-generation lentiviral vectors
G Guenechea, OI Gan, T Inamitsu, C Dorrell, DS Pereira, M Kelly, ...
Molecular Therapy 1 (6), 566-573, 2000
2202000
Delayed Engraftment of Nonobese Diabetic/Severe Combined Immunodeficient Mice Transplanted With Ex Vivo–Expanded Human CD34+ Cord Blood Cells
G Guenechea, JC Segovia, B Albella, M Lamana, M Ramırez, C Regidor, ...
Blood, The Journal of the American Society of Hematology 93 (3), 1097-1105, 1999
1791999
Successful engraftment of gene-corrected hematopoietic stem cells in non-conditioned patients with Fanconi anemia
P Rio, S Navarro, W Wang, R Sanchez-Dominguez, RM Pujol, ...
Nature medicine 25 (9), 1396-1401, 2019
1402019
Efficient transduction of human hematopoietic repopulating cells generating stable engraftment of transgene-expressing cells in NOD/SCID mice
J Barquinero, JC Segovia, M Ramırez, A Limón, G Güenechea, T Puig, ...
Blood, The Journal of the American Society of Hematology 95 (10), 3085-3093, 2000
772000
Lentiviral-mediated genetic correction of hematopoietic and mesenchymal progenitor cells from Fanconi anemia patients
A Jacome, S Navarro, P Río, RM Yañez, A González-Murillo, ML Lozano, ...
Molecular Therapy 17 (6), 1083-1092, 2009
712009
Efficient non-viral gene delivery into human hematopoietic stem cells by minicircle sleeping beauty transposon vectors
M Holstein, C Mesa-Nuñez, C Miskey, E Almarza, V Poletti, M Schmeer, ...
Molecular therapy 26 (4), 1137-1153, 2018
672018
A protocol describing the genetic correction of somatic human cells and subsequent generation of iPS cells
Á Raya, I Rodríguez-Pizà, S Navarro, Y Richaud-Patin, G Guenechea, ...
nature protocols 5 (4), 647-660, 2010
662010
Development of lentiviral vectors with optimized transcriptional activity for the gene therapy of patients with Fanconi anemia
A Gonzalez-Murillo, ML Lozano, L Alvarez, A Jacome, E Almarza, ...
Human gene therapy 21 (5), 623-630, 2010
622010
Engraftment and in vivo proliferation advantage of gene-corrected mobilized CD34+ cells from Fanconi anemia patients
P Río, S Navarro, G Guenechea, R Sánchez-Domínguez, ML Lamana, ...
Blood, The Journal of the American Society of Hematology 130 (13), 1535-1542, 2017
562017
Conversion of human fibroblasts into monocyte-like progenitor cells
J Pulecio, E Nivet, I Sancho-Martinez, M Vitaloni, G Guenechea, Y Xia, ...
Stem Cells 32 (11), 2923-2938, 2014
552014
Lentiviral vector integration sites in human NOD/SCID repopulating cells
S Laufs, G Guenechea, A Gonzalez‐Murillo, K Zsuzsanna Nagy, ...
The Journal of Gene Medicine: A cross‐disciplinary journal for research on …, 2006
482006
In vivo proliferation advantage of genetically corrected hematopoietic stem cells in a mouse model of Fanconi anemia FA-D1
P Río, NW Meza, Á González-Murillo, S Navarro, L Álvarez, J Surrallés, ...
Blood, The Journal of the American Society of Hematology 112 (13), 4853-4861, 2008
422008
Ex vivo expansion of umbilical cord blood (UCB) CD34+ cells alters the expression and function of α4β1 and α5β1 integrins
M Ramírez, JC Segovia, I Benet, C Arbona, G Güenechea, C Blaya, ...
British journal of haematology 115 (1), 213-221, 2001
402001
Generation of a high number of healthy erythroid cells from gene-edited pyruvate kinase deficiency patient-specific induced pluripotent stem cells
Z Garate, O Quintana-Bustamante, AM Crane, E Olivier, L Poirot, ...
Stem Cell Reports 5 (6), 1053-1066, 2015
392015
Characteristics of lentiviral vectors harboring the proximal promoter of the vav proto-oncogene: a weak and efficient promoter for gene therapy
E Almarza, P Río, NW Meza, M Aldea, X Agirre, G Guenechea, ...
Molecular Therapy 15 (8), 1487-1494, 2007
372007
In Vivo Dynamics of Human Stem Cell Repopulation in NOD/SCID Mice
JE Dick, G Guenechea, OI Gan, C Dorrell
Annals of the New York Academy of Sciences 938 (1), 184-190, 2001
352001
DNA delivery to ‘ex vivo’human liver segments
MJ Herrero, L Sabater, G Guenechea, L Sendra, AI Montilla, R Abargues, ...
Gene therapy 19 (5), 504-512, 2012
332012
El sistema no puede realizar la operación en estos momentos. Inténtalo de nuevo más tarde.
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