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Linghang Peng
Linghang Peng
Verified email at scripps.edu
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Year
Isolation of potent SARS-CoV-2 neutralizing antibodies and protection from disease in a small animal model
TF Rogers, F Zhao, D Huang, N Beutler, A Burns, W He, O Limbo, C Smith, ...
Science 369 (6506), 956-963, 2020
13402020
Structural and functional ramifications of antigenic drift in recent SARS-CoV-2 variants
M Yuan, D Huang, CCD Lee, NC Wu, AM Jackson, X Zhu, H Liu, L Peng, ...
Science 373 (6556), 818-823, 2021
3472021
Broad and potent activity against SARS-like viruses by an engineered human monoclonal antibody
CG Rappazzo, LV Tse, CI Kaku, D Wrapp, M Sakharkar, D Huang, ...
Science 371 (6531), 823-829, 2021
2962021
Cross-reactive serum and memory B-cell responses to spike protein in SARS-CoV-2 and endemic coronavirus infection
G Song, W He, S Callaghan, F Anzanello, D Huang, J Ricketts, JL Torres, ...
Nature communications 12 (1), 2938, 2021
2722021
S-glycosylation-based cysteine profiling reveals regulation of glycolysis by itaconate
W Qin, KE Qin, Y Zhang, W Jia, Y Chen, BO Cheng, L Peng, N Chen, ...
Nature chemical biology 15 (10), 983-991, 2019
2132019
Artificial cysteine S‐glycosylation induced by per‐O‐acetylated unnatural monosaccharides during metabolic glycan labeling
W Qin, K Qin, X Fan, L Peng, W Hong, Y Zhu, P Lv, Y Du, R Huang, M Han, ...
Angewandte Chemie 130 (7), 1835-1838, 2018
1632018
A human antibody reveals a conserved site on beta-coronavirus spike proteins and confers protection against SARS-CoV-2 infection
P Zhou, M Yuan, G Song, N Beutler, N Shaabani, D Huang, W He, X Zhu, ...
Science translational medicine 14 (637), eabi9215, 2022
161*2022
Broadly neutralizing antibodies target the coronavirus fusion peptide
C Dacon, C Tucker, L Peng, CCD Lee, TH Lin, M Yuan, Y Cong, L Wang, ...
Science 377 (6607), 728-735, 2022
1332022
Bispecific antibodies targeting distinct regions of the spike protein potently neutralize SARS-CoV-2 variants of concern
H Cho, KK Gonzales-Wartz, D Huang, M Yuan, M Peterson, J Liang, ...
Science translational medicine 13 (616), eabj5413, 2021
92*2021
Broadly neutralizing anti-S2 antibodies protect against all three human betacoronaviruses that cause deadly disease
P Zhou, G Song, H Liu, M Yuan, W He, N Beutler, X Zhu, VT Longping, ...
Immunity 56 (3), 669-686. e7, 2023
68*2023
A natural mutation between SARS-CoV-2 and SARS-CoV determines neutralization by a cross-reactive antibody
NC Wu, M Yuan, S Bangaru, D Huang, X Zhu, CCD Lee, HL Turner, ...
PLoS pathogens 16 (12), e1009089, 2020
652020
A combination of cross-neutralizing antibodies synergizes to prevent SARS-CoV-2 and SARS-CoV pseudovirus infection
H Liu, M Yuan, D Huang, S Bangaru, F Zhao, CCD Lee, L Peng, ...
Cell host & microbe 29 (5), 806-818. e6, 2021
512021
A broad and potent neutralization epitope in SARS-related coronaviruses
M Yuan, X Zhu, W He, P Zhou, CI Kaku, T Capozzola, CY Zhu, X Yu, H Liu, ...
Proceedings of the National Academy of Sciences 119 (29), e2205784119, 2022
422022
One-shot identification of SARS-CoV-2 S RBD escape mutants using yeast screening
IM Francino-Urdaniz, PJ Steiner, MB Kirby, F Zhao, CM Haas, S Barman, ...
Cell Reports 36 (9), 2021
392021
Rare, convergent antibodies targeting the stem helix broadly neutralize diverse betacoronaviruses
C Dacon, L Peng, TH Lin, C Tucker, CCD Lee, Y Cong, L Wang, L Purser, ...
Cell host & microbe 31 (1), 97-111. e12, 2023
252023
A pandemic-enabled comparison of discovery platforms demonstrates a naïve antibody library can match the best immune-sourced antibodies
F Ferrara, MF Erasmus, S D’Angelo, C Leal-Lopes, AA Teixeira, ...
Nature communications 13 (1), 462, 2022
252022
Broadly neutralizing antibodies to SARS-related viruses can be readily induced in rhesus macaques
W He, M Yuan, S Callaghan, R Musharrafieh, G Song, M Silva, N Beutler, ...
Science translational medicine 14 (657), eabl9605, 2022
242022
Broadening a SARS-CoV-1–neutralizing antibody for potent SARS-CoV-2 neutralization through directed evolution
F Zhao, M Yuan, C Keating, N Shaabani, O Limbo, C Joyce, J Woehl, ...
Science Signaling 16 (798), eabk3516, 2023
92023
Engineering SARS-CoV-2 neutralizing antibodies for increased potency and reduced viral escape pathways
F Zhao, C Keating, G Ozorowski, N Shaabani, IM Francino-Urdaniz, ...
Iscience 25 (9), 2022
62022
A rapid assay for SARS-CoV-2 neutralizing antibodies that is insensitive to antiretroviral drugs
D Huang, JT Tran, L Peng, L Yang, RT Suhandynata, MA Hoffman, ...
The Journal of Immunology 207 (1), 344-351, 2021
52021
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