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Yuan Wang
Yuan Wang
State Key Laboratory of Biotherapy, West China Hospital, Sichuan University
Dirección de correo verificada de scu.edu.cn
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Expression of mutant p53 proteins implicates a lineage relationship between neural stem cells and malignant astrocytic glioma in a murine model
Y Wang, J Yang, H Zheng, GJ Tomasek, P Zhang, PE McKeever, ...
Cancer cell 15 (6), 514-526, 2009
3132009
ERK inhibition rescues defects in fate specification of Nf1-deficient neural progenitors and brain abnormalities
Y Wang, E Kim, X Wang, BG Novitch, K Yoshikawa, LS Chang, Y Zhu
Cell 150 (4), 816-830, 2012
1412012
Sequential fate-switches in stem-like cells drive the tumorigenic trajectory from human neural stem cells to malignant glioma
X Wang, R Zhou, Y Xiong, L Zhou, X Yan, M Wang, F Li, C Xie, Y Zhang, ...
Cell Research 31 (6), 684-702, 2021
522021
KMT2C deficiency promotes small cell lung cancer metastasis through DNMT3A-mediated epigenetic reprogramming
F Na, X Pan, J Chen, X Chen, M Wang, P Chi, L You, L Zhang, A Zhong, ...
Nature cancer 3 (6), 753-767, 2022
462022
A reignited debate over the cell (s) of origin for glioblastoma and its clinical implications
X Fan, Y Xiong, Y Wang
Frontiers of Medicine 13, 531-539, 2019
382019
Transient inhibition of the ERK pathway prevents cerebellar developmental defects and improves long-term motor functions in murine models of neurofibromatosis type 1
E Kim, Y Wang, SJ Kim, M Bornhorst, ES Jecrois, TE Anthony, C Wang, ...
Elife 3, e05151, 2014
322014
Plasma cells shape the mesenchymal identity of ovarian cancers through transfer of exosome-derived microRNAs
Z Yang, W Wang, L Zhao, X Wang, RC Gimple, L Xu, Y Wang, JN Rich, ...
Science Advances 7 (9), eabb0737, 2021
312021
Spatial transcriptomics reveals niche-specific enrichment and vulnerabilities of radial glial stem-like cells in malignant gliomas
Y Ren, Z Huang, L Zhou, P Xiao, J Song, P He, C Xie, R Zhou, M Li, ...
Nature Communications 14 (1), 1028, 2023
272023
Integrated single-cell RNA sequencing analysis reveals distinct cellular and transcriptional modules associated with survival in lung cancer
L Zhang, Y Zhang, C Wang, Y Yang, Y Ni, Z Wang, T Song, M Yao, Z Liu, ...
Signal Transduction and Targeted Therapy 7 (1), 9, 2022
272022
Structural and mechanistic insights into secretagogin-mediated exocytosis
J Qin, Q Liu, Z Liu, YZ Pan, L Sifuentes-Dominguez, KP Stepien, Y Wang, ...
Proceedings of the National Academy of Sciences 117 (12), 6559-6570, 2020
262020
Acquired semi-squamatization during chemotherapy suggests differentiation as a therapeutic strategy for bladder cancer
M Wang, X Chen, P Tan, Y Wang, X Pan, T Lin, Y Jiang, B Wang, H Xu, ...
Cancer Cell 40 (9), 1044-1059. e8, 2022
252022
Opposing tumor-promoting and-suppressive functions of rictor/mTORC2 signaling in adult glioma and pediatric SHH medulloblastoma
S Akgül, Y Li, S Zheng, M Kool, DM Treisman, C Li, Y Wang, S Gröbner, ...
Cell reports 24 (2), 463-478. e5, 2018
252018
PtdIns4P restriction by hydrolase SAC1 decides specific fusion of autophagosomes with lysosomes
H Zhang, J Zhou, P Xiao, Y Lin, X Gong, S Liu, Q Xu, M Wang, H Ren, ...
Autophagy 17 (8), 1907-1917, 2021
232021
Murine models of IDH-wild-type glioblastoma exhibit spatial segregation of tumor initiation and manifestation during evolution
Y Li, B Li, W Li, Y Wang, S Akgül, DM Treisman, KA Heist, BR Pierce, ...
Nature communications 11 (1), 3669, 2020
192020
Treatment during a developmental window prevents NF1-associated optic pathway gliomas by targeting Erk-dependent migrating glial progenitors
ES Jecrois, W Zheng, M Bornhorst, Y Li, DM Treisman, D Muguyo, ...
Developmental Cell 56 (20), 2871-2885. e6, 2021
172021
An Epigenetic Mechanism Underlying Chromosome 17p Deletion–Driven Tumorigenesis
M Chen, X Chen, S Li, X Pan, Y Gong, J Zheng, J Xu, C Zhao, Q Zhang, ...
Cancer discovery 11 (1), 194-207, 2021
142021
Crosstalk between m6A regulators and mRNA during cancer progression
X Niu, Y Yang, Y Ren, S Zhou, Q Mao, Y Wang
Oncogene 41 (39), 4407-4419, 2022
112022
Spatial transcriptomics in development and disease
R Zhou, G Yang, Y Zhang, Y Wang
Molecular Biomedicine 4 (1), 32, 2023
52023
Sashimi. py: a flexible toolkit for combinatorial analysis of genomic data
Y Zhang, R Zhou, Y Wang
bioRxiv, 2022.11. 02.514803, 2022
52022
Cryo-EM structure of the Mon1–Ccz1–RMC1 complex reveals molecular basis of metazoan RAB7A activation
X Yong, G Jia, Z Liu, C Zhou, J Yi, Y Tang, L Chen, L Chen, Y Wang, ...
Proceedings of the National Academy of Sciences 120 (22), e2301725120, 2023
42023
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