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Abhay PS Rathore
Abhay PS Rathore
Duke University, Duke-NUS, NUS
Dirección de correo verificada de duke.edu
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Nuclear localization of dengue virus (DENV) 1–4 non-structural protein 5; protection against all 4 DENV serotypes by the inhibitor Ivermectin
MYF Tay, JE Fraser, WKK Chan, NJ Moreland, AP Rathore, C Wang, ...
Antiviral research 99 (3), 301-306, 2013
3632013
Adaptive immune responses to primary and secondary dengue virus infections
AL St. John, APS Rathore
Nature Reviews Immunology 19 (4), 218-230, 2019
2512019
Immune surveillance by mast cells during dengue infection promotes natural killer (NK) and NKT-cell recruitment and viral clearance
AL St. John, APS Rathore, H Yap, ML Ng, DD Metcalfe, SG Vasudevan, ...
Proceedings of the National Academy of Sciences 108 (22), 9190-9195, 2011
2512011
Efficacy and safety of celgosivir in patients with dengue fever (CELADEN): a phase 1b, randomised, double-blind, placebo-controlled, proof-of-concept trial
JG Low, C Sung, L Wijaya, Y Wei, APS Rathore, S Watanabe, BH Tan, ...
The Lancet infectious diseases 14 (8), 706-715, 2014
2332014
Contributions of mast cells and vasoactive products, leukotrienes and chymase, to dengue virus-induced vascular leakage
AL St John, APS Rathore, B Raghavan, ML Ng, SN Abraham
elife 2, e00481, 2013
1872013
Celgosivir treatment misfolds dengue virus NS1 protein, induces cellular pro-survival genes and protects against lethal challenge mouse model
APS Rathore, PN Paradkar, S Watanabe, KH Tan, C Sung, JE Connolly, ...
Antiviral research 92 (3), 453-460, 2011
1862011
Cross-reactive immunity among flaviviruses
APS Rathore, AL St. John
Frontiers in immunology 11, 334, 2020
1452020
Differential unfolded protein response during Chikungunya and Sindbis virus infection: CHIKV nsP4 suppresses eIF2α phosphorylation
APS Rathore, ML Ng, SG Vasudevan
Virology journal 10, 1-15, 2013
1212013
Maternal immunity and antibodies to dengue virus promote infection and Zika virus–induced microcephaly in fetuses
APS Rathore, WAA Saron, T Lim, N Jahan, AL St. John
Science Advances 5 (2), eaav3208, 2019
1122019
Chikungunya virus nsP3 & nsP4 interacts with HSP-90 to promote virus replication: HSP-90 inhibitors reduce CHIKV infection and inflammation in vivo
APS Rathore, T Haystead, PK Das, A Merits, ML Ng, SG Vasudevan
Antiviral research 103, 7-16, 2014
1072014
Dose-and schedule-dependent protective efficacy of celgosivir in a lethal mouse model for dengue virus infection informs dosing regimen for a proof of concept clinical trial
S Watanabe, APS Rathore, C Sung, F Lu, YM Khoo, J Connolly, J Low, ...
Antiviral research 96 (1), 32-35, 2012
1052012
Fetal mast cells mediate postnatal allergic responses dependent on maternal IgE
R Msallam, J Balla, APS Rathore, H Kared, B Malleret, WAA Saron, Z Liu, ...
Science 370 (6519), 941-950, 2020
912020
Flavivirus serocomplex cross-reactive immunity is protective by activating heterologous memory CD4 T cells
WAA Saron, APS Rathore, L Ting, EE Ooi, J Low, SN Abraham, ...
Science advances 4 (7), eaar4297, 2018
792018
Dengue virus–elicited tryptase induces endothelial permeability and shock
APS Rathore, CK Mantri, SAB Aman, A Syenina, J Ooi, CJ Jagaraj, ...
The Journal of clinical investigation 129 (10), 4180-4193, 2019
762019
Japanese encephalitis virus neuropenetrance is driven by mast cell chymase
JT Hsieh, APS Rathore, G Soundarajan, AL St. John
Nature communications 10 (1), 706, 2019
722019
The magnitude of dengue virus NS1 protein secretion is strain dependent and does not correlate with severe pathologies in the mouse infection model
S Watanabe, KH Tan, APS Rathore, K Rozen-Gagnon, W Shuai, C Ruedl, ...
Journal of virology 86 (10), 5508-5514, 2012
722012
Early insights into immune responses during COVID-19
AL St John, APS Rathore
The Journal of Immunology 205 (3), 555-564, 2020
672020
Chymase level is a predictive biomarker of dengue hemorrhagic fever in pediatric and adult patients
H Tissera, APS Rathore, WY Leong, BL Pike, TE Warkentien, FS Farouk, ...
The Journal of infectious diseases 216 (9), 1112-1121, 2017
592017
Extended evaluation of virological, immunological and pharmacokinetic endpoints of CELADEN: a randomized, placebo-controlled trial of celgosivir in dengue fever patients
C Sung, Y Wei, S Watanabe, HS Lee, YM Khoo, L Fan, APS Rathore, ...
PLoS neglected tropical diseases 10 (8), e0004851, 2016
592016
New perspectives on the origins and heterogeneity of mast cells
AL St. John, APS Rathore, F Ginhoux
Nature Reviews Immunology 23 (1), 55-68, 2023
512023
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Artículos 1–20