Christoph Lange
Christoph Lange
Biostatistics Department, Harvard School of Public Health
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A common genetic variant is associated with adult and childhood obesity
A Herbert, NP Gerry, MB McQueen, IM Heid, A Pfeufer, T Illig, ...
Science 312 (5771), 279-283, 2006
Family-based designs in the age of large-scale gene-association studies
NM Laird, C Lange
Nature Reviews Genetics 7 (5), 385-394, 2006
Genome-wide association analysis reveals putative Alzheimer's disease susceptibility loci in addition to APOE
L Bertram, C Lange, K Mullin, M Parkinson, M Hsiao, MF Hogan, ...
The American Journal of Human Genetics 83 (5), 623-632, 2008
Genome‐wide association scan of quantitative traits for attention deficit hyperactivity disorder identifies novel associations and confirms candidate gene associations
J Lasky‐Su, BM Neale, B Franke, RJL Anney, K Zhou, JB Maller, ...
American Journal of Medical Genetics Part B: Neuropsychiatric Genetics 147 …, 2008
Variants in FAM13A are associated with chronic obstructive pulmonary disease
MH Cho, N Boutaoui, BJ Klanderman, JS Sylvia, JP Ziniti, CP Hersh, ...
Nature genetics 42 (3), 200-202, 2010
Genomewide association between GLCCI1 and response to glucocorticoid therapy in asthma
KG Tantisira, J Lasky-Su, M Harada, A Murphy, AA Litonjua, BE Himes, ...
New England Journal of Medicine 365 (13), 1173-1183, 2011
MMP12, lung function, and COPD in high-risk populations
GM Hunninghake, MH Cho, Y Tesfaigzi, ME Soto-Quiros, L Avila, ...
New England Journal of Medicine 361 (27), 2599-2608, 2009
Genome-wide association analysis identifies PDE4D as an asthma-susceptibility gene
BE Himes, GM Hunninghake, JW Baurley, NM Rafaels, P Sleiman, ...
The American Journal of Human Genetics 84 (5), 581-593, 2009
Association of vitamin D receptor gene polymorphisms with childhood and adult asthma
BA Raby, R Lazarus, EK Silverman, S Lake, C Lange, M Wjst, ST Weiss
American journal of respiratory and critical care medicine 170 (10), 1057-1065, 2004
Genome‐wide association scan of attention deficit hyperactivity disorder
BM Neale, J Lasky‐Su, R Anney, B Franke, K Zhou, JB Maller, ...
American Journal of Medical Genetics Part B: Neuropsychiatric Genetics 147 …, 2008
Genome-wide meta-analyses of nonsyndromic cleft lip with or without cleft palate identify six new risk loci
KU Ludwig, E Mangold, S Herms, S Nowak, H Reutter, A Paul, J Becker, ...
Nature genetics 44 (9), 968-971, 2012
The transforming growth factor-β1 (TGFB1) gene is associated with chronic obstructive pulmonary disease (COPD)
JC Celedon, C Lange, BA Raby, AA Litonjua, LJ Palmer, DL DeMeo, ...
Human molecular genetics 13 (15), 1649-1656, 2004
PBAT: tools for family-based association studies
C Lange, D DeMeo, EK Silverman, ST Weiss, NM Laird
The American Journal of Human Genetics 74 (2), 367-369, 2004
Combined analysis from eleven linkage studies of bipolar disorder provides strong evidence of susceptibility loci on chromosomes 6q and 8q
MB McQueen, B Devlin, SV Faraone, VL Nimgaonkar, P Sklar, ...
The American Journal of Human Genetics 77 (4), 582-595, 2005
Genetic model testing and statistical power in population‐based association studies of quantitative traits
G Lettre, C Lange, JN Hirschhorn
Genetic Epidemiology: The Official Publication of the International Genetic …, 2007
Risk loci for chronic obstructive pulmonary disease: a genome-wide association study and meta-analysis
MH Cho, MLN McDonald, X Zhou, M Mattheisen, PJ Castaldi, CP Hersh, ...
The lancet Respiratory medicine 2 (3), 214-225, 2014
Family-based association between Alzheimer's disease and variants in UBQLN1
L Bertram, M Hiltunen, M Parkinson, M Ingelsson, C Lange, K Ramasamy, ...
New England Journal of Medicine 352 (9), 884-894, 2005
Genome-wide association study in obsessive-compulsive disorder: results from the OCGAS
M Mattheisen, JF Samuels, Y Wang, BD Greenberg, AJ Fyer, ...
Molecular psychiatry 20 (3), 337-344, 2015
A genome-wide association study of COPD identifies a susceptibility locus on chromosome 19q13
MH Cho, PJ Castaldi, ES Wan, M Siedlinski, CP Hersh, DL Demeo, ...
Human molecular genetics 21 (4), 947-957, 2012
Genetic association analysis of copy-number variation (CNV) in human disease pathogenesis
I Ionita-Laza, AJ Rogers, C Lange, BA Raby, C Lee
Genomics 93 (1), 22-26, 2009
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Artículos 1–20