Extended exposure to stiff microenvironments leads to persistent chromatin remodeling in human mesenchymal stem cells AR Killaars, JC Grim, CJ Walker, EA Hushka, TE Brown, KS Anseth Advanced Science 6 (3), 1801483, 2019 | 170 | 2019 |
Nuclear mechanosensing drives chromatin remodelling in persistently activated fibroblasts CJ Walker, C Crocini, D Ramirez, AR Killaars, JC Grim, BA Aguado, ... Nature biomedical engineering 5 (12), 1485-1499, 2021 | 98* | 2021 |
Nuclear mechanosensing controls MSC osteogenic potential through HDAC epigenetic remodeling AR Killaars, CJ Walker, KS Anseth Proceedings of the National Academy of Sciences 117 (35), 21258-21266, 2020 | 79 | 2020 |
Transcatheter aortic valve replacements alter circulating serum factors to mediate myofibroblast deactivation BA Aguado, KB Schuetze, JC Grim, CJ Walker, AC Cox, TL Ceccato, ... Science translational medicine 11 (509), eaav3233, 2019 | 49 | 2019 |
Defining the cardiac fibroblast secretome in a fibrotic microenvironment TL Ceccato, RB Starbuck, JK Hall, CJ Walker, TE Brown, JP Killgore, ... Journal of the American Heart Association 9 (19), e017025, 2020 | 47 | 2020 |
Matters of the heart: cellular sex differences CJ Walker, ME Schroeder, BA Aguado, KS Anseth, LA Leinwand Journal of molecular and cellular cardiology 160, 42-55, 2021 | 42 | 2021 |
Nucleotide levels regulate germline proliferation through modulating GLP-1/Notch signaling in C. elegans C Chi, D Ronai, MT Than, CJ Walker, AK Sewell, M Han Genes & development 30 (3), 307-320, 2016 | 39 | 2016 |
Genes that escape X chromosome inactivation modulate sex differences in valve myofibroblasts BA Aguado, CJ Walker, JC Grim, ME Schroeder, D Batan, BJ Vogt, ... Circulation 145 (7), 513-530, 2022 | 36 | 2022 |
FGF-2 inhibits contractile properties of valvular interstitial cell myofibroblasts encapsulated in 3D MMP-degradable hydrogels A Gonzalez Rodriguez, ME Schroeder, CJ Walker, KS Anseth APL bioengineering 2 (4), 2018 | 35 | 2018 |
Three-dimensional encapsulation of adult mouse cardiomyocytes in hydrogels with tunable stiffness C Crocini, CJ Walker, KS Anseth, LA Leinwand Progress in Biophysics and Molecular Biology, 2019 | 34 | 2019 |
Inflammation via myeloid differentiation primary response gene 88 signaling mediates the fibrotic response to implantable synthetic poly (ethylene glycol) hydrogels LD Amer, LS Saleh, C Walker, S Thomas, WJ Janssen, S Alper, SJ Bryant Acta biomaterialia 100, 105-117, 2019 | 32 | 2019 |
Cardiac fibroblasts mediate a sexually dimorphic fibrotic response to β‐adrenergic stimulation AK Peter, CJ Walker, T Ceccato, CL Trexler, CD Ozeroff, KR Lugo, ... Journal of the American Heart Association 10 (11), e018876, 2021 | 26 | 2021 |
Collagen networks within 3D PEG hydrogels support valvular interstitial cell matrix mineralization ME Schroeder, AG Rodriguez, KF Speckl, CJ Walker, FS Midekssa, ... Acta biomaterialia 119, 197-210, 2021 | 22 | 2021 |
Mechanobiological interactions between dynamic compressive loading and viscoelasticity on chondrocytes in hydrazone covalent adaptable networks for cartilage tissue engineering BM Richardson, CJ Walker, MM Maples, MA Randolph, SJ Bryant, ... Advanced healthcare materials 10 (9), 2002030, 2021 | 21 | 2021 |
Viscoelasticity of hydrazone crosslinked poly (ethylene glycol) hydrogels directs chondrocyte morphology during mechanical deformation BM Richardson, CJ Walker, LJ Macdougall, JW Hoye, MA Randolph, ... Biomaterials science 8 (14), 3804-3811, 2020 | 21 | 2020 |
Tumor necrosis factor-α promotes and exacerbates calcification in heart valve myofibroblast populations AG Rodriguez, ME Schroeder, JC Grim, CJ Walker, KF Speckl, RM Weiss, ... FASEB journal: official publication of the Federation of American Societies …, 2021 | 19 | 2021 |
Extracellular matrix stiffness controls cardiac valve myofibroblast activation through epigenetic remodeling CJ Walker, D Batan, C Bishop, D Ramirez, BA Aguado, M Schroeder, ... Bioengineering & Translational Medicine, e10394, 2022 | 11 | 2022 |
Transcatheter aortic valve replacements alter circulating serum factors to mediate myofibroblast deactivation, Sci. Transl. Med. 11 (2019) eaav3233 BA Aguado, KB Schuetze, JC Grim, CJ Walker, AC Cox, TL Ceccato, ... | 5 | |
Osteopontin activity modulates sex‐specific calcification in engineered valve tissue mimics ME Schroeder, D Batan, A Gonzalez Rodriguez, KF Speckl, DK Peters, ... Bioengineering & translational medicine 8 (1), e10358, 2023 | 2 | 2023 |
Invitae's High-Throughput AMP-Based RUO VariantPlex NGS Workflow Offers Scalable and Customizable Targeted-Detection of Germline SNVs, Indels, and CNVs C Walker, L Hartje, K Hedges, C Picard JOURNAL OF MOLECULAR DIAGNOSTICS 24 (10), S26-S26, 2022 | | 2022 |