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Sonsoles Velazquez
Sonsoles Velazquez
Investigador CSIC
Verified email at iqm.csic.es
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Year
1, 2, 3-Triazole-[2, 5-Bis-O-(tert-butyldimethylsilyl)-. beta.-D-ribofuranosyl]-3'-spiro-5''-(4''-amino-1'', 2''-oxathiole 2'', 2''-dioxide)(TSAO) Analogs: Synthesis and Anti …
R Alvarez, S Velazquez, A San-Felix, S Aquaro, ED Clercq, CF Perno, ...
Journal of medicinal chemistry 37 (24), 4185-4194, 1994
10181994
Regiospecific Synthesis and Anti-Human Immunodeficiency Virus Activity of Novel 5-Substituted N-Alkylcarbamoyl and N,N-Dialkyl Carbamoyl 1,2,3-Triazole …
S Velazquez, R Alvarez, C Perez, F Gago, E De Clercq, J Balzarini, ...
Antiviral Chemistry and Chemotherapy 9 (6), 481-489, 1998
2821998
Potent and selective inhibition of varicella-zoster virus (VZV) by nucleoside analogues with an unusual bicyclic base
C McGuigan, CJ Yarnold, G Jones, S Velázquez, H Barucki, A Brancale, ...
Journal of medicinal chemistry 42 (22), 4479-4484, 1999
2551999
Characterization of the activation pathway of phosphoramidate triester prodrugs of stavudine and zidovudine
D Saboulard, L Naesens, D Cahard, A Salgado, R Pathirana, ...
Molecular Pharmacology 56 (4), 693-704, 1999
1881999
Phosphoramidate derivatives of d4T as inhibitors of HIV: the effect of amino acid variation
C McGuigan, HW Tsang, D Cahard, K Turner, S Velazquez, A Salgado, ...
Antiviral research 35 (3), 195-204, 1997
1001997
Resistance of HIV-1 reverse transcriptase against [2', 5'-bis-O-(tert-butyldimethylsilyl)-3'-spiro-5 “-(4”-amino-1 “, 2”-oxathiole-2 “, 2”-dioxide)](TSAO) derivatives is …
H Jonckheere, JM Taymans, J Balzarini, S Velazquez, MJ Camarasa, ...
Journal of Biological Chemistry 269 (41), 25255-25258, 1994
991994
Preclinical development of bicyclic nucleoside analogues as potent and selective inhibitors of varicella zoster virus
C McGuigan, RN Pathirana, M Migliore, R Adak, G Luoni, AT Jones, ...
Journal of antimicrobial chemotherapy 60 (6), 1316-1330, 2007
932007
Dimerization inhibitors of HIV-1 reverse transcriptase, protease and integrase: a single mode of inhibition for the three HIV enzymes?
MJ Camarasa, S Velázquez, A San-Félix, MJ Pérez-Pérez, F Gago
Antiviral research 71 (2-3), 260-267, 2006
882006
Identification of a Putative Binding Site for [2‘,5‘-Bis-O-(tert-butyldimethylsilyl)-β-d-ribofuranosyl]-3‘-spiro-5‘ ‘-(4‘ ‘-amino-1‘ ‘,2‘ ‘-oxathiole-2‘ ‘,2‘ ‘-dioxide …
F Rodríguez-Barrios, C Pérez, E Lobatón, S Velázquez, C Chamorro, ...
Journal of Medicinal Chemistry 44 (12), 1853-1865, 2001
822001
Suppression of the breakthrough of human immunodeficiency virus type 1 (HIV-1) in cell culture by thiocarboxanilide derivatives when used individually or in combination with …
J Balzarini, MJ Perez-Perez, S Velazquez, A San-Felix, MJ Camarasa, ...
Proceedings of the National Academy of Sciences 92 (12), 5470-5474, 1995
731995
3′-spiro-5′′-(4′′-amino-1′′, 2′′-oxathiole-2′′, 2′′-dioxide)(TSAO) derivatives of purine and pyrimidine nucleosides as potent and selective inhibitors of human …
J Balzarini, MJ Pérez-Pérez, A San-Félix, S Velazquez, MJ Camarasa, ...
Antimicrob. Agents Chemother 36 (5), 1073-1080, 1992
691992
TSAO compounds: the comprehensive story of a unique family of HIV-1 specific inhibitors of reverse transcriptase
MJ Camarasa, A San-Félix, S Velázquez, MJ Pérez-Pérez, F Gago, ...
Current topics in medicinal chemistry 4 (9), 945-963, 2004
662004
Synthesis and anti-HIV activity of [AZT]-[TSAO-T] and [AZT]-[HEPT] dimers as potential multifunctional inhibitors of HIV-1 reverse transcriptase
S Velazquez, R Alvarez, A San-Felix, ML Jimeno, E De Clercq, J Balzarini, ...
Journal of medicinal chemistry 38 (10), 1641-1649, 1995
591995
Antivascular and antitumor properties of the tubulin-binding chalcone TUB091
MD Canela, S Noppen, O Bueno, AE Prota, K Bargsten, G Sáez-Calvo, ...
Oncotarget 8 (9), 14325, 2017
582017
Novel series of TSAO-T derivatives. Synthesis and anti-HIV-1 activity of 4-, 5-, and 6-substituted pyrimidine analogs
A San-Felix, S Velazquez, MJ Perez-Perez, J Balzarini, E De Clercq, ...
Journal of medicinal chemistry 37 (4), 453-460, 1994
551994
Human immunodeficiency virus type 1-specific [2', 5'-bis-O-(tert-butyldimethylsilyl)-beta-D-ribofuranosyl]-3'-spiro-5"-(4"-amino-1", 2"-oxathiole-2", 2"-dioxide)-purine …
J Balzarini, S Velazquez, A San-Felix, A Karlsson, MJ Perez-Perez, ...
Molecular pharmacology 43 (1), 109-114, 1993
501993
Fluorescent bicyclic furo pyrimidine deoxynucleoside analogs as potent and selective inhibitors of VZV and potential future drugs for the treatment of chickenpox and shingles
C McGuigan, A Brancale, H Barucki
Drugs of the Future 25 (11), 2000
452000
Potential multifunctional inhibitors of HIV-1 reverse transcriptase. Novel [AZT]-[TSAO-T] and [d4T]-[TSAO-T] heterodimers modified in the linker and in the dideoxynucleoside region
S Velázquez, V Tuñón, ML Jimeno, C Chamorro, E De Clercq, J Balzarini, ...
Journal of medicinal chemistry 42 (25), 5188-5196, 1999
451999
J. antiviral chemistry
S Velazquez, R Alvarez, C Perez, F Gago, C De, J Balzarini, M Camaraza
Chem. Chemother 9, 481, 1998
431998
TSAO analogs. 3. Synthesis and anti-HIV-1 activity of 2', 5'-bis-O-(tert-butyldimethylsilyl)-. beta.-D-ribofuranosyl 3'-spiro-5"-(4"-amino-1", 2"-oxathiole 2", 2"-dioxide …
S Velazquez, A San-Felix, MJ Perez-Perez, J Balzarini, E De Clercq, ...
Journal of medicinal chemistry 36 (22), 3230-3239, 1993
431993
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