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Wang-Qing Liu
Wang-Qing Liu
Faculté de Pharmacie Paris
Dirección de correo verificada de u-paris.fr
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STAT3-stathmin interactions control microtubule dynamics in migrating T-cells
NK Verma, J Dourlat, AM Davies, A Long, WQ Liu, C Garbay, D Kelleher, ...
Journal of biological chemistry 284 (18), 12349-12362, 2009
1232009
The synaptic acetylcholinesterase tetramer assembles around a polyproline II helix
H Dvir, M Harel, S Bon, WQ Liu, M Vidal, C Garbay, JL Sussman, ...
The EMBO journal 23 (22), 4394-4405, 2004
1222004
A Sos‐derived peptidimer blocks the Ras signaling pathway by binding both Grb2 SH3 domains and displays antiproliferative activity
D CUSSAC, M VIDAL, C LEPRINCE, WQ LIU, F CORNILLE, ...
The FASEB journal 13 (1), 31-39, 1999
1181999
Crystal structures of the SH2 domain of Grb2: highlight on the binding of a new high-affinity inhibitor
P Nioche, WQ Liu, I Broutin, F Charbonnier, MT Latreille, M Vidal, ...
Journal of molecular biology 315 (5), 1167-1177, 2002
1132002
Neuropilin-1 regulates a new VEGF-induced gene, Phactr-1, which controls tubulogenesis and modulates lamellipodial dynamics in human endothelial cells
B Allain, R Jarray, L Borriello, B Leforban, S Dufour, W Liu, ...
Cellular signalling 24 (1), 214-223, 2012
842012
Novel 1, 4-benzodiazepine derivatives with antiproliferative properties on tumor cell lines
J Dourlat, WQ Liu, N Gresh, C Garbay
Bioorganic & medicinal chemistry letters 17 (9), 2527-2530, 2007
682007
M-CSF stimulated differentiation requires persistent MEK activity and MAPK phosphorylation independent of Grb2–Sos association and phosphatidylinositol 3-kinase activity
SG Gosse, C Bourgin, WQ Liu, C Garbay, G Mouchiroud
Cellular signalling 17 (11), 1352-1362, 2005
672005
Inhibitors of Ras signal transduction as antitumor agents
C Garbay, WQ Liu, M Vidal, BP Roques
Biochemical pharmacology 60 (8), 1165-1169, 2000
612000
Structure-based discovery of a small non-peptidic Neuropilins antagonist exerting in vitro and in vivo anti-tumor activity on breast cancer model
L Borriello, M Montès, Y Lepelletier, B Leforban, WQ Liu, L Demange, ...
Cancer letters 349 (2), 120-127, 2014
522014
Grb2‐SH3 ligand inhibits the growth of HER2+ cancer cells and has antitumor effects in human cancer xenografts alone and in combination with docetaxel
B Gril, M Vidal, F Assayag, MF Poupon, WQ Liu, C Garbay
International journal of cancer 121 (2), 407-415, 2007
512007
Small peptides containing phosphotyrosine and adjacent αMe-phosphotyrosine or its mimetics as highly potent inhibitors of Grb2 SH2 domain
WQ Liu, M Vidal, N Gresh, BP Roques, C Garbay
Journal of medicinal chemistry 42 (18), 3737-3741, 1999
511999
Structure− activity relationships of small phosphopeptides, inhibitors of Grb2 SH2 domain, and their prodrugs
WQ Liu, M Vidal, C Olszowy, E Million, C Lenoir, H Dhôtel, C Garbay
Journal of medicinal chemistry 47 (5), 1223-1233, 2004
492004
Disruption of phactr-1 pathway triggers pro-inflammatory and pro-atherogenic factors: New insights in atherosclerosis development
R Jarray, S Pavoni, L Borriello, B Allain, N Lopez, S Bianco, WQ Liu, ...
Biochimie 118, 151-161, 2015
422015
NRPa-308, a new neuropilin-1 antagonist, exerts in vitro anti-angiogenic and anti-proliferative effects and in vivo anti-cancer effects in a mouse xenograft model
WQ Liu, Y Lepelletier, M Montès, L Borriello, R Jarray, R Grépin, ...
Cancer Letters 414, 88-98, 2018
362018
Synthesis and structure–activity relationship of non-peptidic antagonists of neuropilin-1 receptor
WQ Liu, V Megale, L Borriello, B Leforban, M Montès, E Goldwaser, ...
Bioorganic & Medicinal Chemistry Letters 24 (17), 4254-4259, 2014
362014
Design of peptoid analogue dimers and measure of their affinity for Grb2 SH3 domains
M Vidal, WQ Liu, C Lenoir, J Salzmann, N Gresh, C Garbay
Biochemistry 43 (23), 7336-7344, 2004
342004
New syntheses of tetrazolylmethylphenylalanine and O-malonyltyrosine as pTyr mimetics for the design of STAT3 dimerization inhibitors
J Dourlat, B Valentin, WQ Liu, C Garbay
Bioorganic & medicinal chemistry letters 17 (14), 3943-3946, 2007
332007
Assembly of acetylcholinesterase tetramers by peptidic motifs from the proline-rich membrane anchor, PRiMA: competition between degradation and secretion pathways of …
H Noureddine, C Schmitt, W Liu, C Garbay, J Massoulié, S Bon
Journal of biological chemistry 282 (6), 3487-3497, 2007
312007
LC–MS/MS-based quantification of efflux transporter proteins at the BBB
D Gomez-Zepeda, M Taghi, M Smirnova, P Sergent, WQ Liu, C Chhuon, ...
Journal of Pharmaceutical and Biomedical Analysis 164, 496-508, 2019
292019
Differential effect of the inhibition of Grb2–SH3 interactions in platelet activation induced by thrombin and by Fc receptor engagement
A Saci, WQ Liu, M Vidal, C Garbay, F Rendu, C Bachelot-Loza
Biochemical Journal 363 (3), 717-725, 2002
292002
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