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Yuan Zhu
Yuan Zhu
Children's National Hospital
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Smad3 mutant mice develop metastatic colorectal cancer
Y Zhu, JA Richardson, LF Parada, JM Graff
Cell 94 (6), 703-714, 1998
8421998
Neurofibromas in NF1: Schwann cell origin and role of tumor environment
Y Zhu, P Ghosh, P Charnay, DK Burns, LF Parada
Science 296 (5569), 920-922, 2002
7402002
Ablation of NF1 function in neurons induces abnormal development of cerebral cortex and reactive gliosis in the brain
Y Zhu, MI Romero, P Ghosh, Z Ye, P Charnay, EJ Rushing, JD Marth, ...
Genes & development 15 (7), 859-876, 2001
6822001
Early inactivation of p53 tumor suppressor gene cooperating with NF1 loss induces malignant astrocytoma
Y Zhu, F Guignard, D Zhao, L Liu, DK Burns, RP Mason, A Messing, ...
Cancer cell 8 (2), 119-130, 2005
6202005
Neurofibromin regulation of ERK signaling modulates GABA release and learning
Y Cui, RM Costa, GG Murphy, Y Elgersma, Y Zhu, DH Gutmann, ...
Cell 135 (3), 549-560, 2008
4542008
The molecular and genetic basis of neurological tumours
Y Zhu, LF Parada
Nature Reviews Cancer 2 (8), 616-626, 2002
4152002
Nf1-dependent tumors require a microenvironment containing Nf1+/−-and c-kit-dependent bone marrow
FC Yang, DA Ingram, S Chen, Y Zhu, J Yuan, X Li, X Yang, S Knowles, ...
Cell 135 (3), 437-448, 2008
4022008
Astrocyte-Specific Inactivation of the Neurofibromatosis 1 Gene (NF1) Is Insufficient for Astrocytoma Formation
ML Bajenaru, Y Zhu, NM Hedrick, J Donahoe, LF Parada, DH Gutmann
Molecular and cellular biology 22 (14), 5100-5113, 2002
3342002
Optic nerve glioma in mice requires astrocyte Nf1 gene inactivation and Nf1 brain heterozygosity
ML Bajenaru, MR Hernandez, A Perry, Y Zhu, LF Parada, JR Garbow, ...
Cancer research 63 (24), 8573-8577, 2003
3162003
Expression of mutant p53 proteins implicates a lineage relationship between neural stem cells and malignant astrocytic glioma in a murine model
Y Wang, J Yang, H Zheng, GJ Tomasek, P Zhang, PE McKeever, ...
Cancer cell 15 (6), 514-526, 2009
3132009
Somatic inactivation of Nf1 in hematopoietic cells results in a progressive myeloproliferative disorder
DT Le, N Kong, Y Zhu, JO Lauchle, A Aiyigari, BS Braun, E Wang, ...
Blood 103 (11), 4243-4250, 2004
2052004
Inactivation of NF1 in CNS causes increased glial progenitor proliferation and optic glioma formation
Y Zhu, T Harada, L Liu, ME Lush, F Guignard, C Harada, DK Burns, ...
Oxford University Press for The Company of Biologists Limited 132 (24), 5577 …, 2005
1992005
Nf1 has an essential role in endothelial cells
AD Gitler, Y Zhu, FA Ismat, MM Lu, Y Yamauchi, LF Parada, JA Epstein
Nature genetics 33 (1), 75-79, 2003
1982003
Induction of abnormal proliferation by nonmyelinating schwann cells triggers neurofibroma formation
H Zheng, L Chang, N Patel, J Yang, L Lowe, DK Burns, Y Zhu
Cancer cell 13 (2), 117-128, 2008
1902008
The loss of Nf1 transiently promotes self-renewal but not tumorigenesis by neural crest stem cells
NM Joseph, JT Mosher, J Buchstaller, P Snider, PE McKeever, M Lim, ...
Cancer cell 13 (2), 129-140, 2008
1732008
FIP200 is required for maintenance and differentiation of postnatal neural stem cells
C Wang, CC Liang, ZC Bian, Y Zhu, JL Guan
Nature neuroscience 16 (5), 532-542, 2013
1622013
Pediatric low-grade gliomas: implications of the biologic era
RJ Packer, S Pfister, E Bouffet, R Avery, P Bandopadhayay, M Bornhorst, ...
Neuro-oncology 19 (6), 750-761, 2017
1562017
Pediatric low-grade gliomas: next biologically driven steps
DTW Jones, MW Kieran, E Bouffet, S Alexandrescu, P Bandopadhayay, ...
Neuro-oncology 20 (2), 160-173, 2018
1472018
ERK inhibition rescues defects in fate specification of Nf1-deficient neural progenitors and brain abnormalities
Y Wang, E Kim, X Wang, BG Novitch, K Yoshikawa, LS Chang, Y Zhu
Cell 150 (4), 816-830, 2012
1422012
A network of heterochronic genes including Imp1 regulates temporal changes in stem cell properties
J Nishino, S Kim, Y Zhu, H Zhu, SJ Morrison
elife 2, e00924, 2013
1282013
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Artículos 1–20