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Johannes Brägelmann, MD, MSc
Johannes Brägelmann, MD, MSc
Mildred Scheel School of Oncology, Dpt. of Translational Genomics, University of Cologne
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Integrative and comparative genomic analysis of HPV-positive and HPV-negative head and neck squamous cell carcinomas
TY Seiwert, Z Zuo, MK Keck, A Khattri, CS Pedamallu, T Stricker, C Brown, ...
Clinical cancer research 21 (3), 632-641, 2015
6602015
MYC drives progression of small cell lung cancer to a variant neuroendocrine subtype with vulnerability to aurora kinase inhibition
G Mollaoglu, MR Guthrie, S Böhm, J Brägelmann, I Can, PM Ballieu, ...
Cancer cell 31 (2), 270-285, 2017
4592017
Integrative analysis of head and neck cancer identifies two biologically distinct HPV and three non-HPV subtypes
MK Keck, Z Zuo, A Khattri, TP Stricker, CD Brown, M Imanguli, D Rieke, ...
Clinical cancer research 21 (4), 870-881, 2015
3772015
K-ras mutation subtypes in NSCLC and associated co-occuring mutations in other oncogenic pathways
M Scheffler, MA Ihle, R Hein, S Merkelbach-Bruse, AH Scheel, ...
Journal of Thoracic Oncology 14 (4), 606-616, 2019
2052019
Web-TCGA: an online platform for integrated analysis of molecular cancer data sets
M Deng, J Brägelmann, JL Schultze, S Perner
BMC bioinformatics 17, 1-7, 2016
1782016
FirebrowseR: an R client to the Broad Institute’s Firehose Pipeline
M Deng, J Brägelmann, I Kryukov, N Saraiva-Agostinho, S Perner
Database 2017, baw160, 2017
1712017
Overcoming EGFRG724S-mediated osimertinib resistance through unique binding characteristics of second-generation EGFR inhibitors
J Fassunke, F Müller, M Keul, S Michels, MA Dammert, A Schmitt, ...
Nature communications 9 (1), 4655, 2018
1292018
PD-L1: a novel prognostic biomarker in head and neck squamous cell carcinoma
T Müller, M Braun, D Dietrich, S Aktekin, S Höft, G Kristiansen, F Göke, ...
Oncotarget 8 (32), 52889, 2017
1142017
RON (MST1R) is a novel prognostic marker and therapeutic target for gastroesophageal adenocarcinoma
DVT Catenacci, G Cervantes, S Yala, EA Nelson, E El-Hashani, R Kanteti, ...
Cancer biology & therapy 12 (1), 9-46, 2011
1052011
Pan-cancer analysis of the mediator complex transcriptome identifies CDK19 and CDK8 as therapeutic targets in advanced prostate cancer
J Brägelmann, N Klümper, A Offermann, A Von Maessenhausen, D Böhm, ...
Clinical Cancer Research 23 (7), 1829-1840, 2017
932017
Structural alterations of MET trigger response to MET kinase inhibition in lung adenocarcinoma patients
D Plenker, M Bertrand, AJ de Langen, R Riedel, C Lorenz, AH Scheel, ...
Clinical Cancer Research 24 (6), 1337-1343, 2018
832018
Family matters: How MYC family oncogenes impact small cell lung cancer
J Brägelmann, S Boehm, MR Guthrie, G Mollaoglu, TG Oliver, ML Sos
Cell Cycle 16 (16), 1489-1498, 2017
782017
Performance of the CHARGE-AF risk model for incident atrial fibrillation in the EPIC Norfolk cohort
R Pfister, J Brägelmann, G Michels, NJ Wareham, R Luben, KT Khaw
European journal of preventive cardiology 22 (7), 932-939, 2015
732015
MYC paralog-dependent apoptotic priming orchestrates a spectrum of vulnerabilities in small cell lung cancer
MA Dammert, J Brägelmann, RR Olsen, S Böhm, N Monhasery, ...
Nature communications 10 (1), 3485, 2019
642019
Drugging the catalytically inactive state of RET kinase in RET-rearranged tumors
D Plenker, M Riedel, J Brägelmann, MA Dammert, R Chauhan, ...
Science translational medicine 9 (394), eaah6144, 2017
632017
Recurrent HNSCC harbor an immunosuppressive tumor immune microenvironment suggesting successful tumor immune evasion
C Watermann, H Pasternack, C Idel, J Ribbat-Idel, J Braegelmann, ...
Clinical cancer research 27 (2), 632-644, 2021
612021
Oral cavity tumors in younger patients show a poor prognosis and do not contain viral RNA
J Brägelmann, I Dagogo-Jack, M El Dinali, T Stricker, CD Brown, Z Zuo, ...
Oral oncology 49 (6), 525-533, 2013
572013
Mechanisms of Primary Drug Resistance in FGFR1-Amplified Lung Cancer
F Malchers, M Ercanoglu, D Schütte, R Castiglione, V Tischler, S Michels, ...
Clinical Cancer Research 23 (18), 5527-5536, 2017
562017
Systematic kinase inhibitor profiling identifies CDK9 as a synthetic lethal target in NUT midline carcinoma
J Brägelmann, MA Dammert, F Dietlein, JM Heuckmann, A Choidas, ...
Cell reports 20 (12), 2833-2845, 2017
472017
Elevated FSP1 protects KRAS-mutated cells from ferroptosis during tumor initiation
F Müller, JKM Lim, CM Bebber, E Seidel, S Tishina, A Dahlhaus, J Stroh, ...
Cell Death & Differentiation 30 (2), 442-456, 2023
412023
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