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Paola Oliva
Paola Oliva
Dirección de correo verificada de nih.gov - Página principal
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Design, Synthesis, and Biological Evaluation of 6-Substituted Thieno[3,2-d]pyrimidine Analogues as Dual Epidermal Growth Factor Receptor Kinase and …
R Romagnoli, F Prencipe, P Oliva, S Baraldi, PG Baraldi, ...
Journal of Medicinal Chemistry 62 (3), 1274-1290, 2019
392019
Design and Synthesis of Potent in Vitro and in Vivo Anticancer Agents Based on 1-(3′,4′,5′-Trimethoxyphenyl)-2-Aryl-1H-Imidazole
R Romagnoli, PG Baraldi, F Prencipe, P Oliva, S Baraldi, MA Tabrizi, ...
Scientific reports 6 (1), 26602, 2016
372016
Design, synthesis and biological evaluation of 3-substituted-2-oxindole hybrid derivatives as novel anticancer agents
R Romagnoli, PG Baraldi, F Prencipe, P Oliva, S Baraldi, MK Salvador, ...
European Journal of Medicinal Chemistry 134, 258-270, 2017
302017
Design, synthesis, in vitro and in vivo biological evaluation of 2-amino-3-aroylbenzo [b] furan derivatives as highly potent tubulin polymerization inhibitors
P Oliva, R Romagnoli, S Manfredini, A Brancale, S Ferla, E Hamel, ...
European Journal of Medicinal Chemistry 200, 112448, 2020
262020
Design, synthesis and biological evaluation of novel vicinal diaryl-substituted 1H-Pyrazole analogues of combretastatin A-4 as highly potent tubulin polymerization inhibitors
R Romagnoli, P Oliva, MK Salvador, ME Camacho, C Padroni, A Brancale, ...
European Journal of Medicinal Chemistry 181, 111577, 2019
242019
Synthesis and biological evaluation of 2-methyl-4, 5-disubstituted oxazoles as a novel class of highly potent antitubulin agents
R Romagnoli, PG Baraldi, F Prencipe, P Oliva, S Baraldi, MK Salvador, ...
Scientific reports 7 (1), 46356, 2017
222017
Cinnamic acid derivatives linked to arylpiperazines as novel potent inhibitors of tyrosinase activity and melanin synthesis
R Romagnoli, P Oliva, F Prencipe, S Manfredini, MP Germanò, L De Luca, ...
European Journal of Medicinal Chemistry 231, 114147, 2022
212022
Design, synthesis and biological evaluation of 2-alkoxycarbonyl-3-anilinoindoles as a new class of potent inhibitors of tubulin polymerization
R Romagnoli, F Prencipe, P Oliva, MK Salvador, A Brancale, S Ferla, ...
Bioorganic Chemistry 97, 103665, 2020
192020
3-Aryl/Heteroaryl-5-amino-1-(3′, 4′, 5′-trimethoxybenzoyl)-1, 2, 4-triazoles as antimicrotubule agents. Design, synthesis, antiproliferative activity and inhibition of …
R Romagnoli, F Prencipe, P Oliva, S Baraldi, PG Baraldi, A Brancale, ...
Bioorganic chemistry 80, 361-374, 2018
192018
Arylamidonaphtalene sulfonate compounds as a novel class of heparanase inhibitors
R Rondanin, S Fochi, R Baruchello, T Bernardi, P Oliva, F Semeraro, ...
Bioorganic & Medicinal Chemistry Letters 27 (18), 4421-4425, 2017
192017
New TRAP1 and Hsp90 chaperone inhibitors with cationic components: Preliminary studies on mitochondrial targeting
R Rondanin, G Lettini, P Oliva, R Baruchello, C Costantini, C Trapella, ...
Bioorganic & Medicinal Chemistry Letters 28 (13), 2289-2293, 2018
182018
2-Alkoxycarbonyl-3-arylamino-5-substituted thiophenes as a novel class of antimicrotubule agents: Design, synthesis, cell growth and tubulin polymerization inhibition
R Romagnoli, MK Salvador, SS Ortega, PG Baraldi, P Oliva, S Baraldi, ...
European journal of medicinal chemistry 143, 683-698, 2018
162018
A facile synthesis of diaryl pyrroles led to the discovery of potent colchicine site antimitotic agents
R Romagnoli, P Oliva, MK Salvador, S Manfredini, C Padroni, A Brancale, ...
European Journal of Medicinal Chemistry 214, 113229, 2021
142021
Synthesis and biological evaluation of alpha-bromoacryloylamido indolyl pyridinyl propenones as potent apoptotic inducers in human leukaemia cells
R Romagnoli, F Prencipe, LC Lopez-Cara, P Oliva, S Baraldi, PG Baraldi, ...
Journal of Enzyme Inhibition and Medicinal Chemistry 33 (1), 727-742, 2018
142018
Apoptosis pathways triggered by a potent antiproliferative hybrid chalcone on human melanoma cells
I Rodríguez, E Saavedra, H Del Rosario, J Perdomo, J Quintana, ...
International Journal of Molecular Sciences 22 (24), 13462, 2021
122021
Synthesis and biological evaluation of new antitubulin agents containing 2-(3′, 4′, 5′-trimethoxyanilino)-3, 6-disubstituted-4, 5, 6, 7-tetrahydrothieno [2, 3-c] pyridine …
R Romagnoli, F Prencipe, P Oliva, B Cacciari, J Balzarini, S Liekens, ...
Molecules 25 (7), 1690, 2020
122020
The novel antitubulin agent TR-764 strongly reduces tumor vasculature and inhibits HIF-1α activation
E Porcù, L Persano, R Ronca, S Mitola, R Bortolozzi, R Romagnoli, ...
Scientific Reports 6 (1), 27886, 2016
112016
Synergistic Effects of A Combined Treatment of Glioblastoma U251 Cells with An Anti-miR-10b-5p Molecule and An AntiCancer Agent Based on 1-(3′, 4′, 5′-Trimethoxyphenyl)-2 …
M Zurlo, R Romagnoli, P Oliva, J Gasparello, A Finotti, R Gambari
International Journal of Molecular Sciences 23 (11), 5991, 2022
92022
Structure-activity relationships of pyrimidine nucleotides containing a 5′-α, β-methylene diphosphonate at the P2Y6 receptor
P Oliva, M Scortichini, C Dobelmann, S Jain, V Gopinatth, KS Toti, ...
Bioorganic & medicinal chemistry letters 45, 128137, 2021
82021
A2A Adenosine Receptor: Structures, Modeling, and Medicinal Chemistry
S Baraldi, PG Baraldi, P Oliva, KS Toti, A Ciancetta, KA Jacobson
The Adenosine Receptors, 91-136, 2018
82018
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