Smad3 mutant mice develop metastatic colorectal cancer Y Zhu, JA Richardson, LF Parada, JM Graff Cell 94 (6), 703-714, 1998 | 842 | 1998 |
Neurofibromas in NF1: Schwann cell origin and role of tumor environment Y Zhu, P Ghosh, P Charnay, DK Burns, LF Parada Science 296 (5569), 920-922, 2002 | 740 | 2002 |
Ablation of NF1 function in neurons induces abnormal development of cerebral cortex and reactive gliosis in the brain Y Zhu, MI Romero, P Ghosh, Z Ye, P Charnay, EJ Rushing, JD Marth, ... Genes & development 15 (7), 859-876, 2001 | 682 | 2001 |
Early inactivation of p53 tumor suppressor gene cooperating with NF1 loss induces malignant astrocytoma Y Zhu, F Guignard, D Zhao, L Liu, DK Burns, RP Mason, A Messing, ... Cancer cell 8 (2), 119-130, 2005 | 620 | 2005 |
Neurofibromin regulation of ERK signaling modulates GABA release and learning Y Cui, RM Costa, GG Murphy, Y Elgersma, Y Zhu, DH Gutmann, ... Cell 135 (3), 549-560, 2008 | 454 | 2008 |
The molecular and genetic basis of neurological tumours Y Zhu, LF Parada Nature Reviews Cancer 2 (8), 616-626, 2002 | 415 | 2002 |
Nf1-dependent tumors require a microenvironment containing Nf1+/−-and c-kit-dependent bone marrow FC Yang, DA Ingram, S Chen, Y Zhu, J Yuan, X Li, X Yang, S Knowles, ... Cell 135 (3), 437-448, 2008 | 402 | 2008 |
Astrocyte-Specific Inactivation of the Neurofibromatosis 1 Gene (NF1) Is Insufficient for Astrocytoma Formation ML Bajenaru, Y Zhu, NM Hedrick, J Donahoe, LF Parada, DH Gutmann Molecular and cellular biology 22 (14), 5100-5113, 2002 | 334 | 2002 |
Optic nerve glioma in mice requires astrocyte Nf1 gene inactivation and Nf1 brain heterozygosity ML Bajenaru, MR Hernandez, A Perry, Y Zhu, LF Parada, JR Garbow, ... Cancer research 63 (24), 8573-8577, 2003 | 316 | 2003 |
Expression of mutant p53 proteins implicates a lineage relationship between neural stem cells and malignant astrocytic glioma in a murine model Y Wang, J Yang, H Zheng, GJ Tomasek, P Zhang, PE McKeever, ... Cancer cell 15 (6), 514-526, 2009 | 313 | 2009 |
Somatic inactivation of Nf1 in hematopoietic cells results in a progressive myeloproliferative disorder DT Le, N Kong, Y Zhu, JO Lauchle, A Aiyigari, BS Braun, E Wang, ... Blood 103 (11), 4243-4250, 2004 | 205 | 2004 |
Inactivation of NF1 in CNS causes increased glial progenitor proliferation and optic glioma formation Y Zhu, T Harada, L Liu, ME Lush, F Guignard, C Harada, DK Burns, ... Oxford University Press for The Company of Biologists Limited 132 (24), 5577 …, 2005 | 199 | 2005 |
Nf1 has an essential role in endothelial cells AD Gitler, Y Zhu, FA Ismat, MM Lu, Y Yamauchi, LF Parada, JA Epstein Nature genetics 33 (1), 75-79, 2003 | 198 | 2003 |
Induction of abnormal proliferation by nonmyelinating schwann cells triggers neurofibroma formation H Zheng, L Chang, N Patel, J Yang, L Lowe, DK Burns, Y Zhu Cancer cell 13 (2), 117-128, 2008 | 190 | 2008 |
The loss of Nf1 transiently promotes self-renewal but not tumorigenesis by neural crest stem cells NM Joseph, JT Mosher, J Buchstaller, P Snider, PE McKeever, M Lim, ... Cancer cell 13 (2), 129-140, 2008 | 173 | 2008 |
FIP200 is required for maintenance and differentiation of postnatal neural stem cells C Wang, CC Liang, ZC Bian, Y Zhu, JL Guan Nature neuroscience 16 (5), 532-542, 2013 | 162 | 2013 |
Pediatric low-grade gliomas: implications of the biologic era RJ Packer, S Pfister, E Bouffet, R Avery, P Bandopadhayay, M Bornhorst, ... Neuro-oncology 19 (6), 750-761, 2017 | 156 | 2017 |
Pediatric low-grade gliomas: next biologically driven steps DTW Jones, MW Kieran, E Bouffet, S Alexandrescu, P Bandopadhayay, ... Neuro-oncology 20 (2), 160-173, 2018 | 147 | 2018 |
ERK inhibition rescues defects in fate specification of Nf1-deficient neural progenitors and brain abnormalities Y Wang, E Kim, X Wang, BG Novitch, K Yoshikawa, LS Chang, Y Zhu Cell 150 (4), 816-830, 2012 | 142 | 2012 |
A network of heterochronic genes including Imp1 regulates temporal changes in stem cell properties J Nishino, S Kim, Y Zhu, H Zhu, SJ Morrison elife 2, e00924, 2013 | 128 | 2013 |