| IDO1 in cancer: a Gemini of immune checkpoints L Zhai, E Ladomersky, A Lenzen, B Nguyen, R Patel, KL Lauing, M Wu, ... Cellular & molecular immunology 15 (5), 447-457, 2018 | 305 | 2018 |
| Molecular pathways: targeting IDO1 and other tryptophan dioxygenases for cancer immunotherapy L Zhai, S Spranger, DC Binder, G Gritsina, KL Lauing, FJ Giles, ... Clinical cancer research 21 (24), 5427-5433, 2015 | 289 | 2015 |
| IDO1 inhibition synergizes with radiation and PD-1 blockade to durably increase survival against advanced glioblastoma E Ladomersky, L Zhai, A Lenzen, KL Lauing, J Qian, DM Scholtens, ... Clinical cancer research 24 (11), 2559-2573, 2018 | 165 | 2018 |
| Infiltrating T cells increase IDO1 expression in glioblastoma and contribute to decreased patient survival L Zhai, E Ladomersky, KL Lauing, M Wu, M Genet, G Gritsina, B Győrffy, ... Clinical Cancer Research 23 (21), 6650-6660, 2017 | 146 | 2017 |
| Immunosuppressive IDO in cancer: Mechanisms of action, animal models, and targeting strategies L Zhai, A Bell, E Ladomersky, KL Lauing, L Bollu, JA Sosman, B Zhang, ... Frontiers in immunology 11, 1185, 2020 | 144 | 2020 |
| The coincidence between increasing age, immunosuppression, and the incidence of patients with glioblastoma E Ladomersky, DM Scholtens, M Kocherginsky, EA Hibler, ET Bartom, ... Frontiers in pharmacology 10, 200, 2019 | 112 | 2019 |
| Alcohol exposure and mechanisms of tissue injury and repair MK Jung, JJ Callaci, KL Lauing, JS Otis, KA Radek, MK Jones, EJ Kovacs Alcoholism: Clinical and Experimental Research 35 (3), 392-399, 2011 | 106 | 2011 |
| The role of IDO in brain tumor immunotherapy L Zhai, KL Lauing, AL Chang, M Dey, J Qian, Y Cheng, MS Lesniak, ... Journal of neuro-oncology 123 (3), 395-403, 2015 | 100 | 2015 |
| Aggrecan is required for growth plate cytoarchitecture and differentiation KL Lauing, M Cortes, MS Domowicz, JG Henry, AT Baria, NB Schwartz Developmental biology 396 (2), 224-236, 2014 | 97 | 2014 |
| Binge alcohol treatment of adolescent rats followed by alcohol abstinence is associated with site-specific differences in bone loss and incomplete recovery of bone mass and … K Lauing, R Himes, M Rachwalski, P Strotman, JJ Callaci Alcohol 42 (8), 649-656, 2008 | 83 | 2008 |
| Binge alcohol-induced bone damage is accompanied by differential expression of bone remodeling-related genes in rat vertebral bone JJ Callaci, R Himes, K Lauing, FH Wezeman, K Brownson Calcified tissue international 84 (6), 474-484, 2009 | 72 | 2009 |
| Advanced age increases immunosuppression in the brain and decreases immunotherapeutic efficacy in subjects with glioblastoma E Ladomersky, L Zhai, KL Lauing, A Bell, J Xu, M Kocherginsky, B Zhang, ... Clinical Cancer Research 26 (19), 5232-5245, 2020 | 69 | 2020 |
| The kynurenine to tryptophan ratio as a prognostic tool for glioblastoma patients enrolling in immunotherapy L Zhai, M Dey, KL Lauing, G Gritsina, R Kaur, RV Lukas, MK Nicholas, ... Journal of Clinical Neuroscience 22 (12), 1964-1968, 2015 | 67 | 2015 |
| Acute alcohol exposure impairs fracture healing and deregulates β‐catenin signaling in the fracture callus KL Lauing, PM Roper, RK Nauer, JJ Callaci Alcoholism: Clinical and Experimental Research 36 (12), 2095-2103, 2012 | 64 | 2012 |
| Mesenchymal stem cells facilitate fracture repair in an alcohol-induced impaired healing model T Obermeyer, D Yonick, K Lauing, S Stock, R Nauer, P Strotman, ... Journal of orthopaedic trauma 26 (12), 712, 2012 | 61 | 2012 |
| Tumor cell IDO enhances immune suppression and decreases survival independent of tryptophan metabolism in glioblastoma L Zhai, A Bell, E Ladomersky, KL Lauing, L Bollu, B Nguyen, M Genet, ... Clinical Cancer Research 27 (23), 6514-6528, 2021 | 60 | 2021 |
| Non-tumor cell IDO1 predominantly contributes to enzyme activity and response to CTLA-4/PD-L1 inhibition in mouse glioblastoma L Zhai, E Ladomersky, CR Dostal, KL Lauing, K Swoap, LK Billingham, ... Brain, behavior, and immunity 62, 24-29, 2017 | 54 | 2017 |
| Glioblastoma as an age-related neurological disorder in adults M Kim, E Ladomersky, A Mozny, M Kocherginsky, K O’Shea, ZZ Reinstein, ... Neuro-oncology advances 3 (1), vdab125, 2021 | 46 | 2021 |
| Exogenous activation of Wnt/β-catenin signaling attenuates binge alcohol-induced deficient bone fracture healing KL Lauing, S Sundaramurthy, RK Nauer, JJ Callaci Alcohol and alcoholism 49 (4), 399-408, 2014 | 40 | 2014 |
| Antioxidant therapy attenuates deficient bone fracture repair associated with binge alcohol exposure DL Volkmer, B Sears, KL Lauing, RK Nauer, PM Roper, S Yong, M Stover, ... Journal of orthopaedic trauma 25 (8), 516, 2011 | 34 | 2011 |
