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| Designed divergent evolution of enzyme function Y Yoshikuni, TE Ferrin, JD Keasling Nature 440 (7087), 1078-1082, 2006 | 530 | 2006 |
| Efficient ethanol production from brown macroalgae sugars by a synthetic yeast platform M Enquist-Newman, AME Faust, DD Bravo, CNS Santos, RM Raisner, ... Nature 505 (7482), 239-243, 2014 | 366 | 2014 |
| Computational protein design enables a novel one-carbon assimilation pathway JB Siegel, AL Smith, S Poust, AJ Wargacki, A Bar-Even, C Louw, ... Proceedings of the National Academy of Sciences 112 (12), 3704-3709, 2015 | 349 | 2015 |
| 1,003 reference genomes of bacterial and archaeal isolates expand coverage of the tree of life S Mukherjee, R Seshadri, NJ Varghese, EA Eloe-Fadrosh, ... Nature biotechnology 35 (7), 676-683, 2017 | 243 | 2017 |
| A Novel Semi-biosynthetic Route for Artemisinin Production Using Engineered Substrate-Promiscuous P450BM3 JA Dietrich, Y Yoshikuni, KJ Fisher, FX Woolard, D Ockey, DJ McPhee, ... ACS chemical biology 4 (4), 261-267, 2009 | 229 | 2009 |
| Microbiome engineering: synthetic biology of plant-associated microbiomes in sustainable agriculture J Ke, B Wang, Y Yoshikuni Trends in Biotechnology 39 (3), 244-261, 2021 | 217 | 2021 |
| Mono and diterpene production in Escherichia coli KK Reiling, Y Yoshikuni, VJJ Martin, J Newman, J Bohlmann, JD Keasling Biotechnology and bioengineering 87 (2), 200-212, 2004 | 195 | 2004 |
| Genome-wide identification of bacterial plant colonization genes BJ Cole, ME Feltcher, RJ Waters, KM Wetmore, TS Mucyn, EM Ryan, ... PLoS Biology 15 (9), e2002860, 2017 | 186 | 2017 |
| Directed evolution of AraC for improved compatibility of arabinose-and lactose-inducible promoters SK Lee, HH Chou, BF Pfleger, JD Newman, Y Yoshikuni, JD Keasling Applied and environmental microbiology 73 (18), 5711-5715, 2007 | 150 | 2007 |
| The in vivo synthesis of plant sesquiterpenes by Escherichia coli VJJ Martin, Y Yoshikuni, JD Keasling Biotechnology and bioengineering 75 (5), 497-503, 2001 | 144 | 2001 |
| Engineering cotton (+)-δ-cadinene synthase to an altered function: germacrene D-4-ol synthase Y Yoshikuni, VJJ Martin, TE Ferrin, JD Keasling Chemistry & biology 13 (1), 91-98, 2006 | 110 | 2006 |
| CRAGE enables rapid activation of biosynthetic gene clusters in undomesticated bacteria G Wang, Z Zhao, J Ke, Y Engel, YM Shi, D Robinson, K Bingol, Z Zhang, ... Nature microbiology 4 (12), 2498-2510, 2019 | 106 | 2019 |
| Biosynthesis of isopentenyl pyrophosphate J Keasling, V Martin, D Pitera, SW Kim, ST Withers III, Y Yoshikuni, ... US Patent 7,172,886, 2007 | 105 | 2007 |
| Validating genome-wide CRISPR-Cas9 function improves screening in the oleaginous yeast Yarrowia lipolytica C Schwartz, JF Cheng, R Evans, CA Schwartz, JM Wagner, S Anglin, ... Metabolic engineering 55, 102-110, 2019 | 90 | 2019 |
| Implementation of stable and complex biological systems through recombinase-assisted genome engineering CNS Santos, DD Regitsky, Y Yoshikuni Nature communications 4 (1), 2503, 2013 | 85 | 2013 |
| Function-driven single-cell genomics uncovers cellulose-degrading bacteria from the rare biosphere DFR Doud, RM Bowers, F Schulz, M De Raad, K Deng, A Tarver, ... The ISME journal 14 (3), 659-675, 2020 | 74 | 2020 |
| Redesigning enzymes based on adaptive evolution for optimal function in synthetic metabolic pathways Y Yoshikuni, JA Dietrich, FF Nowroozi, PC Babbitt, JD Keasling Chemistry & biology 15 (6), 607-618, 2008 | 71 | 2008 |
| Ecosystem fabrication (EcoFAB) protocols for the construction of laboratory ecosystems designed to study plant-microbe interactions J Gao, J Sasse, KM Lewald, K Zhalnina, LT Cornmesser, TA Duncombe, ... JoVE (Journal of Visualized Experiments), e57170, 2018 | 65 | 2018 |
| Rare earth element alcohol dehydrogenases widely occur among globally distributed, numerically abundant and environmentally important microbes J Huang, Z Yu, J Groom, JF Cheng, A Tarver, Y Yoshikuni, ... The ISME Journal 13 (8), 2005-2017, 2019 | 62 | 2019 |
