| Lysophosphatidylcholine regulates sexual stage differentiation in the human malaria parasite Plasmodium falciparum NMB Brancucci, JP Gerdt, CQ Wang, M De Niz, N Philip, SR Adapa, ... Cell 171 (7), 1532-1544. e15, 2017 | 299 | 2017 |
| Cancer-derived exosomes loaded with ultrathin palladium nanosheets for targeted bioorthogonal catalysis M Sancho-Albero, B Rubio-Ruiz, AM Pérez-López, V Sebastián, ... Nature catalysis 2 (10), 864-872, 2019 | 230 | 2019 |
| Gold‐triggered uncaging chemistry in living systems AM Pérez‐López, B Rubio‐Ruiz, V Sebastián, L Hamilton, C Adam, ... Angewandte Chemie International Edition 56 (41), 12548-12552, 2017 | 156 | 2017 |
| Efficient palladium-triggered release of vorinostat from a bioorthogonal precursor B Rubio-Ruiz, JT Weiss, A Unciti-Broceta Journal of Medicinal Chemistry 59 (21), 9974-9980, 2016 | 112 | 2016 |
| Bright insights into palladium-triggered local chemotherapy TL Bray, M Salji, A Brombin, AM Pérez-López, B Rubio-Ruiz, ... Chemical Science 9 (37), 7354-7361, 2018 | 86 | 2018 |
| Bioorthogonal uncaging of the active metabolite of irinotecan by palladium‐functionalized microdevices C Adam, AM Pérez‐López, L Hamilton, B Rubio‐Ruiz, TL Bray, D Sieger, ... Chemistry–A European Journal 24 (63), 16783-16790, 2018 | 57 | 2018 |
| The mechanism of allosteric coupling in choline kinase α1 revealed by the action of a rationally designed inhibitor M Sahún‐Roncero, B Rubio‐Ruiz, G Saladino, A Conejo‐García, ... Angewandte Chemie International Edition 52 (17), 4582-4586, 2013 | 47 | 2013 |
| Effects of indomethacin, nimesulide, and diclofenac on human MG-63 osteosarcoma cell line L Díaz-Rodríguez, O García-Martínez, MA Morales, L Rodríguez-Pérez, ... Biological research for nursing 14 (1), 98-107, 2012 | 46 | 2012 |
| Pharmaco-genomic investigations of organo-iridium anticancer complexes reveal novel mechanism of action JM Hearn, GM Hughes, I Romero-Canelón, AF Munro, B Rubio-Ruiz, ... Metallomics 10 (1), 93-107, 2018 | 42 | 2018 |
| Plasmodium falciparum Choline Kinase Inhibition Leads to a Major Decrease in Phosphatidylethanolamine Causing Parasite Death L Serrán-Aguilera, H Denton, B Rubio-Ruiz, B López-Gutiérrez, A Entrena, ... Scientific reports 6 (1), 33189, 2016 | 38 | 2016 |
| High-precision photothermal ablation using biocompatible palladium nanoparticles and laser scanning microscopy B Rubio-Ruiz, AM Pérez-López, TL Bray, M Lee, A Serrels, M Prieto, ... ACS applied materials & interfaces 10 (4), 3341-3348, 2018 | 37 | 2018 |
| Bioorthogonal uncaging of cytotoxic paclitaxel through Pd nanosheet–hydrogel frameworks AM Pérez-López, B Rubio-Ruiz, T Valero, R Contreras-Montoya, ... Journal of Medicinal Chemistry 63 (17), 9650-9659, 2020 | 36 | 2020 |
| N-alkynyl derivatives of 5-fluorouracil: susceptibility to palladium-mediated dealkylation and toxigenicity in cancer cell culture JT Weiss, C Fraser, B Rubio-Ruiz, SH Myers, R Crispin, JC Dawson, ... Frontiers in Chemistry 2, 56, 2014 | 35 | 2014 |
| Design, synthesis, theoretical calculations and biological evaluation of new non-symmetrical choline kinase inhibitors B Rubio-Ruíz, A Conejo-García, P Ríos-Marco, MP Carrasco-Jiménez, ... European journal of medicinal chemistry 50, 154-162, 2012 | 33 | 2012 |
| Discovery of a new binding site on human choline kinase α1: design, synthesis, crystallographic studies, and biological evaluation of asymmetrical bispyridinium derivatives B Rubio-Ruiz, A Figuerola-Conchas, J Ramos-Torrecillas, ... Journal of medicinal chemistry 57 (2), 507-515, 2014 | 29 | 2014 |
| Effect of acetaminophen (paracetamol) on human osteosarcoma cell line MG63 L Díaz-Rodríguez, O García-Martínez, M Arroyo-Morales, B Rubio-Ruiz, ... Acta Pharmacologica Sinica 31 (11), 1495-1499, 2010 | 27 | 2010 |
| Determination of potential scaffolds for human choline kinase α1 by chemical deconvolution studies M SAHUN RONCERO, B Rubio Ruíz, A Conejo García, ... ChemBioChem 14 (11), 1291-1295, 2013 | 25 | 2013 |
| A 5-FU Precursor Designed to Evade Anabolic and Catabolic Drug Pathways and Activated by Pd Chemistry In Vitro and In Vivo C Adam, TL Bray, AM Pérez-López, EH Tan, B Rubio-Ruiz, DJ Baillache, ... Journal of Medicinal Chemistry 65 (1), 552-561, 2022 | 24 | 2022 |
| Nondestructive production of exosomes loaded with ultrathin palladium nanosheets for targeted bio-orthogonal catalysis V Sebastian, M Sancho‐Albero, M Arruebo, AM Pérez‐López, ... Nature Protocols 16 (1), 131-163, 2021 | 22 | 2021 |
| Recent advances in the design of choline kinase α inhibitors and the molecular basis of their inhibition B Rubio‐Ruiz, L Serrán‐Aguilera, R Hurtado‐Guerrero, A Conejo‐García Medicinal Research Reviews 41 (2), 902-927, 2021 | 19 | 2021 |
Asier Unciti-BrocetaUniversity of EdinburghDirección de correo verificada de ed.ac.uk
