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Christopher Bolen
Christopher Bolen
Scientist, Genentech
Dirección de correo verificada de gene.com
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Non-equivalence of Wnt and R-spondin ligands during Lgr5+ intestinal stem-cell self-renewal
KS Yan, CY Janda, J Chang, GXY Zheng, KA Larkin, VC Luca, LA Chia, ...
Nature 545 (7653), 238-242, 2017
4022017
Expression of specific inflammasome gene modules stratifies older individuals into two extreme clinical and immunological states
D Furman, J Chang, L Lartigue, CR Bolen, F Haddad, B Gaudilliere, ...
Nature Medicine 23 (2), 174-184, 2017
3602017
Dynamic expression profiling of Type I and Type III Interferon‐stimulated hepatocytes reveals a stable hierarchy of gene expression
CR Bolen, S Ding, MD Robek, SH Kleinstein
Hepatology, 2013
2162013
Quantitative set analysis for gene expression: a method to quantify gene set differential expression including gene-gene correlations
G Yaari, CR Bolen, J Thakar, SH Kleinstein
Nucleic acids research 41 (18), e170-e170, 2013
2052013
Venetoclax plus rituximab in relapsed chronic lymphocytic leukemia: 4-year results and evaluation of impact of genomic complexity and gene mutations from the MURANO phase III study
AP Kater, JQ Wu, TJ Kipps, B Eichhorst, P Hillmen, J D’rozario, ...
Journal of Clinical Oncology 38 (34), 2020
1832020
Individual heritable differences result in unique cell lymphocyte receptor repertoires of naïve and antigen-experienced cells
F Rubelt, CR Bolen, HM McGuire, JA Vander Heiden, D Gadala-Maria, ...
Nature communications 7, 11112, 2016
1162016
Integration of cell of origin into the clinical CNS International Prognostic Index improves CNS relapse prediction in DLBCL
M Klanova, LH Sehn, I Bence-Bruckler, F Cavallo, J Jin, M Martelli, ...
Blood 133 (9), 919-926, 2019
1102019
Dysregulation of B Cell Repertoire Formation in Myasthenia Gravis Patients Revealed through Deep Sequencing
JA Vander Heiden, P Stathopoulos, JQ Zhou, L Chen, TJ Gilbert, ...
The Journal of Immunology 198 (4), 1460-1473, 2017
1102017
A randomized, open-label, Phase III study of obinutuzumab or rituximab plus CHOP in patients with previously untreated diffuse large B-Cell lymphoma: final analysis of GOYA
LH Sehn, M Martelli, M Trněný, W Liu, CR Bolen, A Knapp, D Sahin, ...
Journal of Hematology & Oncology 13, 1-9, 2020
1012020
Lambda and alpha interferons inhibit hepatitis B virus replication through a common molecular mechanism but with different in vivo activities
NE Pagliaccetti, EN Chu, CR Bolen, SH Kleinstein, MD Robek
Virology 401 (2), 197-206, 2010
952010
Multicenter Systems Analysis of Human Blood Reveals Immature Neutrophils in Males and During Pregnancy
J Blazkova, S Gupta, Y Liu, B Gaudilliere, EA Ganio, CR Bolen, ...
The Journal of Immunology 198 (6), 2479-2488, 2017
802017
Cell subset prediction for blood genomic studies
CR Bolen, M Uduman, SH Kleinstein
BMC bioinformatics 12 (1), 258, 2011
762011
Mass cytometry panel optimization through the designed distribution of signal interference
C Takahashi, A Au‐Yeung, F Fuh, T Ramirez‐Montagut, C Bolen, ...
Cytometry Part A 91 (1), 39-47, 2017
742017
Safety, Clinical Activity, and Biological Correlates of Response in Patients with Metastatic Melanoma: Results from a Phase I Trial of Atezolizumab
O Hamid, L Molinero, CR Bolen, JA Sosman, E Muñoz-Couselo, ...
Clinical Cancer Research 25 (20), 6061-6072, 2019
662019
PD-L1 and tumor-associated macrophages in de novo DLBCL
R McCord, CR Bolen, H Koeppen, EE Kadel III, MZ Oestergaard, ...
Blood advances 3 (4), 531-540, 2019
642019
Prognostic impact of natural killer cell count in follicular lymphoma and diffuse large B-cell lymphoma patients treated with immunochemotherapy
M Klanova, MZ Oestergaard, M Trněný, W Hiddemann, R Marcus, ...
Clinical Cancer Research 25 (15), 4634-4643, 2019
602019
Mass cytometry identifies a distinct monocyte cytokine signature shared by clinically heterogeneous pediatric SLE patients
WE O'Gorman, DS Kong, IM Balboni, P Rudra, CR Bolen, D Ghosh, ...
Journal of autoimmunity 81, 74-89, 2017
602017
Quantitative comparison of conventional and t-SNE-guided gating analyses
ST Eshghi, A Au-Yeung, C Takahashi, CR Bolen, MN Nyachienga, ...
Frontiers in immunology 10, 2019
562019
The Blood Transcriptional Signature of Chronic Hepatitis C Virus Is Consistent with an Ongoing Interferon-Mediated Antiviral Response
CR Bolen, MD Robek, L Brodsky, V Schulz, JK Lim, MW Taylor, ...
Journal of Interferon & Cytokine Research 33 (1), 15-23, 2013
502013
The Repertoire Dissimilarity Index as a method to compare lymphocyte receptor repertoires
CR Bolen, F Rubelt, JA Vander Heiden, MM Davis
BMC Bioinformatics 18 (1), 155, 2017
492017
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Artículos 1–20