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Martin Franz Orth
Martin Franz Orth
physician, MD PhD
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Cited by
Cited by
Year
Heterogeneity of neuroblastoma cell identity defined by transcriptional circuitries
V Boeva, C Louis-Brennetot, A Peltier, S Durand, C Pierre-Eugène, ...
Nature genetics 49 (9), 1408-1413, 2017
3962017
Evidence for an alternative fatty acid desaturation pathway increasing cancer plasticity
K Vriens, S Christen, S Parik, D Broekaert, K Yoshinaga, A Talebi, ...
Nature 566 (7744), 403-406, 2019
3582019
Proline metabolism supports metastasis formation and could be inhibited to selectively target metastasizing cancer cells
I Elia, D Broekaert, S Christen, R Boon, E Radaelli, MF Orth, C Verfaillie, ...
Nature communications 8 (1), 15267, 2017
3332017
Breast cancer-derived lung metastases show increased pyruvate carboxylase-dependent anaplerosis
S Christen, D Lorendeau, R Schmieder, D Broekaert, K Metzger, K Veys, ...
Cell reports 17 (3), 837-848, 2016
2262016
Eukaryotic initiation factor 4E-binding protein 1 (4E-BP1): a master regulator of mRNA translation involved in tumorigenesis
J Musa, MF Orth, M Dallmayer, M Baldauf, C Pardo, B Rotblat, T Kirchner, ...
Oncogene 35 (36), 4675-4688, 2016
1572016
PHGDH heterogeneity potentiates cancer cell dissemination and metastasis
M Rossi, P Altea-Manzano, M Demicco, G Doglioni, L Bornes, M Fukano, ...
Nature 605 (7911), 747-753, 2022
872022
An update on the LIM and SH3 domain protein 1 (LASP1): a versatile structural, signaling, and biomarker protein
MF Orth, A Cazes, E Butt, TGP Grunewald
Oncotarget 6 (1), 26, 2015
822015
Robust diagnosis of Ewing sarcoma by immunohistochemical detection of super-enhancer-driven EWSR1-ETS targets
MC Baldauf, MF Orth, M Dallmayer, A Marchetto, JS Gerke, RA Rubio, ...
Oncotarget 9 (2), 1587, 2018
802018
Loss of tumor suppressor mir-203 mediates overexpression of LIM and SH3 Protein 1 (LASP1) in high-risk prostate cancer thereby increasing cell proliferation and migration
A Hailer, TGP Grunewald, M Orth, C Reiss, B Kneitz, M Spahn, E Butt
Oncotarget 5 (12), 4144, 2014
742014
Cooperation of cancer drivers with regulatory germline variants shapes clinical outcomes
J Musa, F Cidre-Aranaz, MM Aynaud, MF Orth, MML Knott, O Mirabeau, ...
Nature communications 10 (1), 4128, 2019
582019
Regulation of matrix metalloproteinases (MMPs) expression and secretion in MDA-MB-231 breast cancer cells by LIM and SH3 protein 1 (LASP1)
M Endres, S Kneitz, MF Orth, RK Perera, A Zernecke, E Butt
Oncotarget 7 (39), 64244, 2016
552016
mTOR signaling and SREBP activity increase FADS2 expression and can activate sapienate biosynthesis
M Triki, G Rinaldi, M Planque, D Broekaert, AM Winkelkotte, CR Maier, ...
Cell reports 31 (12), 2020
482020
A comparative view on the expression patterns of PD-L1 and PD-1 in soft tissue sarcomas
MF Orth, VL Buecklein, E Kampmann, M Subklewe, E Noessner, ...
Cancer Immunology, Immunotherapy 69, 1353-1362, 2020
442020
Oncogenic hijacking of a developmental transcription factor evokes vulnerability toward oxidative stress in Ewing sarcoma
A Marchetto, S Ohmura, MF Orth, MML Knott, MV Colombo, C Arrigoni, ...
Nature communications 11 (1), 2423, 2020
402020
Gene expression and immunohistochemical analyses identify SOX2 as major risk factor for overall survival and relapse in Ewing sarcoma patients
G Sannino, A Marchetto, A Ranft, S Jabar, C Zacherl, R Alba-Rubio, ...
EBioMedicine 47, 156-162, 2019
282019
Translational evidence for RRM2 as a prognostic biomarker and therapeutic target in Ewing sarcoma
S Ohmura, A Marchetto, MF Orth, J Li, S Jabar, A Ranft, E Vinca, ...
Molecular Cancer 20, 1-7, 2021
262021
Targeting the CALCB/RAMP1 axis inhibits growth of Ewing sarcoma
M Dallmayer, J Li, S Ohmura, R Alba Rubio, MC Baldauf, TLB Hölting, ...
Cell death & disease 10 (2), 116, 2019
252019
Are EWSR1-NFATc2-positive sarcomas really Ewing sarcomas?
MC Baldauf, JS Gerke, MF Orth, M Dallmayer, D Baumhoer, E de Alava, ...
Modern Pathology 31 (6), 997-999, 2018
242018
Systematic identification of cancer-specific MHC-binding peptides with RAVEN
MC Baldauf, JS Gerke, A Kirschner, F Blaeschke, M Effenberger, ...
Oncoimmunology 7 (9), e1481558, 2018
222018
High specificity of BCL11B and GLG1 for EWSR1-FLI1 and EWSR1-ERG positive Ewing sarcoma
MF Orth, TLB Hölting, M Dallmayer, FS Wehweck, T Paul, J Musa, ...
Cancers 12 (3), 644, 2020
212020
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