| Innate immune sensing of cytosolic chromatin fragments through cGAS promotes senescence S Glück, B Guey, MF Gulen, K Wolter, TW Kang, NA Schmacke, ... Nature cell biology 19 (9), 1061-1070, 2017 | 898 | 2017 |
| Targeting STING with covalent small-molecule inhibitors SM Haag, MF *Gulen, L Reymond, A Gibelin, L Abrami, A Decout, ... Nature 559 (7713), 269-273, 2018 | 704 | 2018 |
| Interleukin-23-independent IL-17 production regulates intestinal epithelial permeability JS Lee, CM Tato, B Joyce-Shaikh, MF Gulen, C Cayatte, Y Chen, ... Immunity 43 (4), 727-738, 2015 | 684 | 2015 |
| The adaptor Act1 is required for interleukin 17–dependent signaling associated with autoimmune and inflammatory disease Y Qian, C Liu, J Hartupee, CZ Altuntas, MF Gulen, D Jane-Wit, J Xiao, ... Nature immunology 8 (3), 247-256, 2007 | 662 | 2007 |
| Mycobacterium tuberculosis differentially activates cGAS-and inflammasome-dependent intracellular immune responses through ESX-1 R Wassermann, MF *Gulen, C Sala, SG Perin, Y Lou, J Rybniker, ... Cell host & microbe 17 (6), 799-810, 2015 | 388 | 2015 |
| Signalling strength determines proapoptotic functions of STING MF Gulen, U Koch, SM Haag, F Schuler, L Apetoh, A Villunger, F Radtke, ... Nature communications 8 (1), 427, 2017 | 373 | 2017 |
| The Toll–interleukin-1 receptor member SIGIRR regulates colonic epithelial homeostasis, inflammation, and tumorigenesis H Xiao, MF *Gulen, J Qin, J Yao, K Bulek, D Kish, CZ Altuntas, D Wald, ... Immunity 26 (4), 461-475, 2007 | 372 | 2007 |
| Astrocyte-restricted ablation of interleukin-17-induced Act1-mediated signaling ameliorates autoimmune encephalomyelitis Z Kang, CZ Altuntas, MF Gulen, C Liu, N Giltiay, H Qin, L Liu, W Qian, ... Immunity 32 (3), 414-425, 2010 | 328 | 2010 |
| The cGAS–STING pathway drives type I IFN immunopathology in COVID-19 JD Domizio, MF *Gulen, F Saidoune, VV Thacker, A Yatim, K Sharma, ... Nature 603 (7899), 145-151, 2022 | 320 | 2022 |
| The receptor SIGIRR suppresses Th17 cell proliferation via inhibition of the interleukin-1 receptor pathway and mTOR kinase activation MF Gulen, Z Kang, K Bulek, W Youzhong, TW Kim, Y Chen, CZ Altuntas, ... Immunity 32 (1), 54-66, 2010 | 227 | 2010 |
| The essential role of single Ig IL-1 receptor-related molecule/Toll IL-1R8 in regulation of Th2 immune response K Bulek, S Swaidani, J Qin, Y Lu, MF Gulen, T Herjan, B Min, ... The Journal of Immunology 182 (5), 2601-2609, 2009 | 221 | 2009 |
| The inducible kinase IKKi is required for IL-17-dependent signaling associated with neutrophilia and pulmonary inflammation K Bulek, C Liu, S Swaidani, L Wang, RC Page, MF Gulen, T Herjan, ... Nature immunology 12 (9), 844-852, 2011 | 216 | 2011 |
| T cell–intrinsic ASC critically promotes TH17-mediated experimental autoimmune encephalomyelitis BN Martin, C Wang, C Zhang, Z Kang, MF Gulen, JA Zepp, J Zhao, G Bian, ... Nature immunology 17 (5), 583-592, 2016 | 161 | 2016 |
| cGAS–STING drives ageing-related inflammation and neurodegeneration MF Gulen, N Samson, A Keller, M Schwabenland, C Liu, S Glück, ... Nature 620 (7973), 374-380, 2023 | 149 | 2023 |
| Interleukin-1 (IL-1)-induced TAK1-dependent versus MEKK3-dependent NFκB activation pathways bifurcate at IL-1 receptor-associated kinase modification J Yao, TW Kim, J Qin, Z Jiang, Y Qian, H Xiao, Y Lu, W Qian, MF Gulen, ... Journal of Biological Chemistry 282 (9), 6075-6089, 2007 | 131 | 2007 |
| IKKα negatively regulates ASC-dependent inflammasome activation BN Martin, C Wang, J Willette-Brown, T Herjan, MF Gulen, H Zhou, ... Nature communications 5 (1), 4977, 2014 | 118 | 2014 |
| SIGIRR, a negative regulator of TLR/IL-1R signalling promotes Microbiota dependent resistance to colonization by enteric bacterial pathogens HP Sham, EYS Yu, MF Gulen, G Bhinder, M Stahl, JM Chan, L Brewster, ... PLoS pathogens 9 (8), e1003539, 2013 | 93 | 2013 |
| Inactivation of the enzyme GSK3α by the kinase IKKi promotes AKT-mTOR signaling pathway that mediates interleukin-1-induced Th17 cell maintenance MF Gulen, K Bulek, H Xiao, M Yu, J Gao, L Sun, E Beurel, ... Immunity 37 (5), 800-812, 2012 | 93 | 2012 |
| IL-17-induced Act1-mediated signaling is critical for cuprizone-induced demyelination Z Kang, L Liu, R Spangler, C Spear, C Wang, MF Gulen, M Veenstra, ... Journal of Neuroscience 32 (24), 8284-8292, 2012 | 93 | 2012 |
| Cutting edge: TNF receptor-associated factor 4 restricts IL-17–mediated pathology and signaling processes JA Zepp, C Liu, W Qian, L Wu, MF Gulen, Z Kang, X Li The Journal of Immunology 189 (1), 33-37, 2012 | 90 | 2012 |
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