| Long-term microdystrophin gene therapy is effective in a canine model of Duchenne muscular dystrophy C Le Guiner, L Servais, M Montus, T Larcher, B Fraysse, S Moullec, ... Nature communications 8 (1), 16105, 2017 | 227 | 2017 |
| Adenovirus vector vaccination induces expansion of memory CD4 T cells with a mucosal homing phenotype that are readily susceptible to HIV-1 A Benlahrech, J Harris, A Meiser, T Papagatsias, J Hornig, P Hayes, ... Proceedings of the National Academy of Sciences 106 (47), 19940-19945, 2009 | 194 | 2009 |
| Codon and mRNA sequence optimization of microdystrophin transgenes improves expression and physiological outcome in dystrophic mdx mice following AAV2/8 gene transfer H Foster, PS Sharp, T Athanasopoulos, C Trollet, IR Graham, K Foster, ... Molecular therapy 16 (11), 1825-1832, 2008 | 140 | 2008 |
| Cell-derived apolipoprotein E (ApoE) particles inhibit vascular cell adhesion molecule-1 (VCAM-1) expression in human endothelial cells AK Stannard, DR Riddell, SM Sacre, AD Tagalakis, C Langer, ... Journal of Biological Chemistry 276 (49), 46011-46016, 2001 | 132 | 2001 |
| Nonintegrating gene therapy vectors T Athanasopoulos, MM Munye, RJ Yáñez-Muñoz Hematology/Oncology Clinics 31 (5), 753-770, 2017 | 116 | 2017 |
| Langerin negative dendritic cells promote potent CD8+ T-cell priming by skin delivery of live adenovirus vaccine microneedle arrays V Bachy, C Hervouet, PD Becker, L Chorro, LM Carlin, S Herath, ... Proceedings of the National Academy of Sciences 110 (8), 3041-3046, 2013 | 111 | 2013 |
| Triple trans-splicing adeno-associated virus vectors capable of transferring the coding sequence for full-length dystrophin protein into dystrophic mice T Koo, L Popplewell, T Athanasopoulos, G Dickson Human gene therapy 25 (2), 98-108, 2014 | 110 | 2014 |
| β‐catenin as a potential key target for tumor suppression Y Fu, S Zheng, N An, T Athanasopoulos, L Popplewell, A Liang, K Li, ... International journal of cancer 129 (7), 1541-1551, 2011 | 101 | 2011 |
| Abnormal splicing switch of DMD’s penultimate exon compromises muscle fibre maintenance in myotonic dystrophy F Rau, J Lainé, L Ramanoudjame, A Ferry, L Arandel, O Delalande, ... Nature communications 6 (1), 7205, 2015 | 96 | 2015 |
| Recombinant adeno-associated viral (rAAV) vectors as therapeutic tools for Duchenne muscular dystrophy (DMD) T Athanasopoulos, IR Graham, H Foster, G Dickson Gene therapy 11 (1), S109-S121, 2004 | 92 | 2004 |
| Long‐term functional adeno‐associated virus‐microdystrophin expression in the dystrophic CXMDj dog T Koo, T Okada, T Athanasopoulos, H Foster, S Takeda, G Dickson The journal of gene medicine 13 (9), 497-506, 2011 | 88 | 2011 |
| Gene therapy vectors based on adeno-associated virus: characteristics and applications to acquired and inherited diseases T Athanasopoulos, S Fabb, G Dickson International journal of molecular medicine 6 (4), 363-438, 2000 | 72 | 2000 |
| Delivery of AAV2/9-microdystrophin genes incorporating helix 1 of the coiled-coil motif in the C-terminal domain of dystrophin improves muscle pathology and restores the level … T Koo, A Malerba, T Athanasopoulos, C Trollet, L Boldrin, A Ferry, ... Human gene therapy 22 (11), 1379-1388, 2011 | 63 | 2011 |
| Gene therapy for muscular dystrophy: current progress and future prospects C Trollet, T Athanasopoulos, L Popplewell, A Malerba, G Dickson Expert Opinion on Biological Therapy 9 (7), 849-866, 2009 | 61 | 2009 |
| RNAi-mediated knockdown of dystrophin expression in adult mice does not lead to overt muscular dystrophy pathology MM Ghahramani Seno, IR Graham, T Athanasopoulos, C Trollet, ... Human molecular genetics 17 (17), 2622-2632, 2008 | 54 | 2008 |
| Inhibition of atherosclerosis in apolipoprotein-E-deficient mice following muscle transduction with adeno-associated virus vectors encoding human apolipoprotein-E JD Harris, S Schepelmann, T Athanasopoulos, IR Graham, AK Stannard, ... Gene therapy 9 (1), 21-29, 2002 | 51 | 2002 |
| Intramuscular injection of a plasmid vector expressing human apolipoprotein E limits progression of xanthoma and aortic atheroma in apoE-deficient mice T Athanasopoulos, JS Owen, D Hassall, MG Dunckley, J Drew, ... Human Molecular Genetics 9 (17), 2545-2551, 2000 | 50 | 2000 |
| Transcription factor rational design improves directed differentiation of human mesenchymal stem cells into skeletal myocytes MAFV Gonçalves, JM Janssen, QG Nguyen, T Athanasopoulos, ... Molecular Therapy 19 (7), 1331-1341, 2011 | 46 | 2011 |
| Genome-wide computational analysis reveals cardiomyocyte-specific transcriptional cis-regulatory motifs that enable efficient cardiac gene therapy MY Rincon, S Sarcar, D Danso-Abeam, M Keyaerts, J Matrai, ... Molecular Therapy 23 (1), 43-52, 2015 | 41 | 2015 |
| Transcriptomic analysis of dystrophin RNAi knockdown reveals a central role for dystrophin in muscle differentiation and contractile apparatus organization MM Ghahramani Seno, C Trollet, T Athanasopoulos, IR Graham, P Hu, ... BMC genomics 11, 1-12, 2010 | 40 | 2010 |
