| A new mouse model for the trisomy of the Abcg1–U2af1 region reveals the complexity of the combinatorial genetic code of down syndrome PL Pereira, L Magnol, I Sahun, V Brault, A Duchon, P Prandini, A Gruart, ... Human molecular genetics 18 (24), 4756-4769, 2009 | 131 | 2009 |
| Excitation/inhibition balance and learning are modified by Dyrk1a gene dosage B Souchet, F Guedj, I Sahún, A Duchon, F Daubigney, A Badel, ... Neurobiology of disease 69, 65-75, 2014 | 117 | 2014 |
| Overexpression of Reelin prevents the manifestation of behavioral phenotypes related to schizophrenia and bipolar disorder CM Teixeira, ED Martín, I Sahún, N Masachs, L Pujadas, A Corvelo, ... Neuropsychopharmacology 36 (12), 2395-2405, 2011 | 114 | 2011 |
| RESEARCH FOCUS ON COMPULSIVE BEHAVIOUR IN ANIMALS: An animal model of compulsive food‐taking behaviour A Heyne, C Kiesselbach, I Sahún, J McDonald, M Gaiffi, M Dierssen, ... Addiction biology 14 (4), 373-383, 2009 | 107 | 2009 |
| Motor phenotypic alterations in TgDyrk1a transgenic mice implicate DYRK1A in Down syndrome motor dysfunction MM de Lagrán, X Altafaj, X Gallego, E Martı, X Estivill, I Sahun, C Fillat, ... Neurobiology of disease 15 (1), 132-142, 2004 | 98 | 2004 |
| Ceramide levels regulated by carnitine palmitoyltransferase 1C control dendritic spine maturation and cognition P Carrasco, I Sahun, J McDonald, S Ramírez, J Jacas, E Gratacós, ... Journal of Biological Chemistry 287 (25), 21224-21232, 2012 | 89 | 2012 |
| Targeting Dyrk1A with AAVshRNA attenuates motor alterations in TgDyrk1A, a mouse model of Down syndrome J Ortiz-Abalia, I Sahún, X Altafaj, N Andreu, X Estivill, M Dierssen, C Fillat The American Journal of Human Genetics 83 (4), 479-488, 2008 | 85 | 2008 |
| Heterozygous deletion of the Williams–Beuren syndrome critical interval in mice recapitulates most features of the human disorder M Segura-Puimedon, I Sahún, E Velot, P Dubus, C Borralleras, ... Human molecular genetics 23 (24), 6481-6494, 2014 | 84 | 2014 |
| Transgenic mice overexpressing the full-length neurotrophin receptor TrkC exhibit increased catecholaminergic neuron density in specific brain areas and increased anxiety-like … M Dierssen, M Gratacòs, I Sahún, M Martín, X Gallego, A Amador-Arjona, ... Neurobiology of disease 24 (2), 403-418, 2006 | 62 | 2006 |
| Intracisternal Gtf2i gene therapy ameliorates deficits in cognition and synaptic plasticity of a mouse model of Williams–Beuren syndrome C Borralleras, I Sahun, LA Pérez-Jurado, V Campuzano Molecular Therapy 23 (11), 1691-1699, 2015 | 54 | 2015 |
| Dissociation between CA3–CA1 synaptic plasticity and associative learning in TgNTRK3 transgenic mice I Sahún, JM Delgado-García, A Amador-Arjona, A Giralt, J Alberch, ... Journal of Neuroscience 27 (9), 2253-2260, 2007 | 54 | 2007 |
| Mutations in L-type amino acid transporter-2 support SLC7A8 as a novel gene involved in age-related hearing loss M Espino Guarch, M Font-Llitjos, S Murillo-Cuesta, E Errasti-Murugarren, ... Elife 7, e31511, 2018 | 50 | 2018 |
| Carnitine palmitoyltransferase 1C deficiency causes motor impairment and hypoactivity P Carrasco, J Jacas, I Sahún, H Muley, S Ramírez, B Puisac, P Mezquita, ... Behavioural Brain Research 256, 291-297, 2013 | 43 | 2013 |
| Impaired development of neocortical circuits contributes to the neurological alterations in DYRK1A haploinsufficiency syndrome J Arranz, E Balducci, K Arató, G Sánchez-Elexpuru, S Najas, A Parras, ... Neurobiology of disease 127, 210-222, 2019 | 41 | 2019 |
| DREAM controls the on/off switch of specific activity-dependent transcription pathways B Mellström, I Sahún, A Ruiz-Nuño, P Murtra, R Gomez-Villafuertes, ... Molecular and cellular biology 34 (5), 877-887, 2014 | 41 | 2014 |
| Candidate genes for panic disorder: insight from human and mouse genetic studies M Gratacos, I Sahun, X Gallego, A Amador‐Arjona, X Estivill, M Dierssen Genes, Brain and Behavior 6, 2-23, 2007 | 41 | 2007 |
| Opposite Phenotypes of Muscle Strength and Locomotor Function in Mouse Models of Partial Trisomy and Monosomy 21 for the Proximal Hspa13-App Region V Brault, A Duchon, C Romestaing, I Sahun, S Pothion, M Karout, C Borel, ... PLoS genetics 11 (3), e1005062, 2015 | 39 | 2015 |
| Developmental molecular and functional cerebellar alterations induced by PCP4/PEP19 overexpression: implications for Down syndrome F Mouton-Liger, I Sahún, T Collin, PL Pereira, D Masini, S Thomas, E Paly, ... Neurobiology of Disease 63, 92-106, 2014 | 23 | 2014 |
| Cognition and hippocampal plasticity in the mouse is altered by monosomy of a genomic region implicated in Down syndrome I Sahún, D Marechal, PL Pereira, V Nalesso, A Gruart, JMD Garcia, ... Genetics 197 (3), 899-912, 2014 | 19 | 2014 |
| AGC 1‐malate aspartate shuttle activity is critical for dopamine handling in the nigrostriatal pathway I Llorente‐Folch, I Sahún, L Contreras, MJ Casarejos, JM Grau, T Saheki, ... Journal of neurochemistry 124 (3), 347-362, 2013 | 19 | 2013 |
