| Human C3 mutation reveals a mechanism of dense deposit disease pathogenesis and provides insights into complement activation and regulation R Martínez-Barricarte, M Heurich, F Valdes-Cañedo, E Vazquez-Martul, ... The Journal of clinical investigation 120 (10), 3702-3712, 2010 | 258 | 2010 |
| C3 glomerulopathy–associated CFHR1 mutation alters FHR oligomerization and complement regulation A Tortajada, H Yébenes, C Abarrategui-Garrido, J Anter, ... The Journal of clinical investigation 123 (6), 2434-2446, 2013 | 207 | 2013 |
| Factor H-related proteins determine complement-activating surfaces M Józsi, A Tortajada, B Uzonyi, EG de Jorge, SR de Córdoba Trends in immunology 36 (6), 374-384, 2015 | 162 | 2015 |
| The disease-protective complement factor H allotypic variant Ile62 shows increased binding affinity for C3b and enhanced cofactor activity A Tortajada, T Montes, R Martı́nez-Barricarte, BP Morgan, CL Harris, ... Human molecular genetics 18 (18), 3452-3461, 2009 | 150 | 2009 |
| Genetics of atypical hemolytic uremic syndrome (aHUS) SR de Cordoba, MS Hidalgo, S Pinto, A Tortajada Seminars in thrombosis and hemostasis, 422-430, 2014 | 149 | 2014 |
| Functional basis of protection against age-related macular degeneration conferred by a common polymorphism in complement factor B T Montes, A Tortajada, BP Morgan, S Rodríguez de Córdoba, CL Harris Proceedings of the National Academy of Sciences 106 (11), 4366-4371, 2009 | 145 | 2009 |
| Complement dysregulation and disease: from genes and proteins to diagnostics and drugs SR de Cordoba, A Tortajada, CL Harris, BP Morgan Immunobiology 217 (11), 1034-1046, 2012 | 143 | 2012 |
| A novel atypical hemolytic uremic syndrome–associated hybrid CFHR1/CFH gene encoding a fusion protein that antagonizes factor H–dependent complement regulation E Valoti, M Alberti, A Tortajada, J Garcia-Fernandez, S Gastoldi, L Besso, ... Journal of the American Society of Nephrology 26 (1), 209-219, 2015 | 123 | 2015 |
| The role of complement in IgA nephropathy A Tortajada, E Gutierrez, MC Pickering, MP Terente, N Medjeral-Thomas Molecular immunology 114, 123-132, 2019 | 113 | 2019 |
| Measurement of factor H variants in plasma using variant-specific monoclonal antibodies: application to assessing risk of age-related macular degeneration S Hakobyan, CL Harris, A Tortajada, EG De Jorge, A Garcia-Layana, ... Investigative ophthalmology & visual science 49 (5), 1983-1990, 2008 | 108 | 2008 |
| Elevated factor H–related protein 1 and factor H pathogenic variants decrease complement regulation in IgA nephropathy A Tortajada, E Gutiérrez, EG de Jorge, J Anter, A Segarra, M Espinosa, ... Kidney international 92 (4), 953-963, 2017 | 107 | 2017 |
| 3D structure of the C3bB complex provides insights into the activation and regulation of the complement alternative pathway convertase E Torreira, A Tortajada, T Montes, SR de Córdoba, O Llorca Proceedings of the National Academy of Sciences 106 (3), 882-887, 2009 | 99 | 2009 |
| Structural basis for the stabilization of the complement alternative pathway C3 convertase by properdin M Alcorlo, A Tortajada, S Rodríguez de Córdoba, O Llorca Proceedings of the National Academy of Sciences 110 (33), 13504-13509, 2013 | 96 | 2013 |
| Atypical hemolytic uremic syndrome-associated variants and autoantibodies impair binding of factor h and factor h-related protein 1 to pentraxin 3 A Kopp, S Strobel, A Tortajada, S Rodriguez de Cordoba, ... The Journal of Immunology 189 (4), 1858-1867, 2012 | 68 | 2012 |
| Complete functional characterization of disease-associated genetic variants in the complement factor H gene HM Merinero, SP García, J García-Fernández, E Arjona, A Tortajada, ... Kidney international 93 (2), 470-481, 2018 | 61 | 2018 |
| The molecular and structural bases for the association of complement C3 mutations with atypical hemolytic uremic syndrome R Martínez-Barricarte, M Heurich, A López-Perrote, A Tortajada, S Pinto, ... Molecular immunology 66 (2), 263-273, 2015 | 60 | 2015 |
| Variant-specific quantification of factor H in plasma identifies null alleles associated with atypical hemolytic uremic syndrome S Hakobyan, A Tortajada, CL Harris, SR De Córdoba, BP Morgan Kidney international 78 (8), 782-788, 2010 | 59 | 2010 |
| Interaction between multimeric von Willebrand factor and complement: a fresh look to the pathophysiology of microvascular thrombosis S Bettoni, M Galbusera, S Gastoldi, R Donadelli, C Tentori, G Spartà, ... The Journal of Immunology 199 (3), 1021-1040, 2017 | 57 | 2017 |
| FHR-1 binds to C-reactive protein and enhances rather than inhibits complement activation AI Csincsi, Z Szabó, Z Bánlaki, B Uzonyi, M Cserhalmi, E Karpati, ... The Journal of Immunology 199 (1), 292-303, 2017 | 54 | 2017 |
| Familial C3 glomerulonephritis caused by a novel CFHR5-CFHR2 fusion gene X Xiao, C Ghossein, A Tortajada, Y Zhang, N Meyer, M Jones, NG Borsa, ... Molecular immunology 77, 89-96, 2016 | 53 | 2016 |
marina norismario negri instituteVerified email at marionegri.it
